An expert consensus on managing allergic cough in the pediatric set-up

Authors

  • Sitesh Roy Dr. Roy Multi-Speciality Health Clinic, Bandra West, Mumbai, Maharashtra, India
  • Sridhar Ganapathy Ganapathy Clinic, Nanda Dham Co-operative Housing Society, Sion, Mumbai, Maharashtra, India
  • Ashish Mathur Dr. Ashish Singh's Child Care Clinic and Vaccination Centre, Lucknow, Uttar Pradesh, India
  • Ashok Chakarvarty Madhukar Children Hospital and Max Saket Hospital, New Delhi, Delhi, India
  • Devesh K. Joshi Department of Medical Affairs, Dr Reddy's Laboratories Ltd., Hyderabad, Telangana, India
  • Monil Gala Department of Medical Affairs, Dr Reddy's Laboratories Ltd., Hyderabad, Telangana, India
  • Snehal S. Muchhala Department of Medical Affairs, Dr Reddy's Laboratories Ltd., Hyderabad, Telangana, India
  • Bhavesh P. Kotak Department of Medical Affairs, Dr Reddy's Laboratories Ltd., Hyderabad, Telangana, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20242443

Keywords:

Allergic cough, Pediatric cough, Consensus statement

Abstract

Allergic cough frequently serves as a symptom of more comprehensive allergic conditions and is associated with a range of environmental and genetic factors. The presence of chronic conditions such as asthma, rhinitis, and sinusitis play a substantial role in the development of allergic cough in children. Allergic rhinitis affects up to 40% child population worldwide. Modified Delphi statements were prepared, and an agreement/disagreement was taken by12 expert paediatricians from India on these statements. The opinions of the expert panel were captured and documented. Consensus was predetermined to be obtained if more than 75% of the participants agreed (or remained neutral) on the statement. 12 pediatricians participated in the panel and provided opinions on 24 modified Delphi statements. All the statements were supported by the latest data from the literature search. 23 statements reached consensus after an agreement (agree + neutral) of more than 75%. In the event of non-agreement, 1 statement was amended as per the panel’s recommendation and sent for another round of deliberation. In the final phase, all the opinions from experts were consolidated and recommendations were framed. The present manuscript provides consensus recommendations for the pediatricians while addressing the allergic cough and related complications in the children. The key outline is to diagnose the proper cause of the cough and follow the proper treatment approach to avoid complications and have better management.

Metrics

Metrics Loading ...

References

Xiaochun L, Shuxian Q, Yiming S, Wuquan S. Analysis of risk factors of allergic cough in children. Arch Clin Psychiatry. 2023;50(6):262-9.

Palmer R, Anon JB, Gallagher P. Pediatric cough: what the otolaryngologist needs to know. Curr Opin Otolaryngol Head Neck Surg. 2011;19(3):204-9.

Ramanuja S, Kelkar PS. The approach to pediatric cough. Ann Allergy Asthma Immunol. 2010;105(1):3-8.

Holdings: Clinical Profile, Co-Morbidities and Health Related Quality of Life in Pediatric Patients with Allergic Rhinitis and Asthma. Available at: https://buscaintegrada.ufrj.br/Record/oai:doaj.org-article:747cbf053d244f7683a6351640a851a9. Accessed on 12 December 2023.

de Benedictis FM, Carloni I, Comberiati P, Shields MD, Bush A, Chang AB. Wet Cough and Nasal Symptoms in Children: Can We Do Better? Front Pediatr. 2019;7:489709.

Fan Y, Ji P, Leonard-Segal A, Sahajwalla CG. An overview of the pediatric medications for the symptomatic treatment of allergic rhinitis, cough, and cold. J Pharm Sci. 2013;102(12):4213-29.

2022 GINA Main Report. Global Initiative for Asthma - GINA. Available at: https://ginasthma.org/gina-reports/. Accessed on 12 December 2023.

Kumari V, Jagzape T. Bronchial asthma: Prevalence and risk factors among children in urban population from Raipur, Chhattisgarh. Indian J Allergy Asthma Immunol. 2019;33(1):45.

Remson MP, Krishnamoorthy S, Kandasamy S. Predictive prevalence of asthma in children with allergic rhinosinusitis. Int J Otorhinolaryngol Head Neck Surg. 2021;7(2):284.

Singh RK, Simalti AK. Coexistence of Allergic Rhinitis in Children Attending Paediatric Asthma Clinic. J Nepal Paediatr Soc. 2019;39(3):142-6.

Bavdekar S, Vora A, Karekar S. Pediatric cough as a symptom: Tips for management. Indian J Child Health. 2022;9(9).

Expert Panel Working Group of the National Heart, Lung, and Blood Institute (NHLBI) administered and coordinated National Asthma Education and Prevention Program Coordinating Committee (NAEPPCC); Cloutier MM, Baptist AP, Blake KV, Brooks EG, Bryant-Stephens T, DiMango E, et al. 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group. J Allergy Clin Immunol. 2020;146(6):1217-70.

Hamilos DL. Allergic fungal rhinitis and rhinosinusitis. Proceed Am Thoracic Soc. 2010;7(3):245-52.

Torres-Borrego J, Sánchez-Solís M. Dissecting Airborne Allergens. J Clin Med. 2023;12(18):5856.

Calderón MA, Linneberg A, Kleine-Tebbe J, De Blay F, Hernandez Fernandez de Rojas D, Virchow JC, et al. Respiratory allergy caused by house dust mites: What do we really know? J Allergy Clin Immunol. 2015;136(1):38-48.

Gupta N, Anand M. Allergy Skin Testing. J Pediatr Pulmonol. 2023;2(2):S112-8.

Satwani H, Rehman A, Ashraf S, Hassan A. Is serum total IgE levels a good predictor of allergies in children? J Pak Med Assoc. 2009;59(10):698-702.

Reddel HK, Bacharier LB, Bateman ED, Brightling CE, Brusselle GG, Buhl R, et al. Global Initiative for Asthma Strategy 2021: executive summary and rationale for key changes. Eur Respir J. 2021;59(1):2102730.

Ioan I, Poussel M, Coutier L, Plevkova J, Poliacek I, Bolser DC, et al. What is chronic cough in children? Front Physiol. 2014;5:322.

Niimi A. Cough and asthma. Curr Resp Med Rev. 2011;7(1):47-54.

Kim KH, Jahan SA, Kabir E. A review on human health perspective of air pollution with respect to allergies and asthma. Environ Int. 2013;59:41-52.

Matsunaga K, Kuwahira I, Hanaoka M, Saito J, Tsuburai T, Fukunaga K, et al; Japanese Respiratory Society Assembly on Pulmonary Physiology. An official JRS statement: The principles of fractional exhaled nitric oxide (FeNO) measurement and interpretation of the results in clinical practice. Respir Investig. 2021;59(1):34-52.

Small P, Keith PK, Kim H. Allergic rhinitis. Allergy Asthma Clin Immunol. 2018;14(Suppl 2):51.

Lam SHF, Homme J, Avarello J, Heins A, Pauze D, Mace S, et al. Use of antitussive medications in acute cough in young children. J Am Coll Emerg Physicians Open. 2021;2(3):e12467.

Thomas PK, Jog P, Vohra NR, Veligandla KC, Petare UA. A Newer Approach in the Management of Cough: A Review on Levodropropizine. J Resp Dis. 2023;1(3):1-14.

Aliprandi P, Castelli C, Bernorio S, Dell'Abate E, Carrara M. Levocloperastine in the treatment of chronic nonproductive cough: comparative efficacy versus standard antitussive agents. Drugs Exp Clin Res. 2004;30(4):133-41.

GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396(10258):1204-22.

2023 GINA Main Report. Global Initiative for Asthma - GINA. Available at: https://ginasthma.org/2023-gina-main-report/. Accessed on 12 May 2024.

Randall KL, Hawkins CA. Antihistamines and allergy. Australian Prescriber. 2018;41(2):41.

Twentyman OP, Oilier S, Holgate ST. The effect of H1-receptor blockade on the development of early-and late-phase bronchoconstriction and increased bronchial responsiveness in allergen-induced asthma. J Allergy Clin Immunol. 1993;91(6):1169-78.

Wasserfallen JB, Leuenberger P, Pécoud A. Effect of cetirizine, a new H1 antihistamine, on the early and late allergic reactions in a bronchial provocation test with allergen. J Allergy Clin Immunol. 1993;91(6):1189-97.

Zhou S, Huang G, Chen G. The antagonistic activity of H1 receptor antagonists as medicinal foods. Trends Food Sci Technol. 2020;105:1-16.

Barnes PJ. Inhaled corticosteroids. Pharmaceuticals. 2010;3(3):514-40.

Papi A, Blasi F, Canonica GW, Morandi L, Richeldi L, Rossi A. Treatment strategies for asthma: reshaping the concept of asthma management. Allergy Asthma Clin Immunol. 2020;16:75.

Chipps BE, Albers FC, Reilly L, Johnsson E, Cappelletti C, Papi A. Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study. BMJ Open Respir Res. 2021;8(1):e001077.

Chauhan BF, Ducharme FM. Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma. Cochrane Database Syst Rev. 2014;2014(1):CD003137.

Jain S, Verma S, Balamurugan S, Redd KRBK, Christopher DJ. Expert opinion on the role of bilastine and bilastine-montelukast combination in the management of allergic rhinitis: An Indian perspective. J Assoc Chest Phys. 2023;11(1):1.

Steiner NC, Lorentz A. Probiotic potential of Lactobacillus species in allergic rhinitis. Int Arch Allergy Immunol. 2021;182(9):807-18.

Downloads

Published

2024-08-28

How to Cite

Roy, S., Ganapathy, S., Mathur, A., Chakarvarty, A., Joshi, D. K., Gala, M., Muchhala, S. S., & Kotak, B. P. (2024). An expert consensus on managing allergic cough in the pediatric set-up. International Journal of Basic & Clinical Pharmacology, 13(5), 761–769. https://doi.org/10.18203/2319-2003.ijbcp20242443