Fixed drug eruption associated with fixed combination of fluoroquinolone-nitroimidazole

Authors

  • R. Meenakshi Department of Pharmacology, Sri Manakula Vinayagar Medical college and Hospital, Pondicherry, India http://orcid.org/0000-0002-5744-5938
  • S. Nitya Department of Pharmacology, Sri Manakula Vinayagar Medical college and Hospital, Pondicherry, India
  • S. Kiruthika Department of Pharmacology, Sri Manakula Vinayagar Medical college and Hospital, Pondicherry, India
  • M. Shanthi Department of Pharmacology, Sri Manakula Vinayagar Medical college and Hospital, Pondicherry, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20211656

Keywords:

FDE, ciprofloxacin, Tinidazole

Abstract

Fixed drug eruptions (FDE) are cutaneous adverse drug reaction characterized by well demarcated erythematous plaques which on removal of the offending agent resolves with residual hyperpigmentation patches at the site. FDE to nitroimidazoles and fluoroquinolones have nevertheless been infrequently reported. Awareness about the adverse reaction to the fluoroquinolone-nitroimidazole combination drug and also the likelihood of recurrence with same or similar drugs and the possible cross reaction is eminent. Hereby we report one such case of FDE to ciprofloxacin/tinidazole combination.

Author Biographies

R. Meenakshi, Department of Pharmacology, Sri Manakula Vinayagar Medical college and Hospital, Pondicherry, India

Postgraduate,

Departmwnt of Pharmacology

S. Nitya, Department of Pharmacology, Sri Manakula Vinayagar Medical college and Hospital, Pondicherry, India

Associate Professor,
Department of Pharmacology.

S. Kiruthika, Department of Pharmacology, Sri Manakula Vinayagar Medical college and Hospital, Pondicherry, India

Professor & HOD,
Department of Pharmacology.

References

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Mithari HS, Gole PV, Kharkar VD, Mahajan SA. Generalized Bullous Fixed Drug Eruption to Fluconazole; with Cross-Reactivity to Tinidazole. Indian J Dermatol. 2019;64(4):335-7.

Sahoo, Himanshu, Panda, Abinash, Rath, Bandana. The unseen story of Tinidazole: Alarm to the drug regulatory bodies. MOJ Clin Med Care Rep. 2015;00007.

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Published

2021-04-26

How to Cite

Meenakshi, R., Nitya, S., Kiruthika, S., & Shanthi, M. (2021). Fixed drug eruption associated with fixed combination of fluoroquinolone-nitroimidazole. International Journal of Basic & Clinical Pharmacology, 10(5), 576–577. https://doi.org/10.18203/2319-2003.ijbcp20211656

Issue

Section

Case Reports