Angioedema caused by over the counter use of dicyclomine hydrochloride and paracetamol fixed dose combination in a child: a case report

Latesh B. Raghute; Sujata Dudhgaonkar; Kavita M. Jaiswal; Akhilesh Singh Parihar; Swapna M. Bhalerao; Sagrika R. Jumle

doi:10.18203/2319-2003.ijbcp20183040

Authors

Latesh B. Raghute Department of Pharmacology, Government Medical College Gondia, Gondia, Maharashtra, India
Sujata Dudhgaonkar Department of Pharmacology, Government Medical College Gondia, Gondia, Maharashtra, India
Kavita M. Jaiswal Department of Pharmacology, Government Medical College Gondia, Gondia, Maharashtra, India
Akhilesh Singh Parihar Department of Pharmacology, Government Medical College Gondia, Gondia, Maharashtra, India
Swapna M. Bhalerao MBBS Student, Government Medical College Gondia, Gondia, Maharashtra, India
Sagrika R. Jumle MBBS Student, Government Medical College Gondia, Gondia, Maharashtra, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20183040

Keywords:

Angioedema, Dicyclomine hydrochloride, Over-the-counter drugs, Paracetamol

Abstract

Authors describe a case of angioedema in a male child due to over-the-counter (OTC) use of fixed dose combination (FDC) of Tab. dicyclomine hydrochloride (20mg) and paracetamol (500mg) for abdominal pain. Use of OTC drugs in children without a doctor’s suggestion can lead to unnecessary medication use and is not free of risks. Here, there is a probable causal relationship between the suspected drug and angioedema according to WHO-UMC criteria for Causality Assessment. This case was also reported to the Pharmacovigilance Programme of India (PvPI) through PvPI ADR android application.

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