A study on the knowledge, attitude and practice of junior doctors to adverse drug event reporting in a tertiary care hospital, Manipur
DOI:
https://doi.org/10.18203/2319-2003.ijbcp20221830Keywords:
ADE, PvPI, Polypharmacy, OTC, HerbalAbstract
Background: The aim of the present study is to find out the ways to improve the status of adverse drug effect (ADE) reporting to the pharmacovigilance centres.
Methods: The present study is a cross-sectional study with purposive sampling. Descriptive statistics is used for analysing the data from the questionnaire using frequencies and percentages.
Results: The response on the questionnaire was 77.7%. The 90 participants knew the definition of ADE. The 91 participants want to report the ADEs of newly marketed drugs. Only 70 participants know about the existence of PvPI. The 80 participants did not consider all OTC drugs to be safe. 95 participants opined that all Herbal and non-allopathic drugs are not safe. The 69 participants replied that no ADE monitoring centre was available in SHIJA hospitals and research institute Pvt. Ltd. Though 90 participants knew the definition of ADE, only 85.1% of them considered to report it as a professional obligation. Maximum ADEs are seen with skin, paediatric and elderly patients as opined by 57.4% of the participants. Varied opinions of occurrence of ADEs according to the participants with polypharmacy was 70.3% and with foods and drinks was 40.6%. Although 85.1% participants have the attitude of reporting ADE, only 63.4% participants have good clarity when reporting and filling the ADE forms with careful observation of the risks and behaviour of the patients.
Conclusions: To promote ADE reporting, a regular awareness cum sensitization programme coupled with CME program is necessary at various levels of health-care providers.
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References
Brunton L, Knollman B, Hilal-Dandan R. Goodman and Gilman's, The pharmacological basis of therapeutics. 13th edn. McGraw-Hill Education/ Medical. 2018.
World Health Organization. Glossary of terms related to patient and medication safety: World Health Organization. 2005. Committee of Experts on Management Safety and Quality in Health Care (SP-SQS) Expert Group on Safe Medication Practices. 2005;13. Available at: http://www.bvs.org.ar/ pdf/seguridadpaciente.pdf. Accessed on 2 May 2022.
Lihite RJ, Lakhar M. An update on the pharmacovigilance programme of India. Front Pharmacol. 2015;6:194.
Kumar DA, Reddenna L, Basha SA. Pharmacovigilance program of India. Innovations in Pharmacy. 2015;6(1):189.
Kesharwani R, Singh D, Jacob V. Pharmacovigilance: present status and future prospects in India. Pharmatutor Pharmacy Infopedia. 2018.
Nimesh S, Chaudhary A, Sharma A. Pharmacovigilance program of India: a review. Acta Scientific Pharmaceutical Sci. 2019;3(9):12-7.
Desai CK, Iyer G, Panchal J. An evaluation of knowledge, attitude and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspectives Clin Res. 2011;2(4):129-36.
Dutta S, Sengupta S. An evaluation of knowledge, attitude and practice of adverse drug reaction reporting in a tertiary care teaching hospital of Sikkim. Perspect Clin Res. 2015;6(4):200-6.
Tandon VR, Mahajan V, Khajuria V. Under-reporting of adverse drug reactions: a challenge for pharmacovigilance in India. Indian J Pharmacol. 2015;47(1):65-71.
Mulchandani R, Kakkar AK. Reporting of adverse drug reactions in India: a review of the current scenario, obstacles and possible solutions. Int J Risk Safety Med. 2019;30(1):33-44.
Amale PN, Deshpande SA, Nakhate YD. Pharmacovigilance Process in India: an overview. J Pharmacovigilance. 2018;6(2):259.
Dhananjay K, Himasri E. A study of assessing knowledge, attitude and practice of pharmacovigilance among medical students of a south Indian teaching Hosptial. Int J Basic Clin Pharmacol. 2017;6(1):43-7.
Kalyani SSA, Shristha P. An epidemiological study on adverse drug reactions in Indian population: metaanalysis. Indian J Pharmaceutical Clin Res. 2017;9(10):654-9.
Khan SA, Goyal C, Chandel N. Knowledge, attitudes and practice of doctors to adverse drug reaction reporting in a teaching hospital in India: an observational study. J Natural Sci Biol Med. 2013;4(1):191-6.
Singh OJ, Valte V, Oinam J. To study the knowledge, attitude and practice of the pharmacovigilance among the second professional MBBS students of The JN Institute of Medical Sciences, Imphal. J Evolution of Med and Dental Sci. 2015;4(61):10619-23.
Biswas M, Singh KNM, Shetty YC. Prescription pattern and adverse drug reactions of prokinetics. Indian J Med Res. 2019;149(6):748-54.
Manohar NS, Valte V, Singh OJ. An observational study of the knowledge, attitude and practice of ADR reporting among the junior doctors of jawaharlal nehru institute of medical sciences (JNIMS), Imphal. J Evolution Med Dent Sci. 2020;9(24):1800-3.
Modi A, Desai M, Shah S. Analysis of cutaneous adverse drug reactions reported at the regional ADR monitoring centre. Indian J Dermatol. 2019;64(3):250.
Tekel MT, Bekalu AF, Sema FD. Knowledge, Attitude, and Practice of Medical, Pharmacy, and Nursing Students Towards Pharmacovigilance and Adverse Drug Reaction Reporting at University of Gondar College of Medicine and Health Sciences, Northwest Ethiopia: A Cross-Sectional Study. Adv Med Educ Pract. 2021;12:1129-39.
Kumari A, Haque I, Bhyan SJ, Sreelakshmi M, Goel N, Jain A et al. Knowledge, Attitude and Practice of Adverse Drug Reaction Monitoring and Pharmacovigilance among Various Healthcare Professionals in India. Preprints. 2020;2020080067.
Haines HM, Meyer JC, Summers RS. Knowledge, attitudes and practices of health care professionals towards adverse drug reaction reporting in public sector primary health care facilities in a South African district. Eur J Clin Pharmacol. 2020;76:991-1001.
Acharya R, Naik R, Rang S, Jani CA, Galib R. Knowledge, attitude and practice towards pharmacovigilance among Ayurveda physicians and teachers of Gujarat State: A cross sectional study. J Family Med Prim Care. 2022;11:623-32.
Gordhon Y, Padayachee N. Evaluating the knowledge, attitudes and practices of healthcare workers towards adverse drug reaction reporting at a public tertiary hospital in Johannesburg. Int J Africa Nursing Sci. 2020;12:100191.