DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20162432

Knowledge, attitude and practice of adverse drug reaction reporting among teaching and nonteaching hospital physicians

Vitthal B. Karande, Ramchandra B. Burute, Nitin N. Puram, Mangala B. Murthy, Shreyas B. Burute, Sunita J. Ramanand

Abstract


Background: Knowledge, attitude and practice (KAP) analysis may provide insight into the reasons associated with reporting of adverse drug reaction. Therefore study was carried out to investigate knowledge, attitude and practice of adverse drug reaction reporting and identify factors affecting reporting of adverse drug reactions among physicians in a teaching (THPs) and non-teaching hospital/s (NTHPs).

Methods: This was a questionnaire based cross sectional study. 6 items on knowledge, 3 on attitude and 1 on practice were scored and mean KAP score calculated. The score was graded as: 0-5 low, 6-8 moderate, 9-10 high. Factors influencing reporting of ADRs were studied. Chi square and student’s unpaired t test were used to study statistical significance intergroup.

Results: Out of 102, 61 were THPs and 41 NTHPs. KAP scores were similar in both groups. Both groups believed in reporting all ADRs to new and old drugs. Most did not know where to obtain a form/ if an ADR monitoring centre existed in town. Most were ready to report an ADR to ADR monitoring centre while very few had actually reported. Most were unaware how and where to report. THPs seemed more concerned about being considered negligent in duty and had difficulties identifying ADRs correctly.

Conclusions: Groups had moderate knowledge, attitude and practice (KAP) score but there is scope for improvement. Attitude to reporting is positive. Concerns regarding blame for negligence in duty, difficulty in identifying ADRs, how and where to report exist. There is a need to create awareness among physicians and address these factors.


Keywords


Adverse drug monitoring centre, Knowledge, Attitude, Practice, Physicians

Full Text:

PDF

References


Beard K. Adverse reactions as a cause of hospital admission in the aged. Drugs Aging. 1992;2:356-67.

Tripathi KD. Adverse drug effects. In Tripathi KD (Ed). Essentials of medical pharmacology, 7th edition. New Delhi, Jaypee Brothers Medical Publishers, 2013;82-91.

Ramesh M, Pandit J, Parthasarathi G. Adverse drug reactions in a south Indian hospital-their severity and cost involved. Pharmacoepidemiol Drug Saf. 2003;12:687-92.

Arulmani R, Rajendran SD, Suresh B. Adverse drug reaction monitoring in a secondary care hospital in South India. Br J Clin Pharmacol. 2008;65:210-6.

Desai CK, Iyer G, Panchal J, Shah S, Dikshit RK. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspect Clin Res. 2011;2:129-36.

Ahmad A, Parimalkrishnan S, Mohanta GP, Manna PK, Manavalan R. Incidence of adverse drug reactions with commonly prescribed drugs in tertiary care teaching hospital in India. Int J Phar Sci. 2011;3:79-83.

Eland IA, Belton KJ, van Groothest AC, Meiners AP, Rawlins MD, Stricker BH. Attitudinal survey of voluntary reporting of adverse drug reactions. Br J Clin Pharmacol.1999;48(4):623-7.

Rishi RK, Patel RK, Bhandari A. Under reporting of ADR by medical practitioners in India-results of pilot study. Adv Pharmacopidem Drug Safety. 2012;1:112.

Abubakar AR, Simback BN, Mainul H. A systemic review of knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among doctors. Journal of Applied Pharmaceutical Science. 2014;4(11):117-27.

Chopra D, Wardhan N, Rehan HS. Knowledge, attitude and practices associated with adverse drug reaction reporting among doctors in teaching hospital International journal of risk and safety in medicine. 2011;23(4):227-32.

Khan SA, Goyal C, Chandel N, Rafi M. Knowledge, attitudes and practice of doctors to adverse drug reaction reporting in a teaching hospital in India. Journal of natural science, biology and medicine. 2013;4(1):191-6.

Ekman E, Backstorm M. Attitudes among hospital physicians to the reporting of adverse drug reactions in Sweden. Eur J clin Pharmacol. 2009;65(1):43-6.

Pavelin MS, Bengea-Luculescu S, Toma M, Paveliu SF. Perception on adverse drug reaction reporting by physicians working in Southern Romania. Journal of Clinical Medicine. 2013;8(1):17-25.

Sanghavi DR, Dhande PP, Pandit VA. Perception of pharmaqcovigilance among doctors in tertiary care hospital: influence of an intreventional lecture. Int J Risk Saf Med. 2013;25(4):197-204.

Heard GC, Sanderson PM, Thomas RD. Barrier to adverse events and error reporting in anaesthesia. Anesth Analg. 2012;114(3):604-14.

Goyal M, Bansal M, Yadav S, Grover V, Preetkanwal. To assess the attitude, knowledge and practice of medical professional about adverse drug reaction and their reporting in teaching hospital. Indian journal of clinical practice. 2013;24(3):281-4.

Oshikoya KA, Awobusuyi JO. Perception of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria. BMC Clin Pharmacol. 2009;9:14.

Goldstein LH, Berlin M, Saliba W, Elias M, Berkovitch M. Founding an adverse drug reaction (ADR) network: a method for improving doctors spontaneous ADR reporting in a general hospital. J Clin Pharmacol. 2013;53:1220-5.

Dhikav V, Singh S, Anand KS. Adverse drug reaction monitoring in India. JIACM. 2004;5(1):27-33.

Selvan N, Saravanan R, Sakthibalan M. Effect of educationl interventions on pharmacovigilance awareness among M.B.B.S. internee’s in a tertiary care hospital. International journal of basic and clinical pharmacology. 2016;35(1):149-54.

Bhist M, Singh S, Dhasmana DC. Effect of educational interventions on adverse drug reporting by physicians: across sectional study. ISRN Pharmacology. 2014;2014:1-5.

Figueiras A, Herdeiro MT, Polónia J, Gestal-Otero JJ. An educational intervention to improve physician reporting of adverse drug reactions: a cluster-randomized controlled trial. JAMA. 2006;296:1086-93.

Tabali M, Jeschke E, Bockelbrink A, Witt CM, Willich SN, Ostermann T, et al. Educational intervention to improve physician reporting of adverse drug reactions (ADRs) in a primary care setting in complementary and alternative medicine. BMC Public Health. 2009;9:274.