A prospective study on prescribing pattern of drugs in geriatric patients in the department of medicine in a tertiary care center

Authors

  • Priya Mohan B. N. Department of Pharmacology, Al Azhar Medical College and Super Specialty Hospital, Thodupuzha, Kerala, India
  • Suma Jayaram Department of Pharmacology, St. John’s Medical College and Super Specialty Hospital, Bangalore, Karnataka, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20210559

Keywords:

Elderly, Beer’s criteria, Inappropriate prescribing in the elderly tool, Polypharmacy

Abstract

Background: India stands at 3rd position with large elderly population in the world. Elderly population has special problems related to health, social support, and economic security. Comorbidities in elderly people are frequent, which require use of multiple medications which increases the number of inappropriate medications    noncompliance, economic burden, adverse drug reactions (ADRs), and drug interactions. The overall incidence of ADR is two to three times higher due to physiological and pharmacological variations. Currently used screening tools for inappropriate prescription in old age are: Beers criteria and inappropriate prescribing in the elderly tool (IPET).

Methods: A prospective observational study of elderly patients of either sex admitted in the medicine ward, conducted from May 2019-November 2019. A total of 102 prescriptions were collected and analysed. Data was analysed using Microsoft excel.

Results: In this study most of the patients (67 out of 102) were in the age group 65-70 years with male population (73%) dominance. Most of the patient were admitted due to cardiovascular (35.84%) and respiratory system (14.15%) disorder. Anti-diabetics (17.64%) followed by anti-microbials (14.24%) were the most commonly prescribed medicines in this study. Our study revealed poly pharmacy in geriatric patients with an average number of drugs per prescription being 6.07. According to BEER’s criteria 3.47% of total drugs prescribed were inappropriate

Conclusions:  In this study most of the patients had co morbid conditions, cardiovascular disease and diabetes being the common cause led to polypharmacy. A high number of potential prescription errors were found. 

Author Biography

Priya Mohan B. N., Department of Pharmacology, Al Azhar Medical College and Super Specialty Hospital, Thodupuzha, Kerala, India

ASSISTANT PROFESSOR, DEPARTMENT OF PHARMACOLOGY

References

Chanana HB, Talwar PP. Aging in India: Its Socio-economic and health implications. Asia Pac Popul J. 1987;2:23-38.

Zaveri HG, Mansuri SM, Patel VJ. Use of potentially inappropriate medicine in elderly: A prospective study in medicine outpatient department of a tertiary care teaching hospital. Indian J Pharmacol. 2010;42:95-8.

Klotz U. Pharmacokinetics and drug metabolism in the elderly. Drug Metab Rev. 2009;41:67-76.

Corsonello A, Pedone C, Incalzi RA. Age-related pharmacokinetic and pharmacodynamic changes and related risk of adverse drug reactions. Curr Med Chem. 2010;17:571-84.

Gorzoni ML, Fabbri RM, Pires SL. Potentially inappropriate medications in elderly. Rev Assoc Med Bras. 2012;58:442-6.

Helldén A, Bergman U, Von Euler M, Hentschke M, Odar-Cederlöf I, Ohlén G. Adverse drug reactions and impaired renal function in elderly patients admitted to the emergency department: A retrospective study. Drugs Aging. 2009;26:595-606.

Lund BC, Steinman MA, Chrischilles EA, Kaboli PJ. Beers Criteria as a proxy for inappropriate prescribing of other medications among older adults. Ann Pharmacother. 2011;45:1363-70.

Rozenfeld S, Fonseca MJM, Acurcio FA. Drug utilization and polypharmacy among the elderly: a survey in Rio de Janeiro City, Brazil. Rev Panam Salud Publica. 2008;23(1):34-43.

Zhan C, Sangl J, Bierman AS, Miller MR, Friedman B, Wickizer SW et al.Potentially inappropriate medication use in the community-dwelling elderly findings from the 1996 medical expenditure panel survey. JAMA. 2001;286:2823-9.

Lohani SP, Thapa P, Aryal UR, Satyal KR, Polypharmacy and geriatric patients: patterns of prescribing in the Thribuvan University Teaching Hospital in Nepal. J Nepal Health Res Council. 2006;4:1-4.

Shah RB, Gajjar BM, Desai SV. Drug utilization pattern among geriatric patients assessed with the anatomical therapeutic chemical classification/defined daily dose system in a rural tertiary care teaching hospital. Int J Neur Pharmacol Neurol Dis. 2012;2:258-65.

Shankar PR, Upadhyay DK, Subish P, Bhandari RB, Das B. Drug utilization among older inpatients in a teaching hospital in Western Nepal. Singapore Med J. 2010;51:28-34.

Harugeri A, Joseph J, Parthasarathi G, Ramesh M, Guido S. Potentially inappropriate medication uses in elderly patients: A study of prevalence and predictors in two teaching hospitals. J Postgrad Med. 2010;56:186-91.

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Published

2021-02-22

How to Cite

B. N., P. M., & Jayaram, S. (2021). A prospective study on prescribing pattern of drugs in geriatric patients in the department of medicine in a tertiary care center. International Journal of Basic & Clinical Pharmacology, 10(3), 293–296. https://doi.org/10.18203/2319-2003.ijbcp20210559

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Original Research Articles