Alzheimer’s disease: newer modalities in treatment

Authors

  • Ammaar Riyaz Syed RAKCOMS, RAKMHSU, UAE
  • Ayman Ahmad Alothman Agha RAKCOMS, RAKMHSU, UAE
  • Ibrahim Mirgani Saleem Mohamed RAKCOMS, RAKMHSU, UAE
  • Suresh Kumar Srinivasamurthy Department of Pharmacology, RAKCOMS, RAKMHSU, UAE

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20243045

Keywords:

AD, Monoclonal antibody, Degenerative brain disease, Clinical development for AD

Abstract

Alzheimer’s disease (AD) remains insurmountable despite a long history of research and clinical development. It is projected to rise in the coming decades of public health due to the aging population worldwide. Understanding the basic tenets of the disease and targeting key steps remains a time-tested approach even for AD. Apart from the currently available treatment options namely NMDA blockers, and acetylcholinesterase inhibitors, recently monoclonal antibodies that target Aβ amyloid protein are approved. This review highlights the key features of currently approved drugs along with promising drugs in clinical development.

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Published

2024-10-23

How to Cite

Syed, A. R., Agha, A. A. A., Mohamed, I. M. S., & Srinivasamurthy, S. K. (2024). Alzheimer’s disease: newer modalities in treatment. International Journal of Basic & Clinical Pharmacology, 13(6), 915–921. https://doi.org/10.18203/2319-2003.ijbcp20243045