Study of knowledge, attitude, practice of rational use of medicines among interns at Mc Gann teaching district hospital, Shivamogga- a descriptive cross-sectional study

Vedavathi Hanumaiah, Shreenivas Revankar, Abhishek C. P.


Background: Rational use of medicines requires that the patients receive medication appropriate to their clinical needs, in doses that meet their own individual requirements for an adequate period of lime, and at the lowest cost to them and to their community. Objective of the study were like descriptive cross- sectional study was conducted to determine and identify the level of knowledge, attitude and practice regarding rational use of medicines among the interns.

Methods: A validated structured questionnaire containing 19 questions regarding rational use of medicines in knowledge, attitude and practice (KAP) format was distributed in hand among 109 interns affiliated to this institution. Descriptive statistics were used to illustrate the results in the form of number and percentage.

Results: Out of 109 interns, 102 completed the questionnaire and were included in the final analysis. Majority of interns who participated in study were aware of the concept of rational use of medicine but the knowledge related to EML (essential medicines list), P drugs, schedule H drugs and number of FDCs (fixed dose combination) in EML was limited.

Conclusions:  As interns are future prescribers, they need to be aware of all the aspects of rational use of medicine and there is need to emphasise on learning module and training programs to ensure the interns have knowledge of rational use of medicines.


Rational use of medicines, Essential medicines list, Fixed dose combination

Full Text:



World Health Organization: Selection and rational use of medicines. Available from: factsheets/fs338/en/. Accessed on 20 December 2020.

The Role of Education in the Rational use of medicines. SEARO Technical Publication Series No. 4 World Health Organization, Regional Office for South-East Asia. Available at: Accessed on 20 December 2020

Susheela F, Goruntla N, Bhupalam PK, Veerabhadrappa KV, Sahithi B, Ishrar SMG. Assessment of knowledge, attitude, and practice toward responsible self-medication among students of pharmacy colleges located in Anantapur district, Andhra Pradesh, India. J Educ Health Promot. 2018;7:96.

Hooli TV, Srikanth, Somashekara SC, Suraj B. Knowledge, attitude, practice of rational use of medicines among junior residents in a tertiary care hospital. Int J Basic Clin Pharmacol. 2017;6:2001-4.

Rational use of drugs-Report of the Conference of Experts Nairobi. 1985.

Holloway K. Promoting rational use of medicines. Contact a publication of world council of churches. 2006;183:2-3.

Lawshe CH. A quantitative approach to content validity. Personnel psychol. 1975;28(4):563-75.

The Selection of Essential Medicines-Perspectives WHO policies. 2002;1-6.

Manikandan S, Gitanjali B. National list of essential medicines of India: The way forward. J Postgr Med. 2012;58(1):68-72.

De Vries TP, Henning RH, Horgerzeil HV, Fresle HV. World Health Organization: Guide to good prescribing. Geneva, WHO. 1994;14-8.

Sontakke SD, Budania RJ, Paranjape SG. Evaluation of knowledge, attitude and behavior about rational use of medicines in second year medical students. IJBCP. 2013;2(5):617-21.

Aronson JK. A prescription for better prescribing. Br J Clin Pharmacol. 2006;61(5):487-91.

Mahajan R, Singh NR, Singh J, Dixit A, Jain A, Gupta A. Current scenario of attitude and knowledge of physicians about rational prescription: A novel crosssectional study. J Pharm Bioalln Sci. 2010;2(2):132-6.

Kar SS, Pradhan HS, Mohanta G. Concept of Essential Medicines and Rational Use in Public Health. Indian J Community Med. 2010;35(1):10-3.

Hogerzeil HV. The concept of essential medicines: lesson for rich countries. BMJ. 2004;329:(7475)1169-72.

Rathod R, Rathod A, Gupta VK, Ahmed T, Jha RK, Gaikwad N. Audit in Dermatology for Rational Prescribing. RJPBCS. 2012;3(3):518-24.

The selection and use of Essential Medicines-Report of the WHO expert committee. Geneva, WHO. 2011. Available at: publications/essentialmeds_committeereports/en/. Accessed on 20 December 2020.