Therapeutic potential of seaweeds


  • Rajeev Goel Department of Biophysics, Dr. Rajenrda Prasad Government Medical College, Kangra at Tanda, Himachal Pradesh, India
  • Tushar Saini Department of Forensic Medicine, Dr. Rajenrda Prasad Government Medical College, Kangra at Tanda, Himachal Pradesh, India
  • Binny Mahendru Department of Pharmacology, Dr Radhakrishnan Government Medical College, Hamirpur, Himachal Pradesh, India



Seaweeds or vegetables, Marine natural products, Marine pharmacology, Marine therapeutics


Seaweeds in general are known to contribute to the maintenance of health through their nutritional and medicinal properties and are served in soups and salads, cooked with grains, legumes or miso-soup broth, vegetable pies, stews and even consumed dried. The medicinal properties of seaweeds or vegetables have long been known in many cultures of people particularly those living in the coastal regions who are consuming these from centuries. Traditional Chinese dietotherapy (TCD) makes good use of natural marine nutrients and food to preserve health. Koreans wrap their bodies in seaweeds to get rid of deadly body toxins and Japanese who eat large quantities of seaweeds have very low incidence of cancers. The compounds with diverse biological activities such as antioxidant, antiviral, antifungal, antineoplastic, antimicrobial etc. have been isolated from the flora in the sea. A score of these bio-medicinal compounds are in different stages of clinical trials & analysis and are the focus of this article. 

Author Biography

Rajeev Goel, Department of Biophysics, Dr. Rajenrda Prasad Government Medical College, Kangra at Tanda, Himachal Pradesh, India

Professor & Head

Deptt. of Biophysics


Ellouali M, Boisson-Vidal C, Durand P. Antitumor activity of low mol. W. fucans extracted from brown seaweed Ascophyllum nodosum. Anticancer Res. 1993;13(6A):2011-20.

Le Tutour B, Benslimane F, Gouleau MP. Antioxidant and Pro-oxidant activities of the brown algae, Laminaria digitala, Himanthalia elongata, Fucus vesiculosus, Fucus serratus and Ascophyllum nodsum. J Applied Phycol. 1998;10(2);121-9.

Lamela M, Anca J, Villar R. Hyproglycemic activity of several seaweed extrals. J Ethnopharmacol. 1989;27(1-2):35-43.

Clark CD, Bassett B, Burge MR. Effect of kelp Supplementation on thyroid function in erythroid subjects, Endocr Pract. 2003;9(5)363-9.

Durig J, Bruhn T, Zurborn KH. Anticogulant fucoidan fractions from Fucus vesiculosus induce plate activation in vitro. Thromb Res. 1997;85(6);479-91.

Teas J, Braverman LE, Kurzer MS. Seaweeds and Soy: Companion foods in Asian cuisine and their effects on thyroid function in American women. J Med Food. 2007;10(1):90-100.

Seaweeds, kelp, bladdderwraclr (Fucus vesiculosus). Available at: http;// druginfo/natural/patient_bladderwrack.html. Accessed on 10 Jan, 2020.

Aisa Y, Miyakawa Y, Nakazato T, Shibata H, Saitok K, Ikeda Y et al. Fucoidan induced apoptosis of human HS-sultan cells accompanied by caspase 3 activation and down regulation of ERK pathways. J Hematol. 2005;78(1):7-14.

Deux JF, Meddahi-Pelle A, Le Blanche AF, Colliec LJFS, Jouault, Low M. Fucoidan prevents neo intimal hyperplasia in Rabbit iliac artery in Stent restenosis model. Atherosclerosis, Thrombosis vascular biol. 2002;22:1604-9.

Thiomas D. Seaweeds, The Natural History Museum, London. 2002.

Hwang HJ, Jin Kwon M, Kim IH, Nam TJ. Chemoprotective effects of a protein from the red algae Porphyra yezoensis on acetaminophen induced liver injury in rats. Phytotherapy Res. 2008;22(9):1149-53.

Yuan YV, Carrington MF, Walsh NA. Extracts from Dulse (Palmaria palmta) are effective antioxidants and inhibitors of cell proliferation in vitro. Food Chem toxicol. 2005;43:1073-81.

Bensemir A, Blume M, Schroder S, Lindequist Li. Screening of cultivated seaweeds for antibacterial activity against fish pathogenic bacteria. Aquaculture. 2006;252:79-84.

Chew YL, Lim YY, Omar M, Khoo KS. Antioxidant activity of Three selected brown seaweeds of India. Food Chem. 2008;107:707-13.

Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K. Flucoxanthin from edible seaweeds, Undaria pinnatifida, shows anti-obesity effect Through UCP1 expression in white adipose tissues. Biochem Biophys Res Commun. 2005;332(2);392-7.

Eitsuka T, Nakagawak, Igarashi M, Miyazawai T. Telomerase inhibition by sulfo-quinovosyl diacylglycerol from edible purpule Laver (Pophyra yezoensis). Cancer felt. 2004. 2021;2(1):15-20.

Burges D. Watson Public health and Carrageenan regulation: A review and analysis. J App Phycol. 2007;20:55-63.

Cox S, Abu-Ghannam N, Gupta S. An assessment of the antioxidant and antimicrobial activity of sex species of edible Irish seaweeds. Int. Food Res J. 2001;17:205-20.

Ivanova V, Rouseva R, Kolarava M, Serkedjieva J, Rachev R, Menolova N. Isolation of a polysaccharide with antiviral effect from Ulva Lactuca. Preparative Biochem Biotechnol. 1994;24;83-97.

Cooper R, lesDragar C, Elliot K, Fitton JH, Godwin J, Thompson K. A preparation of Tasmanian Undaria pinnatifida is associated with healing and inhibition of reactivation of Herpes. BMC complementary Alternative Med. 2002;2:11.

Shen BE, Yoshida Y, Kuroda E, Yameshita U. Immuno modulatory activity of seaweed extract of human lymphocytes in vitro. Int J Immunopharmacol. 1999;21(1):59-70.

Drum R. In: Sea vegetables for foods and medicine. Available at: article.Pdf. Accessed on 10 Jan. 2020.

Drum R. Medicinial uses of seaweeds, Island Herbs Accessed on 10 Jan. 2020.

Skibola CF. The effect of Fucus vesiculosus an edible brown seaweed, upon menstrual cycle length and hormonal status in pre-menstrual women: A Case report. BMC Complement Altern Med. 2004;4:10.

SatoMoba T, Yamaguchi T, Nakano T, Kahar T, Funayama K, Kabayashi A. Antihypertensive effects of hydro lysates of Wakame and their angiotensin converting anytime inhibitory activity. Ann Nutr Metab. 2002;46:259-67.

Abodussalam S. Drugs from Seaweeds. Med Hypothesis. 1991;32:33-5.

Bocanegra A, Bastida S, Benedi J, Rodenas S, Sanchez Muniz FJ. Characteristics and nutritional and Cardiovascular health properties of seaweeds. J Med Food. 2009;12:236-58.

Jimenez-Escrig A, Goni Combrodon I. Nutritional evaluation and physiological effects of seaweeds. Arch Latinoam Nutr. 1999;49(2):114-20.

Armisen R. Worldwide use and importance of Gracilaria. J Appl Phycol. 1995;7:231-43.

Albertus S. Medicinal and pharmaceutical uses of seaweed natural products: A Review. J Appl Phycol. 2004;16:245-62.

Khalid S, Abbas M, Saeed F, Bader-Ul-Ain H, Rasul Suleria HA. Therapeutic Potential of Seaweed Bioactive Compounds, Seaweed Biomaterials, 2018, Sabyasachi Maiti, IntechOpen. Available from: Accessed on 10 Jan. 2020.

Salehi B, Sharifi-Rad J, Ana ML, Diana CGA, Pinto M, Trincone A et al. Current trends on seaweeds: Looking at chemical composition, phytopharmacology, and cosmetic applications. Molecules. 2019;24(22):4182

Irkin LC, Yayintas Ö. Pharmacological Properties and Therapeutic Benefits of Seaweeds (A Review). Int J Trend Sci Res Dev. 2018;2:1126-31.

Pal A, Kamthania MC, Kumar A. Bioactive Compounds and Properties of Seaweeds: A Review. Open Access Libr J. 2014;1:e752.

Madhusudan C, Manoj S, Rhaul K, Rishi C. Seaweeds: A Diet with nutritional, medicinal and industrial value. Res J Med Plant. 2011;5:153-7.




How to Cite

Goel, R., Saini, T., & Mahendru, B. (2021). Therapeutic potential of seaweeds. International Journal of Basic & Clinical Pharmacology, 10(5), 591–595.



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