Drug utilization study in patients visiting psychiatric OPD in tertiary care hospital


  • Ujwala P. Gawali Department of Pharmacology, Dr. VMGMC, Solapur, Maharashtra, India
  • Prashant S. Mishra Department of Pharmacology, Dr. VMGMC, Solapur, Maharashtra, India
  • salman H. Rizvi Department of Pharmacology, Dr. VMGMC, Solapur, Maharashtra, India
  • Sukhmeen Kaur Department of Pharmacology, MGM Medical College, Aurangabad, Maharashtra, India




Prescription, Psychiatry, Polypharmacy, Medication error, Psychotropic drugs


Background: The illness due to psychiatric diseases and behavioral disorders is enormous, but it remains under represented by conventional public health statistics; which mainly targets mortality more than morbidity or dysfunction. The drug utilization study was conducted to find out problems and provide feedback to prescribers so as to create awareness about irrational use of drugs. This study was conducted in psychiatry outpatient department (OPD) of a tertiary care hospital.

Methods: A prospective, observational and cross-sectional study was conducted in Department of Pharmacology in collaboration with department of psychiatry in a tertiary care hospital. Patients fulfilling the inclusion criteria visiting psychiatric OPD from 01 October 2018 to 31 December 2018 period of 3 months were enrolled in the study. Assessment of the prescriptions was done as per the ICD-10 criteria and World Health Organization-indicators for rational use of drugs (WHO-INRUD).

Results: Among total 390 prescriptions; 71.54% was males and 28.46% were females. All the drugs were oral formulations. The burden of diseases are depression 35.89%, anxiety 20.51%, schizophrenia 18.97% and bipolar disorder 11.28% and other psychiatric diseases were 13.33%. Olanzapine was the most common drug which was prescribed followed by alprazolam. Total 1,140 drugs were prescribed out of which 86.32% was psychotropic drug and 13.68% were other like vitamin B-complex, analgesics, anta-acids, antibiotics and NSAIDS. The Most common prescribed class was atypical antipsychotics 26.31% followed by benzodiazepines 20.26%, antipsychotics 19.74%, tricyclic antidepressants 8.16%, anticonvulsants 9.21%, antiepileptics 2.37% and lastly selective serotonin reuptake inhibitors.

Conclusions: Atypical antipsychotics was most commonly prescribed drug followed by benzodiazepines. All the drugs were prescribed by their generic names which suggests awareness among prescribers regarding WHO policies for generic prescribing.


WHO. Guide to Good Prescribing- A practical manual. Available at: https://apps.who.int/iris/bitstream/handle/10665/59001/WHO_DAP_94.11.pdf. Accessed on: 08 January 2021.

Sabu L, Yacob M, Singh H. Drug utilization pattern of psychotropic drugs in psychiatric outpatient department in a tertiary care teaching hospital. Asian J Pharm Clin Res. 2017;259-61.

Deshmukh DSA, Ismail DTSES. Evaluation Of Psychotropic Drugs Use Pattern Among Out Patients Attending Psychiatry Department At Government Medical College And Hospital, Nagpur: A Cross Sectional Study. Int J Pharm Bio Sci. 2012;3(3).

Drug Utilization Research: Methods and Applications. Available at: https://www.wiley.com/en-ae/Drug+Utilization+Research%3A+Methods+and+Applications-p-9781118949740. Accessed on: 19 December 2020.

Monégat M. Polypharmacy: definitions, measurement and stakes involved. Review of the literature and measurement tests. 2014;8.

Abdulraheem IS. Polypharmacy: A Risk Factor for Geriatric Syndrome, Morbidity & Mortality. Aging Sci. 2013;1(2).

Salman S, Ismail M, Awan NR, Anees M. Patterns of prescription writing in psychiatric clinics. J Postgrad Med Inst. 2013;27:290-6.

World Health Organization. Introduction to drug utilization research. 2003. Available at: https://apps.who.int/iris/handle/10665/42627. Accessed on: 19 December 2020.

Pharmacoepidemiology, 6th Edition. Available at: https://www.wiley.com/en-us/Pharmacoepidemiology%2C+6th+Edition-p-9781119413417. Accessed on: 08 January 2021.

Bapna JS. Drug utilization at primary health care level in southern India. Eur J Clin Pharmacol. 1992;43(4):413-5.

Sarkar P, Chakraborty K, Misra A, Shukla R, Swain SP. Pattern of psychotropic prescription in a tertiary care center: a critical analysis. Indian J Pharmacol. 2013;45(3):270-3.

Grover S, Avasthi A, Sinha V, Lakdawala B, Bathla M, Sethi S, et al. Indian Psychiatric Society multicentric study: Prescription patterns of psychotropics in India. Indian J Psychiatr. 2014;56(3):253.

Shamkuwar CA, Chakravorty AD, Shrivastava MP, Deshmukh R. Pattern of prescription and drug use in psychiatry out patient department of private practitioners of Central India. Int J Basic Clin Pharmacol. 2017;2(6):777-82.

Mental health of older adults. Available at: https://www.who.int/news-room/fact-sheets/detail/mental-health-of-older-adults. Accessed on: 08 January 2021.

Arvind BA, Gururaj G, Loganathan S NMHS collaborators group, et al. Prevalence and socioeconomic impact of depressive disorders in India: multisite population-based cross-sectional study. BMJ Open. 2019;9:e027250.

Mukherjee S. Prescribing Pattern of Psychotropic Medications in Psychiatry Outpatients at a Tertiary Care Teaching Hospital in India: A Prospective Cross-sectional Study. Int J Hospital Res.2014.

Nazroo JY, Edwards AC, Brown GW. Gender Differences in the Prevalence of Depression: Artefact, Alternative Disorders, Biology or Roles? Sociol Health Illness. 1998;20(3):312-30.




How to Cite

Gawali, U. P., Mishra, P. S., Rizvi, salman H., & Kaur, S. (2021). Drug utilization study in patients visiting psychiatric OPD in tertiary care hospital. International Journal of Basic & Clinical Pharmacology, 10(4), 342–346. https://doi.org/10.18203/2319-2003.ijbcp20211012



Original Research Articles