Bibliometric analysis on the publications of the statins-associated autoimmune myopathy: a comprehensive review

Smruti Besekar; Sangita Jogdand; Suraj Dhankikar; Akansha Arewar; Marvel Bhosle; Diptesh Besekar

doi:10.18203/2319-2003.ijbcp20243844

Authors

Smruti Besekar Department of Pharmacology, JNMC, Sawangi, Wardha, Maharashtra, India
Sangita Jogdand Department of Pharmacology, JNMC, Sawangi, Wardha, Maharashtra, India
Suraj Dhankikar Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, Tennessee, USA
Akansha Arewar Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, Tennessee, USA
Marvel Bhosle Karunya Institute of Technology, Coimbatore, Tamil Nadu, India
Diptesh Besekar Moil, Nagpur, Maharashtra, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20243844

Keywords:

Bibliometric analysis, Statin, Myopathy, SAAM, Hypolipidemic drug

Abstract

This bibliometric analysis aimed to assess the landscape of research on statin-associated autoimmune myopathy (SAAM), focusing on publication trends, contributors, and implications for further investigation. Access to the Scopus and Web of Science databases was obtained through institutional login credentials. An advanced search using keywords "statin associated autoimmune myopathy" or "SAAM" was conducted. Data were collected from 2003 to 2022 and analysed using the Biblioshiny package in R-Studio. A total of 110 publications were identified, involving 418 authors. The analysis revealed a steady increase in publication activity on SAAM, particularly notable in 2017, 2020, 2021, and 2022, with a peak of 13 publications in certain years. However, no publications were recorded in 2014. The accumulated citations from 2003 to 2022 totalled approximately 3,000, indicating a sustained interest in the topic. Statins, being first-line drugs for conditions like hyperlipidemia, diabetes mellitus, cardiovascular diseases, obesity, and cancer, underscore the importance of vigilant monitoring for associated adverse events. The analysis highlights the need for further research on SAAM, a drug-related adverse reaction, due to the widespread use of statins and their association with comorbidities. Understanding and monitoring SAAM is crucial for patient safety, and further investigation is needed to understand its mechanisms and risk factors.

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References

Nazir S, Lohani S, Tachamo N, Poudel D, Donato A. Statin-associated autoimmune myopathy: a systematic review of 100 cases. J Clin Rheumatol Pract Rep Rheum Musculoskelet Dis. 2017;23(3):149–54.

Patel PP, Jackson CD. When statins get physical: a curious cause of statin myopathy. South Med J. 2022;115(4):266–9.

Nazir S, Lohani S, Tachamo N, Poudel D, Donato A. Statin-associated autoimmune myopathy: a systematic review of 100 cases. J Clin Rheumatol Pract Rep Rheum Musculoskelet Dis. 2017;23(3):149–54.

Valor-Méndez L, Manger B, Knitza J, Schmidkonz C, Kleyer A, Schett G. Clinical images: tissue remodeling in autoimmune statin-induced necrotizing autoimmune myopathy. ACR Open Rheumatol. 2022;4(10):835–6.

Refractory statin-induced immune-mediated necrotizing myositis: challenges and perils in its management. Available at: www.researchgate.net. Accessed on 21 August 2024.

Escher AR, Hoffman JP, Alfieri S, Bordoni B, Evans RM. Immune-mediated myopathy in a patient presenting for melanoma resection and sentinel lymph node biopsy. Cureus. 2022;14(3):22777.

Shuster S, Awad S. A rare case of statin-induced necrotizing autoimmune myopathy. AACE Clin Case Rep. 2020;6(2):86–9.

Joudeh AI, Albuni MK, Hassen SS, Iqbal P, Aziz Bedair EM, Mahdi S. A case report of statin-induced immune-mediated necrotizing myopathy treatment challenges. Case Rep Rheumatol. 2022;2:4647227.

Barrons R. Statin-Associated Autoimmune Myopathy: Review of the Literature. J Pharm Pract. 2022;16:8971900211040291.

Mammen AL. Statin-associated myalgias and muscle injury-recognizing and managing both while still lowering the low-density lipoprotein. Med Clin North Am. 2021;105(2):263–72.

Somagutta MKR, Shama N, Pormento MKL, Jagani RP, Ngardig NN, Ghazarian K, et al. Statin-induced necrotizing autoimmune myopathy: a systematic review. Reumatologia. 2022;60(1):63–9.

Sharma A, Musurakis C, Nabil N, Poudel B, Trongtorsak A. A case series of statin-induced necrotizing autoimmune myopathy. Cureus. 2022;14(1):21613.

Wei J, Ketner E, Mammen AL. Increased risk of statin-associated autoimmune myopathy among American Indians. Arthritis Rheumatol Hoboken NJ. 2022;74(9):1602–3.

Jaffry H, Perdomo W, Cedano H, Khawaja U, Thomas A, Rudinskaya A. Statin induced necrotizing autoimmune myopathy without concurrent statin use: yet another sequela of covid-19? J Am Coll Cardiol. 2022;79(9):3337.

Potential implications of six American Indian patients with myopathy, statin exposure and anti-HMGCR antibodies. Rheumatol. Oxford Academic. Available at: https://academic.oup.com/rheumatology. Accessed on 12 August 2024.

Combined central retinal vein and cilioretinal artery occlusion in the setting of intravenous immunoglobulin administration - Jonathan Cin-Bon Tsui, Gordon Scott Crabtree. 2021. Available at: https://journals.sagepub.com. Accessed on 16 August 2024.

Webster P, Wiemer N, Al Harash A, Marshall C, Khatoon N, Lucke M. Challenges in Treating Statin-Associated Necrotizing Myopathy. Case Rep Rheumatol. 2021;2021:8810754.

Nemati M, Srai M, Rudrangi R. Statin-induced autoimmune myopathy. Cureus. 2021 Feb 26;13(2):13576.

Cha D, Wang F, Mukerji B, Mukerji V. Statin-induced necrotizing autoimmune myositis: diagnosis and management. Cureus. 2021;13(3):13787.

Safi T, Wagner H. Two cases of statin-induced immune-mediated necrotizing myopathy. Lakartidningen. 2021;118:21110.

Aijaz A, Lara FVD, Singh A, Ahuja S, Miyakawa L, Kim B. Statin-induced necrotizing autoimmune myopathy: a rare but serious cause of respiratory failure in the critically ill. Chest. 2021;160(4):728.

Sharma P, Timilsina B, Adhikari J, Parajuli P, Dhital R, Tachamo N. Statin-induced necrotizing autoimmune myopathy: an extremely rare adverse effect from statin use. J Community Hosp Intern Med Perspect. 2019;9(6):503–6.

Khan B, Newton L. E033 Statin-induced necrotizing autoimmune myopathy with anti HMG-CoA reductase antibodies. Rheumatol. 2019;58(3):kez110-32.

Saleh Y, Herzallah K, Hassanein M, Chang HT. Statin-induced necrotizing autoimmune myopathy: An uncommon complication of a commonly used medication. J Saudi Heart Assoc. 2019;31(4):269–72.

J DGD, Im CB. Proprotein convertase subtilisin/kexin type 9 antibody and statin-associated autoimmune myopathy. Ann Intern Med. 2019;171(1):237.

Pogosky AK, Dalal DS, DeNucci TD, Rupawala AH. Tu1548 – Statin-associated autoimmune myopathy: an unusual cause of persistent transaminasemia. Gastroenterology. 2019;156(6):34-8.

Dixit A, Abrudescu A. A case of atorvastatin-associated necrotizing autoimmune myopathy, mimicking idiopathic polymyositis. Case Rep Rheumatol. 2018;1:5931046.

Villa L, Lerario A, Calloni S, Peverelli L, Matinato C, DE Liso F, et al. Immune-mediated necrotizing myopathy due to statins exposure. Acta Myol Myopathies Cardiomyopathies Off J Mediterr Soc Myol. 2018;37(4):257–62.

Caughey GE, Gabb GM, Ronson S, Ward M, Beukelman T, Hill CL, et al. Association of statin exposure with histologically confirmed idiopathic inflammatory myositis in an Australian population. JAMA Intern Med. 2018;178(9):1224–30.

Selva-O’Callaghan A, Alvarado-Cardenas M, Pinal-Fernández I, Trallero-Araguás E, Milisenda JC, Martínez MÁ, et al. Statin-induced myalgia and myositis: an update on pathogenesis and clinical recommendations. Expert Rev Clin Immunol. 2018;14(3):215–24.

Khambhati J, Allard -Ratick Marc, Stahl E, Tahhan AS, Sandesara P. A severe case of statin-associated autoimmune myopathy. J Am Coll Cardiol. 2017;69(11):2240.

Sweidan AJ, Leung A, Kaiser CJ, Strube SJ, Dokukin AN, Romansky S, et al. A case of statin-associated autoimmune myopathy. Clinical Medicine Insights: Case Reports. 2017:23;10:1179.

Hussenbux A, Hofer M, Steuer A. Statin-induced necrotizing autoimmune myopathy: importance of early recognition. Br J Hosp Med Lond Engl 2005. 2017;78(6):352–3.

Tiniakou E, Christopher-Stine L. Immune-mediated necrotizing myopathy associated with statins: history and recent developments. Curr Opin Rheumatol. 2017;29(6):604–11.

Gilyarevskii RS. Publication activity as an indicator of scientific performance. Sci Tech Inf Process. 2014;41:170–7.

Open access vs. closed access | ZB MED – Informationszentrum Lebenswissenschaften. Available at: https://www.publisso.de/en/advice/ publishing-advice-faqs/open-access-vs-closed-access. Accessed on 25 February 2024.

Donthu N, Kumar S, Mukherjee D, Pandey N, Lim WM. How to conduct a bibliometric analysis: An overview and guidelines. J Bus Res. 2021;133:285–96.

Agnihotram DG. Standard statistical methods and calculation of sample size in Medical education research. Available at: https://www.pimr.org.in/ Gopinath-vol-6-issue-1-2018.PDF. Accessed on 17 March 2024.

What are Bibliometrics? - Bibliometrics - Research Guides at Embry-Riddle Aeronautical University. Available at: https://guides.erau.edu/bibliometrics. Accessed on 13 August 2024.

Bordons M, Zulueta MA. Evaluation of the scientific activity through bibliometric indices. Revista espanola de cardiologia. 1999;52(10):790-800.

Mammen AL. Statin-Associated Autoimmune Myopathy, N Engl J Med. 2016;374:664-9.

Manoj KL, George RJ. Bibliometric analysis for medical research. Indian J Psychol Med. 2023;45(3):277–82.