Utilization patterns of drugs used in the treatment of chronic obstructive pulmonary disease in a tertiary hospital
DOI:
https://doi.org/10.18203/2319-2003.ijbcp20243828Keywords:
COPD, Corticosteroids, Muscarinic receptor antagonists, Selective beta-2 receptor agonists, Utilization patternsAbstract
Background: Chronic obstructive pulmonary disease (COPD) is a disease where there is a limitation of airflow that comes in and out of the lungs due to some abnormalities of the lung`s airway. COPD affects 10% of the global population and is associated with significant morbidity and mortality. The treatment aims to control the symptoms and achieve a good quality of life. The aim of this study is to identify the utilization patterns of different drugs used in the treatment of COPD in Sultan Qaboos University Hospital (SQUH).
Methods: This was a retrospective study that included 170 patients who received treatment for COPD. Patients’ data and drugs’ data were collected through accessing the TrackCare system at SQUH.
Results: The results show that 139 (81.8%) of patients were prescribed with muscarinic receptor antagonists followed by 131 (77.1%) patients who were prescribed with beta 2 receptor agonists. Salbutamol and tiotropium were the most specific drugs prescribed for 103 (60.6%) and 102 (60.0%) patients respectively. 24.7% of the patients received only one drug. There is evidence of a significant association between muscarinic receptor antagonist usage and gender.
Conclusion: This study shows the utilization patterns of drugs that were used in the treatment of COPD in a tertiary hospital.
Metrics
References
Ko FW, Chan KP, Hui DS, Goddard JR, Shaw JG, Reid DW, Yang IA. Acute excarebation of COPD. Respirology. 2016;21:1152-65.
Fazleen A, Wilkinson T. Early COPD: current evidence for diagnosis and management. Ther Adv Respir Dis. 2020;14:17534.
Vogelmeier CF, Román-Rodríguez M, Singh D, Han MK, Rodríguez-Roisin R, Ferguson GT. Goals of COPD treatment. Focus on symptoms and excarebations. Respir Med. 2020;166:105938.
Bollmeier SG, Hartmann AP. Management of chronic obstructive pulmonary disease: A review focusing on exacerbations. Am J Health Syst Pharm. 2020;77:259-68.
Global initiative for chronic obstructive lung disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease, 2019 report. Available at: https://goldcopd.org. Accessed on 23 August 20924.
Gentry S, Gentry B. Chronic obstructive pulmonar disease: diagnosis and management. American Family Physician. 2017;95:433-41.
Mittal N, Mittal R, Singh I, Shafiq N, Malhorta S. Drug utilization study in a tertiary care center: Recommendations for improving hospital drug dispensing policies. Ind J Pharma Sci. 2014;76:308-14.
Kaur S, Rajagopalan S, Kaur N, Shafiq N, Bhalla A, Pandhi P, et al. Drug utilization study in medical emergency unit of a tertiary care hospital in north India. Emergency Med International. 2014;9:73578.
Jyothi D, Prasad SV, Vangoori Y, Bharatha A. (2020) A prospective study on prescription pattern in chronic obstructive pulmonary disease. Madica. 2020;15:37-44.
Sawant MP, Padwal SL, Kale AS, Pise HN, Shinde RM. Study of drug prescription pattern among COPD patients admitted to medicine in-patient department of tertiary care hospital. Int J Basic Clin Pharmacol. 2017;6:2228-32.
Kumar S, Madhuri G, Wilson A, George TS. Study of prescribing pattern of drugs in chronic obstructive pulmonary disease in tertiary care hospital. Indian J Family Practice. 2019;12:161-6.
Lisspers K, Larsson K, Janson C, Ställberg B, Tsiligianni I, Gutzwiller FS, et al. Gender differences among Swedish COPD patients: results from the ARCTIC, a real-world retrospective cohort study. NPJ Prim Care Respir Med. 2019;29(1):45.
Machado-Duque ME, Gaviria-Mendoza A, Valladales-Restrepo LF, González-Rangel A, Laucho-Contreras ME, Machado-Alba JE. Patterns and trends in the use of medications for COPD control in a cohort of 9476 Colombian patients, 2017-2019. Int J Chron Obstruct Pulmon Dis. 2023;18:1601-10.
Veettil SK, Rajiah K, Kumar S. Study of drug utilization pattern for acute exacerbation of chronic obstructive pulmonary disease in patients attending a government hospital in kerala, India. J Family Med Prim Care. 2014;3:250-4.
Miravitlles M, de la Roza C, Naberan K, Lamban M, Gobartt E, Martin A. Use of spirometry and patterns of prescribing in COPD in primary care. Respir Med. 2007;101(8):1753-60.