A prospective study of prescribing pattern of drugs among in-patients of gynaecology department in a tertiary care teaching hospital in South India

Authors

  • Bhanu Prakash Kolasani Department of Pharmacology, Vinayaka Missions Medical College and Hospital, Kottuchery, Karaikal-609609, Puducherry, India
  • Prasanand Sasidharan Department of Pharmacology, Vinayaka Missions Medical College and Hospital, Kottuchery, Karaikal-609609, Puducherry, India
  • Divyashanthi CM Department of Pharmacology, Vinayaka Missions Medical College and Hospital, Kottuchery, Karaikal-609609, Puducherry, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20162429

Keywords:

Prescribing pattern, Antimicrobial agents, Generic name, Essential drug list

Abstract

Background: Analysis of prescribing pattern can be helpful for the assessing the beneficial and adverse impacts of the prescribed drugs. Even though drugs used for gynaecological disorders are one of the commonly used, they are least studied in terms of prescribing patterns. Hence the present study was planned to analyse the prescribing pattern of drugs among in-patients of gynaecology department in our institute.

Methods: A prospective observational study was carried out in a total of 162 in-patients of department of gynaecology in our institute for a period of one year. Along with baseline demographic data, the total number and categories of drugs prescribed, percentage of individual drugs in each category, their dosage forms, percentage of drugs prescribed by generic name and drugs prescribed from essential drug list were analysed.

Results: Overall a total of 1647 drugs were prescribed. Antimicrobial agents (35.76%), vitamin and mineral preparations (28.29%) and anti-ulcer drugs (10.32%) were the top three categories of drugs prescribed in our study. Metronidazole (27.34%) was the most commonly prescribed antimicrobial drug whereas ferrous sulphate (31.97%) was the highest prescribed vitamin and mineral preparation. Among the anti-ulcer drugs, ranitidine (89.42%) was the most frequently prescribed drug. Most commonly used analgesic was diclofenac (59.05%), antiemetic was ondansetron (77.92%) and intravenous fluid was ringer lactate (37.03%). Tablet was the most common dosage form (38.01%) followed closely by injection (33.27%). The percentage of drugs prescribed by generic name was 26.17% and from essential drug list was 84.86%.

Conclusions: Antimicrobial agents and vitamins and mineral preparations were the most commonly prescribed drugs. Usage of injections should be reduced as they were relatively more commonly prescribed in our study. Prescription of drugs by generic names must be increased substantially to reduce the economic burden on patients.

References

Pavani V, Manasa C, Nalini M, Ramya TK, Parmar YM. Study of prescribing pattern of common health problems. International Journal of Pharma and Bio Sciences. 2012;2(4):22-31.

Sharma AK, Dahiya N, Kairi JK, Bharati SM. Prescription patterns of antihypertensive drugs in a tertiary care hospital in India. Int J Basic Clin Pharmacol. 2015;4(1):55-9.

Dumoulin J, Kaddar M, Velásquez G. Access to drugs and finance: basic economic and financial analysis. Geneva, World Health Organization; 1991.

Tripathi KD. Aspects of pharmacotherapy; clinical pharmacology and drug development. In: Essentials of medical pharmacology. 6th edition. New Delhi: Jaypee Brothers; 2008:68-71.

Patel V, Vaidya R, Naik D, Borker P. Irrational drug use in India: a prescription survey from Goa. J Postgrad Med. 2005;51(1):9-12.

Mohanty BK, Aswini M, Hasamnis AA, Patil SS, Murty KSN, Jena SK. Prescription pattern in Rajahmundry, India. Journal of Clinical and Diagnostic Research. 2010;(4):2047-51.

Dutta A, Chakraborty S. Practice of rational drug uses in a rural area of 24 pgs(s) in West Bengal. J Adv Pharm Tech Res. 2010;1(3):356-64.

Gulhati CM. Marketing of medicines in India. BMJ. 2004;328:778.

Walraven G, Zuberi N, Temmerman M. The silent burden of gynecological disease in low income countries. BJOG, International journal of Obstetrics and gynecology. 2005;112:1177-9.

International institute for population sciences (IIPS) and macro international. National Family Health Survey (NFHS-3), Mumbai India: (I): IIPS; 2007.

Shankar PR, Partha P, Nagesh S. Prescribing patterns in medical outpatients. Int J Clin Pract. 2002;56:549-51.

Kanakambal S, Murugesh N, Shanthi M. Drug prescribing pattern in a tertiary care teaching hospital in Madurai. Ind J Pharmacol. 2001;33:223.

Laporte JR, Porta M, Capella D. Drug utilization studies: a tool for determining the effectiveness of drug use. Br J Clin Pharmacol. 1983;16:301-4.

Hogerzeil HV. Promoting rational prescribing: an international perspective. Br J Clin Pharmacol. 1995;39:1-6.

Kaur S, Talwar R, Sabharwal D, Raut DK. Knowledge about transmission dynamics of sexually transmitted infections. Indian medical Gazette. 2011:470-5.

Shalini S, Murthy NS, Shalini CN, Rajanna MS, Geethamani V. Study of reproductive tract infections among women attending Urban Health centres in Banglore city. Indian J Prev Soc Med. 2011;42(3):267-72.

Ravi R, Nair SB. Correlates of sexually transmitted infections among women in Southern India. The Journal of Family Welfare. 2011;57(1):45-54.

Thappa DM, Kaimal S. Sexually transmitted infections in India: current status (except human immunodeficiency virus/aquired immunodeficiency syndrome). Indian J Dermatol. 2007;52(2):78-82.

Shah BK, Shah VN. Antimicrobial use by department of obstetrics and gynecology of a tertiary care hospital: analysis for rationality and other aspects. J Obstet Gynecol Ind. 2004:54(4);387-92.

Shivong A, Phouthavane T, Lundborg CS, Sayabounthavong K, Syhakhang, Wahlstrom R. Reproductive tract infections among women attending a gynecology outpatient department in Vientiane, Lao PDR. Sexually Transmitted Diseases. 2007;34(10):791-5.

Patel SV, Baxi RK, Kotecha PV. A case control study of pelvic inflammatory disease (PID) and its association with IUD (intra uterine device). J Obstet Gynecol India. 2008;58(4):333-7.

Lofmark S, Edlund C, Nord CE. Metronidazole is still the drug of choice for treatment of anaerobic infections. Clinical Infectious Diseases. 2010;50:16-23.

Massele AY, Mwaluko GM. A study of prescribing patterns at different health care facilities in Dar es Salaam, Tanzania. East Afr Med J. 1994;71:314-6.

Ministry of Health and Family Welfare Government of India. National guidelines on prevention, management and control of reproductive tract infections including sexually transmitted infections; 2012.

Bhatia JC, Cleland J. Reported symptoms of gynecological morbidity and their treatment in south India. Stud Fam Plann. 1995;26:203-16.

MS B, TR B, SN G, Sonali D, SM D. Drug utilization study of gynecology opd: in a tertiary care hospital. IJMRHS. 2013;2(2):156-63.

Darji NH, Vaniya HV, Doshi CM, Hedamba RH, Jadav SP, Trivedi HR. Prescription audit in the inpatients of a tertiary care hospital attached with medical college. J Clin Exp Res. 2015;3(2):197-200.

Rehan HS, Lal P. Drug prescribing pattern of interns at a government healthcare centre in northern India. Trop Doct. 2002;32:4-7.

Massele AY, Mwaluko GM. A study of prescribing patterns at different health care facilities in Dar es Salaam, Tanzania. East Afr Med J. 1994;71:314-6.

Kar SS, Pradhan HS, Mohanta GP. Concept of essential medicines and rational use in public health. Indian J Community Med. 2010;35:10-3.

Downloads

Published

2017-01-05

How to Cite

Kolasani, B. P., Sasidharan, P., & CM, D. (2017). A prospective study of prescribing pattern of drugs among in-patients of gynaecology department in a tertiary care teaching hospital in South India. International Journal of Basic & Clinical Pharmacology, 5(4), 1321–1326. https://doi.org/10.18203/2319-2003.ijbcp20162429

Issue

Section

Original Research Articles