An audit of drug utilization patterns, rationality, and cost analysis of antimicrobial medicines in a tertiary care teaching hospital in central suburban India

Suhrud Panchawagh; Ankita Pol; Uma Bhosale; Vasundhara Bhopale; Ayush Bhosale

doi:10.18203/2319-2003.ijbcp20223354

Authors

Suhrud Panchawagh Department of Pharmacology, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India http://orcid.org/0000-0002-8606-4202
Ankita Pol Department of Pharmacology, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
Uma Bhosale Department of Pharmacology, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
Vasundhara Bhopale Department of Pharmacology, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
Ayush Bhosale Department of Pharmacology, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20223354

Keywords:

Antimicrobial drugs, Drug utilization, Cost analysis, Rational drug use, Tertiary care teaching hospital

Abstract

Background: Antimicrobial medicine (AMM) utilization patterns and rational drug use are important topics in today’s world wrought with AMM resistance, irrational prescription of antibiotics, and lack of proper training such as stewardship programmes for medical graduates and general practitioners. Our objective was to perform an audit of the antimicrobial drug utilization pattern, evaluate the rationality of drug use, and perform a cost analysis of these drugs.

Methods: An observational cross-sectional study design was implemented. The study location was a tertiary care teaching hospital in suburban central India. Patients were recruited from the general medicine and general surgery departments.

Results: Out of 189 patients, the average age was 45.714 years and 67.725% were females. A total of 595 AMMs were prescribed to 189 patients with an average of 3.148±1.578 drugs per patient. 6.5% drugs prescribed were generic, 95% prescribed were included in the national essential medicine list, and 90% of patients’ prescriptions were rational. The total expenditure on AMMs was ₹726043.610, with a median expenditure of ₹987.320.

Conclusions: Drug utilization patterns vary between medicine and surgery departments. They also vary between different institutions within the same country. Creating a structured standardized training program to uniformly train healthcare professionals in conservative antibiotic prescription practices is needed. This study hopefully paves the way for future studies to target critical areas in AMM prescription and to prospectively assess the impact of a structured antibiotic stewardship program on AMM utilization patterns.

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