Evaluate the prevalence of risk factors among patients of myocardial infarction in our population: review of one hundred forty-seven cases

Authors

  • Tirth Bhavsar Department of Pharmacology, Smt. NHLM Medical College, Ahmedabad, Gujarat, India
  • Devang Rana Department of Pharmacology, Smt. NHLM Medical College, Ahmedabad, Gujarat, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20222746

Keywords:

Myocardial infarction, CAD, STEMI, DM

Abstract

Background: CAD is disease of persons older than 45 years of age. In India, CAD in males, it manifests earlier than west European and North American males. This study is designed to study prevalence of risk factors (and angiographic profiles) amongst patients of Myocardial infarction in our population.

Methods: Total of 147 consecutive patients of AMI were studied for risk factors.

Results: Out of 147 patients, 116 (79%) were males and 31 (21%) were females. 11 (9.5%) of males and 01 (3.2%) of females were below 40 years of age. Whereas 34 (29.3%) of males and 06 (19.4%) females were of below 50 years of age. Median age for males was 54 years while that for females was 63 years. Smoking remains most prevalent amongst males while high LDL and HT remain most prevalent amongst young and overall females respectively. 108 patients had STEMI while 39 had NSTEMI.

Conclusions: AMI occurs much frequently in males. Median age for males is almost one decade earlier than West European males and nearly 5 years earlier than North American males. Smoking is most common and hypertension second most common risk factors amongst males. In females median age for AMI is almost one decade later than Indian males. It is similar to North American females while nearly 5 years earlier than Western Europe females. HT and DM remain first and second common risk factors amongst females.

 

Author Biographies

Tirth Bhavsar, Department of Pharmacology, Smt. NHLM Medical College, Ahmedabad, Gujarat, India

Medical Intern, Smt. NHLMMC AHmedabad

Devang Rana, Department of Pharmacology, Smt. NHLM Medical College, Ahmedabad, Gujarat, India

Pharmacology

References

Husain A. Lungs. In: Robbins and Cotran pathologic basis of disease. 10th ed. USA: Elsevier/Saunders; 2017:495-548.

Jameson JL, Fauci AS, Kasper Dl, Hauser SL, Longo D, Loscalzo J. Harrison’s principles of internal medicine. 20th ed. New York: McGraw Hill; 2018: 1850.

Naghavi M, Abajobir AA, Abbafati C. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1151-210.

Murray CJL, Lopez AD. The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries, and risk factors in 1990 and projected to 2020. Boston: Harvard School of Public Health; 1996.

Yusuf S, Reddy S, Ôunpuu S, Anand S. Global burden of cardiovascular diseases: general considerations, the epidemiologic transition, risk factors, and impact of urbanization. Circulation. 2001;104:2746-53.

Pais P, Pogue J, Gerstein H. Risk factors for acute myocardial infarction in Indians: a case-control study. Lancet. 1996;348:358-63.

Yusuf S, Reddy S, Ôunpuu S, Anand S. Global burden of cardiovascular diseases, part II: variations in cardiovascular disease by specific ethnic groups and geographic regions and prevention strategies. Circulation. 2001;104: 2855-64.

Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries: case-control study. Lancet. 2004;364:937-52.

Blood pressure lowering treatment trialists’ collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively designed overviews of randomized trials. Lancet. 2003;362:1527-35.

Heart protection study collaborative group. MRC/BHF heart protection study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet. 2003;361:2005-16.

de Lorgeril M, Salen P, Martin JL. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon diet heart study. Circulation. 1999;99:779-85.

Parish S, Collins R, Peto R. Cigarette smoking, tar yields, and non-fatal myocardial infarction: 14000 cases and 32000 controls in the United Kingdom. BMJ. 1995;311:471-7.

Doll R, Peto R, Boreham J, Sutherland I. Mortality in relation to smoking: 50 years’ observations on male British doctors. BMJ. 2004;328:1519-28.

Stamler J, Stamler R, Neaton JD. Low risk-factor profile long-term cardiovascular and noncardiovascular mortality and life expectancy: findings for 5 large cohorts of young adult and middle-aged men and women. JAMA. 1999;282: 2012-8.

Rosengren A, Dotevall A, Eriksson H, Wilhelmsen L. Optimal risk factors in the population: prognosis, prevalence, and secular trends. Eur Heart J. 2001; 22:136-44.

Neaton JD. Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention, Zoya Gurm and others, 2021. PLoS One. 2021;16(6):e0250801.

Medcalc Software Ltd, Ostend, Belgium. Available at: https://www.medcalc. org/download.php. Accessed on 20 October 2021.

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Published

2022-10-27

How to Cite

Bhavsar, T., & Rana, D. (2022). Evaluate the prevalence of risk factors among patients of myocardial infarction in our population: review of one hundred forty-seven cases. International Journal of Basic & Clinical Pharmacology, 11(6), 626–629. https://doi.org/10.18203/2319-2003.ijbcp20222746

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Section

Original Research Articles