Published: 2021-05-25

Lasmiditan: the first neurally acting anti-migraine drug

Sangeeta Bhanwra, Sonia S. Mahajan, Rajiv Kumar


Lasmiditan is the first neurally acting drug for the treatment of acute migraine. It is a highly selective, orally acting 5-HT1F agonist that was approved in November 2019, for the acute treatment of migraine in adults, with or without aura, by USFDA. Lesmiditan may help in terminating the acute attack of migraine by inhibiting the central and peripheral neuronal activity and the release of CGRP.


Lasmiditan, 5-HT1F agonist, Migraine

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