Assessment of drug utilization pattern and impact of infographics in patients with chronic liver disease
Keywords:CLD, Child, MELD, Diabetes mellitus
Background: The current study was conducted to ensure that the drugs were effectively utilised and also to create awareness and knowledge by providing counselling with the help of infographics among study population.
Methods: A prospective interventional study was conducted in the gastroenterology department of a tertiary care hospital in Kerala. A total of 100 patients diagnosed with chronic liver disease (CLD) were enrolled for the study and data were recorded in a predesigned pro forma. Statistical analysis (paired t test) was performed to assess whether the drug has been effectively utilized in patients. The study population was counselled with the help of infographics and its impact was assessed from the questionnaire, which was set based on 5- point Likert’s scale.
Results: Among 100 patients, males are more prevalent between the age groups 60-70. Diabetes mellitus (DM) (66%) and alcohol (37%) are the most common risk factors. Most of the study subjects belong to Child A (50%) category and model for end-stage liver disease (MELD) score of 51% of the patients were ≤9 with estimated 3-month mortality rate of 1.9%. Liver function tests (LFT) had shown that there was a significant difference between prior to and after treatment with the level of significance p<0.05, indicating that the drugs had been properly utilized in patients and found to be effective. The distributed infographics had a great impact among the study population.
Conclusions: The study concluded that the drugs had been properly utilized and found to be effective in patients. The Infographics showed a positive impact among the study population.
Introduction to drug utilization research. Geneva: World Health Organization. 2003. Available at: file:///C:/Users/admin/Downloads/924156234X.pdf. Accessed on 10 December 2020.
Ashok P, Subramanian V. Importance of Drug Utilization Evaluation Studies in Patient Health Care. Indian J Pharmacy Practice. 2017;10(3):157-9.
Gama H. Drug Utiliz5ation Studies. Arquivos De Medicina. 2007;22:6.
Kerala Medical Services Corporation Ltd. Available at: http://www.kmscl.kerala.gov.in/category.php?slug=EDL. Accessed on 10 December 2020.
Liver disease-an emerging silent epidemic in Kerala-Kaumudi global Daily Hunt. 2018. Available at: https://m.dailyhunt.in/news/india/english/kaumudiglobalepaper-kglobal/liver+disease+an+emerging+silent+epidemic+in+kerala-newsid87087051. Accessed on 10 December 2020.
Balkac M, Ergun E. Role of Infographics in Healthcare. Chinese Med J. 2018;131(20):2514-7.
Mohan H. Textbook of Pathology; 7th edition. New Delhi: Jaypee Brothers Medical Publishers, The Health Science Publisher. 2015;603-11.
Koda-Kimble M, Katcher B, Young L. Applied therapeutics for clinical pharmacists. 7th ed. San Francisco: Applied Therapeutics. 1978;27.
Frith J, Jones D, Newton J. Chronic liver disease in an ageing population. Age and Ageing. 2008;38(1):11-8.
Zeebaish S, Hemalatha P, Eswari PVSN, Kodandaraman T, Lakshmi P, Apoorva G. A prospective observational study on prescribing patterns of drugs used in alcoholic liver disease patients at tertiary care teaching hospital. Int J Basic Clin Pharmacol. 2017;6(6):1386-92.
Arathy PC, Mohan V, Al-Muneer S, Dhanya H. A prospective observational study on pattern of comorbid conditions in CLD patients with drug use pattern, and assessment of severity using meld score. Indian res j pharmacy res. 2016;11:861-7.
Sharma B, Marwah R, Raina S, Sharma N, Kaushik M, Singh Kaushal S. A study on the etiology of cirrhosis of liver in adults living in the Hills of Himachal Pradesh, India. Topical Gastroenterol. 2016;37(1):37-41.