A case report of drug rash with eosinophilia and systemic symptoms syndrome induced by dapsone

Authors

  • Swathy A. R. Department of Pharmacology, Karnataka Institute of Medical Science, Hubbali, Karnataka, India
  • A. N. Dattatri Department of Pharmacology, Karnataka Institute of Medical Science, Hubbali, Karnataka, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20201195

Keywords:

Dapsone, Dapsone hypersensitivity syndrome, DRESS syndrome

Abstract

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a distinct, severe, idiosyncratic reaction to a drug characterized by a prolonged latency period. It is followed by a variety of clinical manifestations, usually fever, rash, lymphadenopathy, eosinophilia, and a wide range of mild-to-severe systemic presentations. Among sulfonamides, Dapsone, sulfamethoxazole-trimethoprim and sulfasalazine are the most common offending drugs. We report here a case of DRESS syndrome due to dapsone.

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Author Biographies

Swathy A. R., Department of Pharmacology, Karnataka Institute of Medical Science, Hubbali, Karnataka, India

Department of Pharmacology 

post graduate student(doctor)

A. N. Dattatri, Department of Pharmacology, Karnataka Institute of Medical Science, Hubbali, Karnataka, India

Department of Pharmacology

Head of Department

References

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Published

2020-03-24

How to Cite

A. R., S., & Dattatri, A. N. (2020). A case report of drug rash with eosinophilia and systemic symptoms syndrome induced by dapsone. International Journal of Basic & Clinical Pharmacology, 9(4), 657–659. https://doi.org/10.18203/2319-2003.ijbcp20201195

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Section

Case Reports