A retrospective analysis of the burden and treatment patterns of esophageal cancer over one year in a tertiary healthcare institution in the Western Himalayan region

Authors

  • Nidhi Mahlawat Department of Pharmacology, Dr. Rajendra Prasad Government Medical College, Tanda, Kangra, Himachal Pradesh, India
  • Nitin Patiyal Department of Pharmacology, Dr. Rajendra Prasad Government Medical College, Tanda, Kangra, Himachal Pradesh, India https://orcid.org/0000-0003-3598-9691
  • Poorva Vias Department of Radiation and Oncology, Dr. Rajendra Prasad Government Medical College, Tanda, Kangra, Himachal Pradesh, India
  • Atal Sood Department of Pharmacology, Dr. Rajendra Prasad Government Medical College, Tanda, Kangra, Himachal Pradesh, India
  • Suruchi Bhagra Department of Microbiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20251835

Keywords:

Dysphagia, Esophageal cancer, Palliative care, Radiation oncology

Abstract

Background: Esophageal cancer (EC) is a highly aggressive malignancy with a poor prognosis, particularly in advanced stages. By 2024, EC incidence is expected to increase by 63.5% over 2020. The objective of the study was to analyse the EC burden and treatment patterns in Dr. RPGMC, Kangra, Himachal Pradesh, Radiotherapy and Oncology Department, with a focus on palliative radiotherapy.

Methods: A retrospective analysis of 83 patients treated at our institute between 2023 and 2024 for esophageal cancer (7.9% of all new cases). Patients received treatment in two groups: palliative (n=34) and radical (n=49). Analysis was done on demographic, histopathological, cancer staging, and treatment modalities data. Self-expandable metallic stent (SEMS) implantation, palliative chemotherapy, or radiotherapy were all considered forms of palliative care. It was evaluated if palliative radiotherapy improved dysphagia.

Results: Almost 8% of all cancers were esophageal cancers. There were 30.1% women and 69.8% men, with an average age of 63.9±9.6 years. In 98% of cases, squamous cell carcinoma was found. Of the palliative patients, three had SEMS placement, nine had chemotherapy, and twenty-two had radiotherapy. Following radiotherapy, dysphagia improved in 63.6% of palliative cases, or 68% of cases. Alcohol consumption and smoking were prevalent among men (76%).

Conclusions: The study highlights the burden of EC and the importance of tailored treatment strategies. While radical treatment remains the preferred approach, palliative care plays a crucial role in symptom management for advanced cases (alleviating dysphagia, improving QOL).

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Published

2025-06-24

How to Cite

Mahlawat, N., Patiyal, N., Vias, P., Sood, A., & Bhagra, S. (2025). A retrospective analysis of the burden and treatment patterns of esophageal cancer over one year in a tertiary healthcare institution in the Western Himalayan region. International Journal of Basic & Clinical Pharmacology, 14(4), 513–518. https://doi.org/10.18203/2319-2003.ijbcp20251835

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Original Research Articles