Acute psychosis induced by topiramate


  • Rajnish Raj Department of Psychiatry,Government Medical College and Rajindra Hospital,Patiala - 147 001, Punjab,India
  • Raj Kumar Department of Pharmacology, Guru Gobind Singh Medical College and Hospital, Baba Farid University of Health Sciences,Faridkot - 151 203,Punjab,India


Topiramate, Mania Rating Scale, Brief Psychiatric Rating Scale, Drug–drug interaction, CYP450


Topiramate (TPM) is a new potent antiepileptic drug (AED) used as add-on therapy for generalized and partial seizures that are resistant to the other AEDs; or as a mood stabilizer, and for reducing weight gain associated with olanzapine and clozapine in patients with bipolar disorder or schizophrenia. However, there is a higher risk of psychosis with TPM in patients with a past history of psychiatric disorder. This case report highlights emergence of psychosis that was related to TPM which resolved on discontinuation.


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How to Cite

Raj, R., & Kumar, R. (2017). Acute psychosis induced by topiramate. International Journal of Basic & Clinical Pharmacology, 3(2), 405–407. Retrieved from



Case Reports