DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20201182

The short and long-term impact of educational intervention on pharmacovigilance awareness in second year MBBS students: a questionnaire-based survey

Lavanya S. Honnagangadevaru, Kalpana Lakshmanegowda

Abstract


Background: Under-reporting of adverse drug reactions (ADRs) is a burning issue globally. Sensitizing medical students to the concepts of pharmacovigilance in their early years through regular training holds the key for successfully perpetuating ADR reporting culture. This study attempted to assess the short and long-term impact of interventional training programs on the knowledge and perception of Pharmacovigilance amongst II MBBS students.

Methods: It was a Cross-sectional, interventional, questionnaire‑based study. Second MBBS, new entrants (n=127) were tested for their awareness regarding pharmacovigilance knowledge using pre-validated questionnaires at entry point and following regular training sessions, at 1 week (short-term) and at 1 year (long-term). Students’ perceptions towards ADR monitoring were also recorded. Descriptive statistics, Chi-square test, Independent t-test/Mann-Whitney-U test for identifying mean difference and paired-t-test/Wilcoxon signed rank test for paired data was used for quantitative and qualitative data analysis accordingly.

Results: Significant improvement in scores following training was seen at both short (10.8±1.914) and long term (11.63±1.516) compared to base-line scores (6.07±2.036). There was significant increase in long-term scores compared to short-term scores (<0.001). Female students performed better than their male counterparts. Majority of students positively perceived the need for ADR monitoring and reporting.

Conclusions: Pharmacovigilance training increases students’ knowledge significantly. Strengthening the existing pharmacovigilance activities through regular refresher training programs and adequate sequencing in curriculum not only maintains but improves students’ knowledge significantly.


Keywords


Awareness, Educational intervention, Impact, Pharmacovigilance, Short and long-term

Full Text:

PDF

References


Sattigeri BM, Moorthy V. Pharmacovigilance: Its clinical implications in health care management. J Integr Health Sci. 2014;2:33-5.

World Health Organization. Quality Assurance and Safety of Medicines Team. (‎2006)‎. The safety of medicines in public health programmes: pharmacovigilance, an essential tool. World Health Organization. Available from: https://apps.who.int/ iris/handle/10665/43384. Accessed on 31 October 2019.

Lopez-Gonzalez E, Herdeiro MT, Figueiras A. Determinants of under-reporting of adverse drug reactions: a systematic review. Drug Safety. 2009;32(1):19-31.

Singh J, Singh H, Rohilla R, Kumar R, Gautam CS. Lack of awareness of pharmacovigilance among young health-care professionals in India: An issue requiring urgent intervention. Int J Appl Basic Med Res. 2018;8(3):158-63.

Gupta SK, Nayak RP, Shivaranjani R, Vidyarthi SK. A questionnaire study on the knowledge, attitude, and the practice of pharmacovigilance among the healthcare professionals in a teaching hospital in South India. Perspect Clin Res. 2015;6:45-52.

Rehan HS, Sah RK, Chopra D. Comparison of knowledge, attitude and practices of resident doctors and nurses on adverse drug reaction monitoring and reporting in a tertiary care hospital. Indian J Pharmacol. 2012;44:699-703.

Ganesan S, Sandhiya S, Reddy KC, Subrahmanyam DK, Adithan C. The impact of the educational intervention on knowledge, attitude, and practice of pharmacovigilance toward adverse drug reactions reporting among health-care professionals in a tertiary care hospital in South India. J Nat Sci Biol Med. 2017;8(2):203-9.

Arici MA, Gelal A, Demiral Y, Tuncok Y. Short and long-term impact of pharmacovigilance training on the pharmacovigilance knowledge of medical students. Indian J Pharmacol. 2015;47(4):436-9.

Kamuche, FU, Ledman RE. Relationship of time and learning retention. J Coll Teach Learn. 2005;2(8):25-8.

Fisher J, Viscusi R, Ratesic A, Johnstone C, Kelley R, Tegethoff AM, et al. Clinical skills temporal degradation assessment in undergraduate medical education. J Adv Med Educ Prof. 2018;6(1):1-5.

Semb GB, Ellis JA. Knowledge taught in school: What is remembered? Rev Educ Res. 1994;64:253-86.

Othman GQ, Ibrahim MIM, Alshakka M, Ansari M, Al-Qadasi F, Halboup AM. Knowledge and perception about pharmacovigilance among pharmacy students of universities in Sana'a Yemen. J Clin Diagn Res. 2017;11(6):FC09-13.

Loprinzi PD, Frith E. The Role of sex in memory function: considerations and recommendations in the context of exercise. J Clin Med. 2018;7(6).

Torwane NA, Hongal S, Gouraha A, Saxena E, Chavan K. Awareness related to reporting of adverse drug reactions among health caregivers: A cross-sectional questionnaire survey J Nat Accred Board Hosp Healthcare Providers. 2015;2:23-9.

Bharadwaj V, Budania N, Mondal, Yadav V, Sharma P. A survey to assess the awareness of adverse drug reactions and pharmacovigilance practices among healthcare professionals in a tertiary care hospital. Int J Med Res Prof. 2016;2(1):134-7.