Lithium carbonate toxicity in an elderly patient: a case report

Authors

  • Ankit Bhardwaj Department of Pharmacology, ABVIMS and RML Hospital, Delhi, India
  • Vandana Roy Department of Pharmacology, MAMC and LNJP, Hospital, Delhi, India
  • Manik S. Ghadlinge’s Department of Pharmacology, ABVIMS and RML Hospital, Delhi, India
  • Anubhav Dua Department of Psychiatry, SIMS, Hapur, Uttar Pradesh, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20212091

Keywords:

Lithium toxicity, Pharmacokinetics, Therapeutic drug monitoring, Hemodialysis

Abstract

A case report of a 73-year-old man admitted in the intensive care unit with acute renal failure and lithium toxicity is reported. Lithium is a gold standard drug for bipolar disorder. It has a narrow therapeutic index and requires blood level monitoring frequently. Hemodialysis is the last resort in management of lithium toxicity but in between high rebound levels during the dialysis result in persistent CNS toxicity.

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Author Biography

Ankit Bhardwaj, Department of Pharmacology, ABVIMS and RML Hospital, Delhi, India

Senior Resident 2nd-year

Dept of neuropsychopharmacology

Institue of human behavior and allied sciences, Shahdara. 

References

National institute for health and care excellence (NICE) (2014) bipolar disorder: assessment and management, NICE Guideline (CG185) Available at: https://www.nice.org.uk/guidance/cg185. Accessed on 20 February 2021.

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Oakley PW, Whyte IM, Carter GL. Lithium toxicity: an iatrogenic problem in susceptible individuals. Aust J Psychiatry. 2001;35:833-40.

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Published

2021-05-25

How to Cite

Bhardwaj, A., Roy, V., Ghadlinge’s, M. S., & Dua, A. (2021). Lithium carbonate toxicity in an elderly patient: a case report. International Journal of Basic & Clinical Pharmacology, 10(6), 766–768. https://doi.org/10.18203/2319-2003.ijbcp20212091

Issue

Section

Case Reports