Ertugliflozin: a novel anti-diabetic drug

Vikrant Sharma; Sonika Sharma; Sanjay Jaiswal; Ravi R. Ghanghas; Durgaprasad Bodepalli; Ashok Kumar Sharma

doi:10.18203/2319-2003.ijbcp20184607

Authors

Vikrant Sharma Department of Pharmacology, Armed Forces Medical College (AFMC). Pune, Maharashtra, India
Sonika Sharma Department of Pharmacology, Armed Forces Medical College (AFMC). Pune, Maharashtra, India
Sanjay Jaiswal Department of Pharmacology, Armed Forces Medical College (AFMC). Pune, Maharashtra, India
Ravi R. Ghanghas Department of Pharmacology, Armed Forces Medical College (AFMC). Pune, Maharashtra, India
Durgaprasad Bodepalli Department of Pharmacology, Armed Forces Medical College (AFMC). Pune, Maharashtra, India
Ashok Kumar Sharma Department of Pharmacology, Armed Forces Medical College (AFMC). Pune, Maharashtra, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20184607

Keywords:

Diabetes mellitus, Ertugliflozin, SGLT2 inhibitor

Abstract

Diabetes Mellitus is a disorder of global proportion. Despite various treatment modalities presently being available, yet the desired glycaemic control and patient outcomes have not been achieved completely. Sodium glucose co-transporter type 2 inhibitors (SGLT2 inhibitors) are one such promising group of emerging drugs in diabetes treatment. Ertugliflozin prevents the reabsorption of glucose by inhibiting sodium-glucose cotransporter-2 (SGLT2) at proximal convoluted tubules. Ertugliflozin is available as 5mg and 15mg tablets. Ertugliflozin has been related to genital mycotic infections and urinary tract infections. Benefits of Ertugliflozin include better control on blood glucose, body weight and blood pressure.

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