Case report on anti-tuberculosis drug-induced hepatitis and pancreatitis

Authors

  • Karan Krishna Kurup Department of Clinical Pharmacist, Baby Memorial Hospital, Kannur, Kerala, India
  • Soorya N. Department of Medical Gastroenterologist, Baby Memorial Hospital, Kannur, Kerala, India
  • Atul Hareendran Department of Medical Gastroenterologist, Baby Memorial Hospital, Kannur, Kerala, India
  • Swathi Ajithan Department of Clinical Pharmacist, Baby Memorial Hospital, Kannur, Kerala, India
  • Sneha P. V. Department of Clinical Pharmacist, Baby Memorial Hospital, Kannur, Kerala, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20240387

Keywords:

TB, Drug-induced acute pancreatitis, Drug-induced hepatitis, Infectious disease

Abstract

Tuberculosis (TB) is a widespread infectious disease primarily impacting the lungs but with potential effects on various organs, such as bones, kidneys, and intestines. This case underscores a rare yet serious complication associated with anti-TB drug (ATD) treatment-the development of drug-induced acute pancreatitis. In this instance, a 65-year-old male undergoing ATD therapy exhibited symptoms including fever, vomiting, and fatigue. Despite receiving medical intervention, including intravenous antibiotics and hepatoprotective drugs, the patient's condition progressively worsened, ultimately resulting in a fatal outcome. This case emphasizes the crucial significance of early identification and effective management of such complications, highlighting the necessity for vigilant monitoring and regular assessment of liver function tests throughout ATD treatment.

References

Tuberculosis (TB) is a widespread infectious disease primarily impacting the lungs but with potential effects on various organs, such as bones, kidneys, and intestines. This case underscores a rare yet serious complication associated with anti-TB drug (ATD) treatment-the development of drug-induced acute pancreatitis. In this instance, a 65-year-old male undergoing ATD therapy exhibited symptoms including fever, vomiting, and fatigue. Despite receiving medical intervention, including intravenous antibiotics and hepatoprotective drugs, the patient's condition progressively worsened, ultimately resulting in a fatal outcome. This case emphasizes the crucial significance of early identification and effective management of such complications, highlighting the necessity for vigilant monitoring and regular assessment of liver function tests throughout ATD treatment.

Downloads

Published

2024-02-23

How to Cite

Kurup, K. K., N., S., Hareendran, A., Ajithan, S., & P. V., S. (2024). Case report on anti-tuberculosis drug-induced hepatitis and pancreatitis. International Journal of Basic & Clinical Pharmacology, 13(2), 280–282. https://doi.org/10.18203/2319-2003.ijbcp20240387

Issue

Section

Case Reports