DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20150046

A quasi-experimental study to assess the effect of a local anesthetic proparacaine on tropicamide-induced pupillary dilation

Jayashree Padmaraj Menishinkai, Chaitra Pujar, C. N. Manasa, Laxman V. Dasar, Mallikarjun C. Salagar

Abstract


Background: Dilating the pupil is one of the most commonly practiced methods among ophthalmologists to examine the eye especially the posterior segment of the eye. Here we conducted a study to know the clinical effect of proparacaine, a local anesthetic, on tropicamide-induced pupillary dilation.

Methods: A Quasi-experimental study was conducted on 57 subjects aged between 20 and 70 years. Study was done over a period of 3 months (February 14 - April 14) at a tertiary health care center in Bagalkot after obtaining institutional ethical committee clearance. Proparacaine was instilled in one eye (right eye) before instilling tropicamide and the other eye with a placebo (normal saline). Pupil diameter was measured using a pupillary gauge at 0, 15, and 30 mins. Results were analyzed using unpaired Student’s t-test.

Results: The mean clinically efficient pupillary diameter at the end of 15 mins in proparacaine instilled eye was 5.56±0.5 and in control eye was 5.25±0.45 mm with t value 8.13 (p<0.001) which was statistically significant. And at the end of 30 mins pupillary diameter in the study group was 7.96±0.43 mm and in the control group was 7.83±0.43 mm with t value of 4.115 (p<0.001) which was also statistically significant.

Conclusions: Therefore, we do recommend the use of proparacaine before instilling tropicamide for faster pupillary dilation.


Keywords


Proparacaine, Pupillary dilation, Tropicamide, Clinically effective diameter

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