Cost analysis of antimicrobial drugs using a common commercial drug manual: an insight into rational prescribing
DOI:
https://doi.org/10.18203/2319-2003.ijbcp20251838Keywords:
Anti-microbials, Cost ratio, Cost variationAbstract
Background: At present, there are a lot of drug industries that manufacture their own brand for a given drug molecule. A thorough knowledge of cost of different brands of the drug molecule is necessary for doctors so that they can prescribe the affordable drug brand to the patient. This can improve the compliance and therapy outcome. The aim is to analyse the cost variation of drug molecules available in market and their comparison with drugs available in Jan Ausadhi Kendra.
Methods: Cross sectional descriptive study, using current index of medical specialities (CIMS) 2023 drug manual, the relevant details of some commonly used anti-microbials were obtained. The cost ratio and the percentage cost variation of different drugs were calculated.
Results: The highest cost ratio was for tablet Fluconazole and least for tablet Atazanavir 300 mg. The maximum % cost variation was for tablet Fluconazole and least for Injection Caspofungin. Some of the costly drugs in Janaushadhi store were tablet Norfloxacin-Tinidazole, Moxifloxacin, Cefuroxime, Azithromycin and Piperacillin-Tazobactam injection respectively.
Conclusion: Since there is a wide price variation in different brands of a given same anti-microbial agent, the clinicians need to focus on the cheapest drug brands available in the drug market so that they can reduce the cost burden on patients and improve the patient compliance.
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References
Gupta RK, Reddy PS. A calm looks on cost analysis of different brands of anti-epileptic drugs. J MGIMS. 2011;16(1):64-9.
Piette JD, Beard A, Rosland AM, McHorney CA. Beliefs that influence cost-related medication non-adherence among the “haves” and “have nots” with chronic diseases. Patient Pref Adher. 2017;5:389. DOI: https://doi.org/10.2147/PPA.S23111
Roy V, Rana P. Prescribing generics: All in a name. The Ind J Med Res. 2018;147(5):442. DOI: https://doi.org/10.4103/ijmr.IJMR_1940_17
Kardas P, Bishai WR. Compliance in infective medicine. Adv Stud Med. 2022;6(7):652-58.
Pharmacoeconomics: Principles, Methods, and Applications. Dipiro JT, Lamber RL, Yee GC, Matzke GR, Wells BG, Posey LM. Pharmacotherapy: a Pathophysiologic Approach. 19. New York, NY: McGraw-Hill. 2011.
Kardas P, Bishai WR. Compliance in infective medicine. Adv Stud Med. 2020;6(7):652-58
Shrank WH, Hoang T, Ettner SL, Glassman PA, Nair K, DeLapp D, et al. The implications of choice: prescribing generic or preferred pharmaceuticals improves medication adherence for chronic conditions. Arch Intern Med. 2020;166(3):332-7. DOI: https://doi.org/10.1001/archinte.166.3.332
Akila L, Rani RJ. Cost analysis of different brands of antianginal drugs available in India. Int J Basic Clin Pharmacol. 2022;4:860-3. DOI: https://doi.org/10.18203/2319-2003.ijbcp20150856
Garnett WR. Antiepileptic drug treatment: outcomes and adherence. Pharmacotherapy. 2000;20:191-9. DOI: https://doi.org/10.1592/phco.20.12.191S.35250
Gagne JJ, Kesselheim AS, Choudhry NK, Polinski JM, Hutchins D, Matlin OS, et al. Comparative effectiveness of generic versus brand-name antiepileptic medications. Epilepsy Behav. 2015;52(7):14-8. DOI: https://doi.org/10.1016/j.yebeh.2015.08.014
Singal GL, Nanda A, Kotwani A. A comparative evaluation of price and quality of some branded versus branded-generic medicines of the same manufacturer in India. Indian J Pharmacol. 2011;43:131-6. DOI: https://doi.org/10.4103/0253-7613.77344