Animal models of anxiety: a review

Authors

  • Ramyaa Desingu Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
  • Balakrishnan Sadasivam Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
  • Shamsher Singh Kalra Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
  • Bhawna Lakhawat Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20223368

Keywords:

Anxiety disorders, Anxiety models, Stress, Animal models

Abstract

Anxiety is a disorder that affects the quality of life and also imposes a huge economic burden. Animal models of anxiety have widened our understanding of the pathophysiology behind anxiety and to identify newer pharmacological compounds. Every behavioral test has its own limitations, and there are ways to minimize these like environment and handling. This review lists various experimental models of anxiety based on unlearned ethological models, learned responses like the Vogel conflict test, and psychological and physical stress models.

Author Biographies

Ramyaa Desingu, Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India

Department of Pharmacology

Balakrishnan Sadasivam, Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India

Department of Pharmacology

Shamsher Singh Kalra, Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India

Department of Pharmacology

Bhawna Lakhawat, Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India

Department of Pharmacology

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Published

2022-12-26

How to Cite

Desingu, R., Sadasivam, B., Kalra, S. S., & Lakhawat, B. (2022). Animal models of anxiety: a review. International Journal of Basic & Clinical Pharmacology, 12(1), 134–141. https://doi.org/10.18203/2319-2003.ijbcp20223368

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Section

Review Articles