Drug prescribing pattern in surgical wards of a tertiary care hospital in Western part of India
Keywords:Drug utilization study, Drug use indicator, Surgical ward
Background: In surgical wards, drugs are required to manage pain, nausea, vomiting, infections, etc. A growing number of pharmaceutical products are available in present era. Irrational prescribing of drugs is prevalent worldwide. Drug utilization study can be used to assess prescribing patterns. Authors undertook this study to determine current practice of prescribing in surgical wards of the hospital.
Methods: Authors conducted observational, noninterventional, descriptive study among patients admitted in surgical wards for one year. Authors have analysed collected data of 604 patients using descriptive statistics to determine utilization pattern of drugs and drug use indicators.
Results: Appendicitis (14.9%) followed by hernia (10.6%) were leading diseases for admission. Mean duration of stay was 7.44. Average number of drugs in a prescription was 8.94. Antibiotics (32.07 %), analgesics (17.11 %) and antacids (16.09 %) were leading drug groups prescribed. Amikacin (5.81 %) followed by metronidazole (5.30 %) and ciprofloxacin (5.19 %) were commonly prescribed antimicrobial drugs. Tramadol (5.31 %) and pantoprazole (7.17 %) were leading drugs prescribed from analgesics and antacids respectively. All prescriptions had at least one injectable drug. At least one antibiotic was present in 92.05 % prescriptions. Majority of drugs (87.27 %) were prescribed by generic names. Proportion of drugs prescribed from essential medicine list was 84.22 %.
Conclusions: Polypharmacy and injectable drug prescribing were common in practice. There is a scope for improving such prescribing practices among practitioners. Use of multiple antibiotics should be avoided whenever possible and usage should be evidence based.
World Health Organization. Introduction to Drug Utilization Research. Geneva: World health organization; 2003.
World Health Organization. Promoting rational use of medicines: core components. Geneva: World health organization; 2002.
Raveh D, Levy Y, Schlesinger Y, Greenberg A, Rudensky B, Yinnon AM. Longitudinal surveillance of antibiotic use in the hospital. Q J Med 2001;94:141-52.
Bhabhor P, Hotchandani H. An Antibacterial Drug Utilization Study at Surgical Units of Shree Sayaji General Hospital, Vadodara, Gujarat, India. The Internet J Pharmacol. 2012;10:2/16.
Salman MT, Akram MF, Rahman S, Khan FA, Haseen MA, Khan SW. Drug prescribing pattern in surgical wards of a teaching hospital in North India. Ind J the Practis Doc. 2008;5(2):5-8.
Ministry of Health and Family Welfare Government of India. National List of Essential Medicines; 2015. Available at: http://cdsco.nic.in/WriteReadData/NLEM-2015/NLEM,%202015.pdf. Accessed 20 October 2016.
Sharma N, Bhargava M, Chaudhary V, Advani U, Jain A, Bansal A. A prospective study of drug utilization pattern in surgery department in a tertiary care teaching hospital in Rajasthan. UJP 2014;03(02):47-50.
Bhansali NB, Gosai TR, Dholaria NK, Suthar SD, Chacko J, Chavda DA, et al. Drug utilization study in post-operative patients in surgical ward of a tertiary hospital attached with medical college. Der Pharmacia Lettre. 2013;5(1):251-7.
Venkateswarlu B, Swapna Y, Florence S, Lakshmi Santoshi M, Swetha T, Prathyusha K, et al. Drug utilization study of antibiotics in surgical ward of a tertiary care hospital. Inte J Chem and Pharmaceu Scienc. 2015;6(1):106-13.
Patil S, Padma L, Veena DR, Shanmukananda P. Drug utilization study of antimicrobials in post-operative wards in a teaching hospital. Int Res J Pharm App Sci. 2012;2(5):56-9.
Khade A, Bashir M, Sheethal A. Prescription Pattern in the Department of Surgery in A Tribal District Hospital of Andhra Pradesh, India. Ann Med Health Sci Res 2013;3(3):438-41.
Kumar BA, Adiveni T, Manna PK, Kumar M, Sundresh D. Studies on antibiotic prescribing pattern in surgical ward of department of surgery at rajah muthiah medical college hospital. World J Pharma and Pharmaceut Scien. 2014;3(7):832-71.
Mondal S, Pramani S, Mallick B, Sengupta M, Niyogi S, Chaudhuri P. A Drug Utilization Study in the Indoor Ward of the Surgery Department of a Tertiary Care Hospital of Eastern India. IOSR J Den and Med Scienc. 2015:14(10):42-7.
Vadajiya S, Naik V, Mevada A. A Study of Anti-Microbial Drug Utilization Pattern and Appropriateness in The Surgical Units of Civil Hospital, Ahmedabad; Int J Pure App Biosci. 2014;2(3):77-82.
Chaturvedi S, Chaturvedi A. Postoperative pain and its management. Indian J Crit Care Med. 2007;11:204-11.
Gyawali S, Shankar PR, Saha A, Mohan L. Study of prescription of injectable drugs and intravenous fluids to inpatients in a teaching hospital in Western Nepal. MJM. 2009;12:13-20.
Sharma N, Bhargava M, Mahawar D, Paeakh R, Sharma D. Usage of Antibiotics in postoperative patients in tertiary care teaching hospital in India. IJPRB. 2014;3(2):99-105.
Mohammed SS, Sreenath MK, Vishnu VG, Jose F, Siraj ST, Anand VP. The Prevalence of Polypharmacy in South Indian Patients: A Pharmacoepidemiological Approach. Ind J Pharma Practi. 2012;5(3):40-4.