Assessment of knowledge about post exposure prophylaxis of HIV among medical, nursing and paramedical students in hospital and laboratory practice

Authors

  • Dulcie Celia A. Department of Pharmacology, Tirunelveli Medical College, Tirunelveli, Tamilnadu, India
  • Mohamed Thajudeen S. Department of Pharmacology, Tirunelveli Medical College, Tirunelveli, Tamilnadu, India
  • Meenakshi B. Department of Pharmacology, Tirunelveli Medical College, Tirunelveli, Tamilnadu, India
  • Ezhil Ramya J. Department of Pharmacology, Tirunelveli Medical College, Tirunelveli, Tamilnadu, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20174368

Keywords:

HIV, Knowledge, Post exposure prophylaxis (PEP), Students

Abstract

Background: India has 2.1 million of people living with HIV, and places in third-largest population of people infected with the HIV after South Africa and Nigeria. It is thus important for health care providers including medical, nursing and paramedical students to have adequate knowledge on PEP for HIV to protect themselves prior to starting their life long career.

Methods: Cross-sectional study was conducted among 200 medical, nursing and paramedical students in Tirunelveli medical college from December 2016 to February 2017. A pre-designed questionnaire was used to collect data. Results were summarized in percentages and presented in tables.

Results: A total of 96 (48%) males and 104 (52%) females responded in the study. Though many (87%) had heard about PEP, just 31 (15.5%) had received formal training on PEP for HIV. Only 81 (40.5%) knew the ideal PEP regimen and 88 (44%) knew the correct drug regimen. The majority 196 (98%) considered PEP was important and significant 178 (89%) considered themselves to be at risk of acquiring HIV at work, with 46 (23%) having experienced an exposure in the past. Of those exposed, only 21 (45.7%) received PEP.

Conclusions: This study shows that knowledge, attitude and practice towards PEP for HIV is inadequate. A formal PEP training centre with proper guidelines is recommended for medical, nursing and paramedical students.

References

Sultan B, Benn P, Waters L. Current perspectives in HIV post-exposure prophylaxis. HIV/AIDS (Auckland, NZ). 2014;6:147.

Pinto LA, Landay AL, Berzofsky JA, Kessler HA, Shearer GM. Immune response to human immunodeficiency virus (HIV) in healthcare workers occupationally exposed to HIV-contaminated blood. The American journal of medicine. 1997 May 19;102(5):21-4.

Spira AI, Marx PA, Patterson BK, Mahoney J, Koup RA, Wolinsky SM, et al. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. Journal of Experimental Medicine. 1996 Jan 1;183(1):215-25.

Miller RJ, Cairns JS, Bridges S, Sarver N. Human immunodeficiency virus and AIDS: insights from animal lentiviruses. Journal of virology. 2000 Aug 15;74(16):7187-95.

Otten RA, Smith DK, Adams DR, Pullium JK, Jackson E, Kim CN, et al. Efficacy of postexposure prophylaxis after intravaginal exposure of Pig-tailed macaques to a human-derived retrovirus (human immunodeficiency virus type 2). J Virol. 2000;74(20):9771-5.

Cardo DM, Culver DH, Ciesielski CA, Srivastava PU, Marcus R, Abiteboul D, et al. A case–control study of HIV seroconversion in health care workers after percutaneous exposure. N Engl J Med. 1997;337(21):1485-90.

Mathewos B, Birhan W, Kinfe S, Boru M, Tiruneh G, Addis Z, et al. Assessment of knowledge, attitude and practice towards post exposure prophylaxis for HIV among health care workers in Gondar, North West Ethiopia. BMC Public Health. 2013;13(1):508.

Owolabi RS, Alabi P, Ajayi S, Daniel O, Ogundiran A, Akande TM, et al. Knowledge and practice of post-exposure prophylaxis (PEP) against HIV infection among health care providers in a tertiary hospital in Nigeria. J Int Assoc Physicians AIDS Care Chic Ill 2002. 2012;11(3):179-83.

Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, et al. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis. Infect Control Hosp Epidemiol. 2013;34(9):875-92.

Tebeje B, Hailu C. Assessment of HIV post-exposure prophylaxis Use among health workers of governmental health institutions in JIMMA zone, oromiya region, Southwest Ethiopia. Ethiop J Health Sci. 2010;20(1):55-64.

Ajibola S, Akinbami A, Elikwu C, Odesanya M, Uche E. Knowledge, attitude and practices of HIV post exposure prophylaxis amongst health workers in Lagos University Teaching Hospital. Pan Afr Med J. 2014;19:172.

Lamichanne J, Aryal B, Dhakal KS. Knowledge of nurses on post exposure prophylaxis of HIV in medical colleges of chitwan district, Nepal. Int J Pharm Biolog Arch. 2012;3(6):1394-9.

Aminde LN, Takah NF, Dzudie A, Bonko NM, Awungafac G, Teno D, et al. Occupational Post-Exposure Prophylaxis (PEP) against Human Immunodeficiency Virus (HIV) infection in a health district in Cameroon: assessment of the knowledge and practices of nurses. PLoS One. 2015;10(4):e0124416.

Esin IA, Alabi S, Ojo E, Ajape AA. Knowledge of human immunodeficiency virus post-exposure prophylaxis among doctors in a Nigerian tertiary hospital. Niger J Clin Pract. 2011;14(4):464-6.

Agaba PA, Agaba EI, Ocheke AN, Daniyam CA, Akanbi MO, Okeke EN. Awareness and knowledge of human immunodeficiency virus post exposure prophylaxis among Nigerian family physicians. Niger Med J J Niger Med Assoc. 2012;53(3):155-60.

Nwanko TO, Aniebue UU. Percutaneous injuries and accidental blood exposure in surgical residents: Awareness and use of prophylaxis in relation to HIV. Niger J Clin Pract. 2011;14:34-7.

Sendo EG. Assessment of level of knowledge and practice of nursing and midwifery students on HIV post exposure prophylaxis in hawassa university Ethiopia. J HIV Clin Sci Res. 2014;1:101.

Chacko J, Isaac R. Percutaneous injuries among medical interns and their knowledge and practice of post exposure prophylaxis for HIV. Indian J Public Health. 2007;51:127-9.

Kasat V, Saluja H, Ladda R, Sachdeva S, Somasundaram K, Gupta A. Knowledge, attitude and practices toward post exposure prophylaxis for human immunodeficiency virus among dental students in India. Ann Med Health Sci Res. 2014;4(4):543-8.

HIV/AIDS. World Health Organization. Available at: http://www.who.int/mediacentre/factsheets/fs360/en/. Accessed 3 February 2017.

Post Exposure Prophylaxis (PEP). National AIDS Control Organization. Available at: http://www.naco.gov.in/NACO/National_AIDS_Control_Program/Services_for Prevention/ PEP/. Accessed 3 February 2017.

Mesfin YM, Kibret KT. Assessment of knowledge and practice towards hepatitis B among medical and health science students in Haramaya University. Ethiopia PloS One. 2013;8(11):e79642.

Mathewos B, Birhan W, Kinfe S, Boru M, Tiruneh G, Addis Z, et al. Assessment of knowledge, attitude and practice towards post exposure prophylaxis for HIV among health care workers in Gondar, North West Ethiopia. BMC Public Health. 2013;13:508.

Aggarwal V, Seth A, Chandra J, Gupta R, Kumar P, Dutta AK. Occupational exposure to human immunodeficiency virus in health care providers: a retrospective analysis. Indian J Community Med. 2012;37(1):45-9.

UNAIDS. 2015 AIDS Epidemic Update; Available at: http://www.aidsdatahub.org/Country-Profiles/India. Accessed 3 February 2017.

Gupta A, Anand S, Sastry J, Krisagar A, Basavaraj A, Bhat SM, et al. High risk for occupational exposure to HIV and utilization of post-exposure prophylaxis in a teaching hospital in Pune. India BMC Infect Dis. 2008;8(1):142.

Tebeje B, Hailu C. Assessment of HIV Post-Exposure Prophylaxis use Among Health Workers of Governmental Health Institutions in Jimma zone, Oromiya Region, Southwest Ethiopia. Ethop J Health Sci. 2010 Mar;20(1):55-64.

Karen B, Helen H, Warren P, Zinhle N. 2004. Post-Exposure Prophylaxis (PEP) in South Africa: Analysis of Calls to the National AIDS Help line. Available online at www.cadre.org.za. Accessed 3 February 2017.

Chen YM, Fox E, Rogers AC. Post exposure prophylaxis for human immunodeficiency virus: knowledge and experience of junior doctors. Sexually Transm. Infect. 2001;77:444-5.

Gurubacharya DL, Mathura KC, Karki DB. Knowledge, attitude and practices among health care workers on needle-stick injuries. Kathmandu Univ Med J. 2003;1(2):91-4.

Karstaedt AS, Pantanowitz L. Occupational exposure of interns to blood in an area of high HIV seroprevalence. S Afr Med J. 2001;91(1):57-61.

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Published

2017-09-23

How to Cite

A., D. C., S., M. T., B., M., & J., E. R. (2017). Assessment of knowledge about post exposure prophylaxis of HIV among medical, nursing and paramedical students in hospital and laboratory practice. International Journal of Basic & Clinical Pharmacology, 6(10), 2408–2413. https://doi.org/10.18203/2319-2003.ijbcp20174368

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Original Research Articles