Community acquired urinary tract infection in pediatric age-group with changing trends of antibiotic resistance pattern over 3 years: a clinico-epidemiological study


  • Baishali Chakroborty Department of Microbiology, Calcutta Medical College, Kolkata, West Bengal, India
  • Sumanta Kumar Dutta Department of ENT, Calcutta National Medical College, Kolkata, West Bengal, India
  • Patralekha Ray Chaudhuri Department of Pharmacology, Calcutta National Medical College, Kolkata, West Bengal, India
  • Ranjita Santra(Dhali) Department of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, West Bengal, India


Urinary tract infection, Pediatric population, Antibiotic resistance, Empirical treatment


Background: Assessment of the antimicrobial sensitivity pattern in urinary isolates of the children suffering from urinary tract infection (UTI) and evaluation of the recent trends of multi-drug resistance in the isolates. The aim was to find out the antibiotics sensitivity of the organisms isolated from the urine samples of pediatric age-group with emphasis on their resistance pattern.

Methods: A clinico-epidemiological study comprising of 304 specimens of urine were collected among all the children with UTI below 12 years of age, attending pediatric outpatient department of a tertiary care teaching hospital in eastern India wet mount microscopy and semi quantitative culture were done to diagnose UTI. Organisms isolated were identified by standard biochemical tests, and antibiogram studies were done by standard Kirby-Bauer disc diffusion test statistical analysis, Microsoft excel and SPSS were used for analysis of data.

Results: Aminoglycosides had wider sensitivity pattern toward most of the uropathogens whereas tetracyclines and co-amoxyclav in particular were resistant for most of the organisms. Among all the organisms, Pseudomonas and Enterococcus species showed higher resistance pattern toward the conventional antimicrobials.

Conclusions: The changing trends in the anti-biograms of several Gram-positive and Gram-negative microorganisms in UTI demands reconsideration with respect to rational drug use in the pediatric age group.


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How to Cite

Chakroborty, B., Dutta, S. K., Chaudhuri, P. R., & Santra(Dhali), R. (2017). Community acquired urinary tract infection in pediatric age-group with changing trends of antibiotic resistance pattern over 3 years: a clinico-epidemiological study. International Journal of Basic & Clinical Pharmacology, 4(1), 30–35. Retrieved from



Original Research Articles