Clinical insights and management strategies in Takotsubo cardiomyopathy: a comprehensive review

Akansha Arewar; Suraj Dhankikar; Smruti Besekar; Marvel Bhosle; Diptesh Besekar

doi:10.18203/2319-2003.ijbcp20251071

Authors

Akansha Arewar East State Tennessee University, TN, USA
Suraj Dhankikar East State Tennessee University, TN, USA
Smruti Besekar Department of Pharmacology, JNMC, Sawangi, Wardha, Maharashtra, India
Marvel Bhosle Division of Criminology and Forensic Science, Karunya Institute of Technology and Sciences, Coimbatore, Tamil Nadu, India
Diptesh Besekar MOIL Limited Nagpur, Maharashtra, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20251071

Keywords:

Takotsubo cardiomyopathy, Broken heart syndrome, Stress cardiomyopathy, Management strategies

Abstract

Takotsubo cardiomyopathy (TCM) is characterized by transient left ventricular dysfunction typically triggered by stressors, presents diagnostic challenges resembling acute coronary syndrome (ACS). This comprehensive review synthesizes diverse triggers (stress, illness, therapies), diagnostic complexities (variability in criteria, imaging modalities), and management strategies (supportive care, tailored medications). Despite favourable outcomes with reversible ventricular dysfunction, heightened risks in specific cohorts (e.g., malignancies, post-PCI) underscore the need for refined diagnostic criteria and optimized therapies. Prospective studies are essential to enhance understanding and management of TCM, aiming to improve clinical outcomes and patient care.

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