Published: 2018-07-23

Angioedema caused by over the counter use of dicyclomine hydrochloride and paracetamol fixed dose combination in a child: a case report

Latesh B. Raghute, Sujata Dudhgaonkar, Kavita M. Jaiswal, Akhilesh Singh Parihar, Swapna M. Bhalerao, Sagrika R. Jumle


Authors describe a case of angioedema in a male child due to over-the-counter (OTC) use of fixed dose combination (FDC) of Tab. dicyclomine hydrochloride (20mg) and paracetamol (500mg) for abdominal pain. Use of OTC drugs in children without a doctor’s suggestion can lead to unnecessary medication use and is not free of risks. Here, there is a probable causal relationship between the suspected drug and angioedema according to WHO-UMC criteria for Causality Assessment. This case was also reported to the Pharmacovigilance Programme of India (PvPI) through PvPI ADR android application.


Angioedema, Dicyclomine hydrochloride, Over-the-counter drugs, Paracetamol

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