Exploring the efficacy of herbal toothpaste formulated with karanj, miswak and banana peel
DOI:
https://doi.org/10.18203/2319-2003.ijbcp20254158Keywords:
Karanj, Miswak, Antimicrobial, Banana peel, Herbal toothpaste, Oral health, Oral hygiene, Natural ingredientsAbstract
Background: Oral health is essential for maintaining overall well-being, as poor oral hygiene has been associated with various systemic diseases. Common issues such as halitosis, dental caries, and gum inflammation adversely affect quality of life. Conventional toothpastes often contain synthetic ingredients that may cause side effects, creating a growing need for natural alternatives. This study aimed to develop an herbal toothpaste using karanj (Millettia pinnata), miswak (Salvadora persica), and banana peel (Musa spp.), known for their antibacterial, anti-inflammatory, and antimicrobial properties.
Methods: Active compounds were extracted from the botanicals using standard solvent extraction techniques. The extracts were characterized for their phytochemical constituents and incorporated into a toothpaste base optimized for pH, stability, texture, and consistency. The antimicrobial activity of the formulation was tested against common oral pathogens, Staphylococcus aureus and Escherichia coli. Additionally, a sensory evaluation was conducted to assess taste and foaming ability.
Results: Phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, and phenolic compounds responsible for antimicrobial action. The herbal toothpaste exhibited significant antibacterial activity, showing inhibition zones comparable to some commercial formulations. Sensory evaluation results indicated favorable responses in terms of taste, texture, and overall satisfaction. The formulation remained stable in consistency and pH during the testing period.
Conclusions: The herbal toothpaste formulated demonstrated strong antimicrobial efficacy. This study supports the potential of plant-based ingredients as safe, cost-effective, and eco-friendly alternatives to synthetic oral care products, promoting sustainable and holistic oral hygiene.
Metrics
References
Petersen PE. The World Oral Health Report 2003: Continuous improvement of oral health in the 21st century- the approach of the World Health Organization. Community Dentist Oral Epidemiol. 2003;31(1):3-24.
Kassebaum NJ, Bernabé E, Dahiya M, Bhandari B, Murray CJ, Marcenes W. Global burden of severe tooth loss: a systematic review and meta-analysis. Journal of dental research. 2014;93(7_suppl):20S-8S.
Loesche WJ. Role of oral bacteria in the pathogenesis of periodontal disease. J Periodont Res. 2007:42(5):1-12.
Griffin SO, Jones JA, Brunson D, Griffin PM, Bailey WD. Burden of oral disease among older adults and implications for public health priorities. Am J Public Health. 2012;102:411-8.
Choo A, Delac DM, Messer LB. Oral hygiene measures and promotion: Review and considerations. Aust Dent J. 2001;46:166-73.
Chambrone LA, Chambrone L. Results of a 20-year oral hygiene and prevention programme on caries and periodontal disease in children attended at a private periodontal practice. Int J Dent Hyg. 2011;9:155-8.
Vajrabhaya L, Benjasupattananan S, Sappayatosok K, Dechosilpa V, Korsuwannawong S, Sirikururat P. Efficacy of a herbal toothpaste during active periodontal treatment: a clinical study. Dent J. 2024;12(12):378.
Jadhav J, Khan ZK. Formulation and evaluation of herbal toothpaste NCIM 3282. Int J Res Pub Rev. 2024;5:7795-801.
Lauten JD, Boyd L, Hanson MB. A clinical study: melaleuca, manuka, calendula and green tea mouth rinse. Phytother Res. 2005;19(11):951-8.
Mishra R, Tandon S, Rathore M, Banerjee M. Antimicrobial efficacy of probiotic and herbal oral rinses against Candida albicans in children: a randomized clinical trial. Int J Clin Pediatr Dent. 2016;9:25-30.
Pannuti CM, Mattos JP, Ranoya PN. Clinical effect of a herbal dentifrice on the control of plaque and gingivitis: a double-blind study. Pesqui Odontol Bras. 2003;17(4):314-22
Parabathina R, Varma K, Nikam G. Studies on formulation of herbal toothpaste from pongamia seeds and its medicinal evaluation. Int J Pharm Sci. 2024;2(12).
Amelia H, Febriani M, Rachmawati E. Potencial of various natural bleaching ingredients on teeth discoloration. J Adv Med Dent Sci Res. 2022;10(1):109-14.
Yudhit A, Prasetia W. Potency of banana (Musa paradisiaca var. Raja) peel extract as color changes agent of human teeth (in-vitro). J Dent Med Sci. 2019;18(10):68-71.
Alrabiah A, Albalawi F, Aljazea SA, Barri RM, Alquraishi SI, Alharthi A, et al. Effect of banana peels on dental bleaching: an in vitro study. Ann Dent Specialty. 2024;12(1-2024):21-5.
Thakur SH, Kaurav H, Chaudhary G. Karanj (Pongamia pinnata)- an ayurvedic and modern overview. Asian J Pharm Clin Res. 2021;14(6):86-92.
Sagar PK, Paliwal RK. Phytochemical screening and antioxidant potential of Pongamia pinnata (Vent) hydroalcoholic root and leaf extracts. Int J Nat Prod Sci. 2013;3(4):19-29.
Singh RK (2017). Anti inflammatory investigation of karanj oil isolated from Pongamia pinnata (seeds) in experimental animal models. World J Pharm Pharm Sci. 2017;l6(2):707-13
Rai M, Pandit R, Gaikwad S, Kövics G. Antibacterial activity of Karanj oil against cariogenic bacteria. J Essential Oil Res. 2011;23(5):51–5.
Dwivedi D, Dwivedi M, Malviya S, Singh V. Evaluation of wound healing, anti-microbial and antioxidant potential of Pongamia pinnata in Wistar rats. J Traditional Complement Med. 2016;7(1):79–85.
Mishra S, Kolla AP, Bajpai R, Pandey C, Kolla V. Formulation and evaluation of herbal toothpaste against biofilm producing Staphylococcus aureus. NewBioWorld. 2023;5(1):37-44.
Obadoni BO, Ochuko PO. Phytochemical studies and comparative efficacy of the crude extracts of some homeostatic plants in Edo and Delta States of Nigeria. Glob J Pure Appl Sci. 2001;86:203-8.
Sapan Christine V. Colorimetric protein assay techniques. Biotech Appl Biochem. 1999;29(2):99-108.
Elzagheid MI. Laboratory activities to introduce carbohydrates qualitative analysis to college students. World J Chem Educ. 2018;6(2):82-6.
Almas K. (2002). The antimicrobial effects of seven different types of Asian chewing sticks. Odonto-Stomatol Trop. 2002;25(99):11-4.
Sofrata A, Santangelo EM, Azeem M, Borg-Karlson AK, Gustafsson A, Pütsep K. Benzyl isothiocyanate, a major component from Salvadora persica sticks, inhibits growth and virulence of oral pathogens. Sci Rep. 2011;1(1):178.
Balto H, Al-Nazhan S, Al-Mutairi A, Al-Sulaiman A. Antibacterial activity of Salvadora persica extracts against oral pathogenic bacteria. Saudi Med J. 2016;37(9):1001-6.
Srinivasan R, Chandrasekar MJ, Nanjan MJ, Suresh B. Antioxidant activity of Pongamia pinnata leaves. Pharm Biol. 2015;43(8):623-9.
Ramesh N, Selvamani P, Ramesh T. Phytochemical analysis and antibacterial activity of Millettia pinnata leaves. Int J Pharm Sci Res. 2019;10(4):1910-6.
Anhwange BA, Ugye TJ, Nyiaatagher TD. Chemical composition of Musa sapientum (banana) peels. Electr J Environ Agricult Food Chem. 2009;8(6):437-42.
Akinmoladun AC, Obuotor EM, Farombi EO. Evaluation of antioxidant and free radical scavenging capacities of some Nigerian indigenous medicinal plants. J Med Food. 2010;13(3):608-14.
Sofrata A, Claesson R, Lingström P, Gustafsson A. Strong antibacterial effect of miswak against oral microorganisms associated with periodontitis and caries. J Periodont. 2010;79(8):1474-9.
Al-Bayaty F, Wahab FK. The effect of Salvadora persica extract (miswak) and chlorhexidine gluconate on plaque formation and antibacterial activity. BMC Oral Health. 2013;13(1):40.
Gogoi P, Kalita D, Deka DC. Antibacterial activity of Pongamia pinnata (karanj) seed and leaf extracts against pathogenic bacteria. International Journal of Pharmaceutical Sciences Review and Research, 2017;45(1):53-8.
Moghadam A, Aghajani N, Daryabari SH. Comparative evaluation of antimicrobial activity of herbal and conventional toothpastes: An in vitro study. J Int Soc Prevent Community Dentist. 2019;9(4):362-8.
Prabu GR, Gnanamani A, Sadulla S. Natural products for oral care: herbal alternatives to synthetic chemicals. J Ayurveda Integr Med. 2020;11(3):233-41.