DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20210191

Risperidone induced tardive dyskinesia

Elakkya Kolanchinathan, Dhanya Thirookaran Harichandran, Sujatha Mangattuvalappil Balakrishnan

Abstract


Risperidone is an atypical antipsychotic drug which has been less likely to produce extrapyramidal symptoms. The aim of this case report is to illustrate that low dose risperidone may cause tardive dyskinesia. A 29 year old male patient with 9 year history of paranoid schizophrenia, developed tardive dyskinesia after receiving risperidone 2 mg for 7 years. He had received small dosages of Haloperidol before the therapy of risperidone for short periods.


Keywords


Risperidone, Atypical antipsychotic, Tardive dyskinesia

Full Text:

PDF

References


Ayd FJ, Pies RW. A specific comparison of the atypical antipsychotics. Adv Psychopharmacol. 1997;61-2.

Brecher M. Long term safety ofrisperidone. Eur Neuropsychopharmacol. 1996;6(Suppl.3):170.

Van Kammen DP, Marder SR. Dopamine receptor antagonists In: Kaplan HI, Saddock B, eds. Comprehensive textbook of psychiatry. Baltimore: Williams and Wilkins; 1995:1987-2022.

Song F. Risperidone in the treatment of schizophrenia: a meta-analysis of randomized controlled trials. J Psychopharmacol. 1997;11:65-71.

Owens DG. Extrapyramidal side effects and tolerability of risperidone: a review. J Clin Psychiatry. 1994;55(suppl):29-35.

Woerner MG, Correll CU, Alvir JM, Greenwald B, Delman H, Kane JM. Incidence of Tardive dyskinesia with risperidone or olanzapine in elderly. 2011;36(8):1738-46.

Cornett EM, Novitch M, Kaye AD, Kata V, Kaye AM. Medication induced Tardive dyskinesia. Ochsner J. 2017;162-74.

Kumar S, Malone DM. Risperidone implicated in the onset of tardive dyskinesia in a young woman. Postgrad Med J. 2000;76(895):316-7.

Van Os J, Fahy T, Jones P, Harvey I, Toone B, Murray R. Tardive dyskinesia: who is at risk? Acta Psychiatr Scand. 1997 Sep;96(3):206-16.

Jeste DV, Lacro JP, Bailey A, Rockwell E, Harris MJ, Caligiuri MP. Lower incidence of tardive dyskinesia with risperidone compared with haloperidol in older patients. J Am Geriatr Soc. 1999;47(6):716-9.

Shireen E. Experimental treatment of antipsychotic-induced movement disorders. J Exp Pharmacol. 2016;8:1-10.