Drug utilization study in geriatric patients visiting medicine OPD in tertiary care hospital


  • Ujwala P. Gawali Department of Pharmacology, Dr Vaishampayan Memorial Government Medical College, Solapur, Maharashtra, India
  • Salman H. Rizvi Department of Pharmacology, Dr Vaishampayan Memorial Government Medical College, Solapur, Maharashtra, India http://orcid.org/0000-0002-4954-8080
  • Prashant S. Mishra Department of Pharmacology, Dr Vaishampayan Memorial Government Medical College, Solapur, Maharashtra, India




CVS, GI system, Medicine, Drug utilization study, Geriatric


Background: Drug utilization study is of utmost importance in the elderly. The consumption of drug amongst elderly segment of society is maximum and many of them use at least three prescribed drugs, concurrently. One of the plausible explanation of usage of large number of medicines is prevalence of multi-morbidities as well as suffer from chronic and degenerative pathology amongst them along with the alteration of pharmacokinetics and pharmacodynamics of many drugs are altered with advanced age. Thus, the aim of this study was to assess current prescribing practices among physicians for geriatric patients in tertiary care hospital.

Methods: A prospective, observational and cross-sectional study was conducted in Department of Pharmacology in collaboration with Department of Medicine in a tertiary healthcare hospital. As per inclusion criteria, patients visiting Medicine outpatient department (OPD) from 01 October 2018 to 31 December 2018 were enrolled in the study.

Results: The average number of drugs per encounter was 4.1. 100% of the drugs were prescribed by their generic name and those prescribed from World Health Organization (WHO) list of essential medicines were 70.2%. Analysis of polypharmacy showed maximum 11 and minimum 1 drug was prescribed. Overall analysis of the drugs showed, the most common route of administration was orally. Drugs acting on cardiovascular system (CVS), gastrointestinal system (GI) system, analgesics and anti-inflammatory drugs and vitamins and mineral supplements constitute the major bulk of drug prescribed.

Conclusions: In our study, though polypharmacy was found but it was necessary unavoidable, but was within the WHO standards of 1.6 to 4.8. Drugs acting on CVS and GI system were the most common drugs prescribed. Prescriptions with injections and steroids were less in the study population. All the drugs were prescribed by their generic name and most were present in the essential list of medicines.


Shalini S, Ravichandran V, Mohanty BK. Drug utilization studies – an overview. Intern J Pharma Sci Nanotech. 2010;3(1):803-10.

Gama H. Drug utilization studies. Arquivos De Medicina. 2008;22;(2):69-74.

Guaraldo L, Cano FG, Damasceno GS. Inappropriate medication use among the elderly: a systematic review of administrative databases. Biomed Central Geriatr. 2011;11:79.

Kaufman DW, Kelly JP, Rosenberg L, Anderson TE, Mitchell AA. Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. JAMA. 2002;287(3):337-44.

Barat I, Andreasen F, Damsgaard EMS: The consumption of drugs by 75-year-old individuals living in their own homes. Eur J Clin Pharmacol. 2000;56(6-7):5019.

Straand J, Rokstad K. Elderly patients in general practice: diagnoses, drugs and inappropriate prescriptions. A report from the Møre and Romsdal Prescription Study. Family Practice. 1999;16:380-8.

Bugeja G, Kumar A, Banerjee Arup K. Exclusion of elderly people from clinical research: a descriptive study of published reports. Br Med J. 1997;315:1059.

Zaveri HG, Mansuri SM, Patel VJ. Use of potentially inappropriate medicines in elderly: A prospective study in medicine out-patient department of a tertiary care teaching hospital. Indian J Pharmacol. 2010;42(2):95-8.

Fadare JO, Agboola SM, Opeke OA. Prescription pattern and prevalence of potentially inappropriate medications among elderly patients in a Nigerian rural tertiary hospital. Ther Clin Risk Manag. 2013;6:115-20.

Lenjisa JL, Fereja TH. A Retrospective Analysis of Prescribing Practice Based on WHO Prescribing Indicators at Four Selected Hospitals of West Ethiopia: Policy Implication. East Central Afr J Pharm Sci. 2013;16:69-74.

The Rational use of drugs, report on the conference of experts Nairobi sponsored by WHO Geneva. 1985. Available at: https://apps.who.int/iris/handle/10665/37174. Accessed on 02 December 2020.

Alam K, Mishra P, Prabhu M, Shankar PR, Plalain S, Bhandari RB, et al. A study on rational drug prescribing and dispensing in outpatients in a tertiary care teaching hospital of western Nepal. Kathmandu University Med J. 2006;4(4):436-43.

Good CB. Polypharmacy in elderly patients with diabetes. Diabetes Spectrum. 2002;15(4):240-8.

Salman S, Ismail M, Awan NR, Anees M. Patterns of prescription writing in psychiatric clinics. J Postgrad Med Inst. 2013;27(3):290-6.

World Health Organization. Fact sheet: WHO core drug use indicators. 2017. Available at http://apps.who.int/medicinedocs/en/d/Js2289e/3.html. Accessed on: 22 March 2019.

WHO Model Lists of Essential Medicines. 2019. Available at: https://www.who.int/medicines/publications/essentialmedicines/en/. Accessed on: 22 March 2019.

Nishandar TB, Kale AS, Pise HN. Drug Utilization Pattern In Geriatric Patients Attending Out Patient Department At Rural Tertiary Care Hospital In Maharashtra. Asian J Pharm Clin Res. 2017;10(2):314-6.

Jadhav RR, Jadhav AD, Padwal SL, Kale AS, Pise HN. Drug utilization pattern in geriatric out patient in tertiary care hospital. Int J Basic Clin Pharmacol. 2017;6:2078-81.

Goudanavar P, Keerthi Y, John SE, Jacob J, Krishna MSR. A Prospective Study on Medication Prescribing Pattern for Geriatric Patients in A Tertiary Care Teaching Hospital. Asian J Biomed Pharm Sci. 2016;6(56):23-7.




How to Cite

Gawali, U. P., Rizvi, S. H., & Mishra, P. S. (2021). Drug utilization study in geriatric patients visiting medicine OPD in tertiary care hospital. International Journal of Basic & Clinical Pharmacology, 10(4), 386–390. https://doi.org/10.18203/2319-2003.ijbcp20211020



Original Research Articles