DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20205135

Role of adjunctive vitamin C supplement therapy in combating COVID-19

Gnaneswari Regati Venkata

Abstract


Since the COVID-19 pandemic began in December 2019, the disease has continued to spread, highlighting the urgent need for immunization and a cure. People are seeking ways in which to potentially protect themselves from the virus or to alleviate its effects once caught.  This article reviews what vitamin C is, how it affects immunity, how it’s being tried for COVID-19 patients in a hospital setting. Vitamin C affects immune health in several ways through its antioxidant ability, collagen synthesis or directly strengthening cells in the fight against infection.


Keywords


COVID-19, Vitamin C, Immunity, Antioxidant, Infection

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References


Baladia E. Vitamin C for the Treatment of COVID-19. A Living Systematic Review. Epistemonicos Foundation. Medwave J. 2020.

Harapan H, Ttoh N, Yifika A, Winardi W, Keam S, Te H et al. Corona Virus Disease 2019 (A Literature Review). J Infect Public Health. 2020;13:667-673.

Kalpana P. Quiescence’s Pattern in Coronavirus Along with New Concern Of Recurrence, Relapse And Re-Infection Of SARS-Cov-2. Int J Basic Clin Pharmacol. 2020;9(8):1310-13.

Wiersinga WJ, Rhodes A, Cheng AC, Peacock SJ, Prescott HC. Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19) A Review. J Am med association. 2020;324(8):782-93.

Jain N, Choudhury A, Sharma J, Kumar V, De Divyendu, Tiwar R. A Review of Novel Coronavirus Infection (Coronavirus Disease-19). Global J Trans Med. 2020(5):1.

Mason RJ. Pathogenesis of COVID-19 from a cell biology perspective. Eur Respir J. 2020;55.

Liise-anne P, Casadevallb A. S Pathogenesis of COVID-19 from the Perspective of the Damage-Response Framework. Am Society Microbiol. 2020;11(4):e01175-20.

Dhont S, Derom E, Braecke EV, Depuydt P, Bart N. Lambrecht. The Pathophysiology of ‘Happy’ Hypoxemia In COVID-19. Respiratory Res. 2020;21:198.

Pal R. COVID-19, Hypothalamus-Pituitary-Adrenal Axis and Clinical Implications. Springer Nature. 2020;68(2):251-2.

Nikhra V. Exploring Pathophysiology of COVID-19 Infection: Faux Espoir and Dormant Therapeutic Options. Int J Clin Virol. 2020;4:34-40.

Jain N, Choudhury A, Sharma J, Kumar V, De Divyendu, Tiwar R. A Review of Novel Coronavirus Infection (Coronavirus Disease-19). Global J Trans Med. 2020(5):1.

Zhong J, Tang J, Ye C, Dong L. The immunology of COVID-19: is immune modulation an option for treatment? 2020;2.

Bauer SR, Kapoor A, Rath M, Thomas SA. What is role of supplementation with ascorbic acid, zinc, vitamin D, or N-acetylcysteine for prevention or treatment of COVID-19? Cleveland clinic j med. 2020.

National Center for Biotechnology Information (2020) PubChem Compound Summary for CID 54670067, Ascorbic acid. Available from: https://pubchem.ncbi.nlm.nin.gov/compound/Ascorbic-acid. Accessed on September 3, 2020.

Grosso G, Mistretta A, Bei R, Marventano S, Calabrese G, Masurlli L. Effects of vitamin C on health: A review Of Evidence. Frontiers biosci. 2013;18(3):1017-29.

Steven C. Rumsey and Mark Levine. Absorption, transport, and disposition of ascorbic acid in humans. J nutritional biochem. 1998;3(9):116-30.

Bauer SR, Kapoor A, Rath M, Thomas SA. What is role of supplementation with ascorbic acid, zinc, vitamin D, or N-acetylcysteine for prevention or treatment of COVID-19? Cleveland Clinic J Med. 2020.

Colunga Biancatelli RM, Berrill M, Catravas JD, Marik PE. Quercetin and Vitamin C: an experimental, synergistic therapy for the prevention and Treatment of SARS-CoV-2 Related Disease (COVID-19). Frontiers Immunol. 2020;(11):1451.

Vergin J. Vitamins are essential in the fight against COVID-19. Available at: https://www.msn.com/en-us/health/nutrition/vitamins-are-essential-in-the-fight-against-covid-19. Accessed on 8 August 2020.

National institute of health. 22. Vitamins, herbs, and dietary supplements. Available at: https://search.nih.gov/search?utf8=%E2%9C%93&affiliate=nih&query=vitamin+c&commit=Search. Accessed on 05th August 2020.

Bobroff LB, Valentín-Oquendo I. Facts about Vitamin C. IFAS University of Florida. 2017;1-2.

Vitamins, herbs, and dietary supplements, ascorbic acid. Available at: www.rxlist.com. Accessed on 05th August 2020.

Colunga Biancatelli RM, Berrill M, Catravas JD, Marik PE. Quercetin and Vitamin C: an experimental, synergistic therapy for the prevention and Treatment of SARS-CoV-2 Related Disease (COVID-19). frontiers immunol. 2020;(11):1451.

27 Health and Nutrition Tips That Are Actually Evidence-Based. Available from: https://www.healthline.com> nutrition. Accessed on 8/8/2020.