A study to evaluate the impact of patient counselling on the quality of life of female patients with recurrent urinary tract infection

Syama Gopinath; Anju P. C.; I. John Wesley; Prasobh G. R.

doi:10.18203/2319-2003.ijbcp20205125

Authors

Syama Gopinath Department of Pharmacy Practice, Sree Krishna College of Pharmacy and Research Centre, Trivandrum, Kerala, India
Anju P. C. Department of Pharmacy Practice, Sree Krishna College of Pharmacy and Research Centre, Trivandrum, Kerala, India
I. John Wesley Department of Pharmacy Practice, Sree Krishna College of Pharmacy and Research Centre, Trivandrum, Kerala, India
Prasobh G. R. Department of Pharmacy Practice, Sree Krishna College of Pharmacy and Research Centre, Trivandrum, Kerala, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20205125

Keywords:

Recurrence, KAP, EQ-5D-5L, UTI, Quality of life

Abstract

Background: Recurrence of urinary tract infections (UTI) are either due to re infection or relapse. Overall likelihood of developing UTI is approximately 30 times higher in women than men due to their anatomical peculiarities and are normally treated with antibiotics. To evaluate effectiveness of patient counselling in prevention of recurrent UTI in female patients to reduce the risk of developing Antibiotic resistance and assess the quality of life of patients.

Methods: A prospective observational study was carried out for a period of 6 months and samples were taken from the urology department of cosmopolitan hospital, Trivandrum, Kerala. Patient counseling was given regarding the disease, drugs and lifestyle modifications. A suitably validated KAP questionnaire was provided to each patient at their visits. By using an EQ-5D-5L questionnaire the quality of life of patients were assessed and analyzed.

Results: 84 patients were analyzed. After the counseling knowledge level significantly improved to good from 6.9% to 72.4%, the positive attitude level was improved from 35.6 to 57.5% and the practice level was improved to good from 25.3 to 43.7%. The QOL improved to best from 1.2 to 71.4%. After counseling incidence rate was decreased to zero. The mostly observed risk factor was decreased water intake (69%). The common age group observed was 31-50 (41.7%).

Conclusions: Patient counseling had an important impact on medication adherence and QOL of female patients with recurrent UTI. Effective patient counseling and better compliance decreased the incidence of recurrence and improved the quality of life of patients.

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References

Hudson JQ, Chaudhary K. Chronic Kidney Disease: Therapeutic approach for the management of complications. In, Joseph T Di Piro (ed). Pharmacotherapy: A Pathophysiologic Approach, 6th ed. New York, Medical Publishing Division. 2005;822-27.

Mason DL, Assimon MM. Chronic Kidney Disease. In, Brian K Alldredge (ed). Applied Therapeutics: The clinical use of drugs, 10th ed. USA, Williams and wilkins. 2013;764-67.

Marriott J, Cockwell P, Stringer S. Chronic kidney disease and end stage renal disease. In, Roger Walker(ed). Clinical Pharmacy and Therapeutics, 5th ed. London, Elsevier. 2012;272-6.

Tripathi KD. Antihypertensive drugs. In, Tripathi(ed). Essentials of Medical Pharmacology, 8th ed. New Delhi, Jaypee Brothers Medical Publishers. 2019;604-18.

Mohan H. The Kidney and Lower Urinary Tract. Text Book of Pathology, 7th ed. New Delhi, Jaypee brothers’ medical publishers. 2015;651-56.

Machin D, Day S, Green S. Text book of clinical trial, 2nd ed. 2010;593-94.

Ravishankar K, Kiran Mayi GVN. Clinical pharmacy and pharmacotherapeutics, 2nd ed. 2018;365.

Colledge NR, Walker BR, Ralston Sh. In, Davidson (ed). Principal and Practice of Medicine, 21st ed. 2010;459.

Greene RJ, Harris ND. Pathology and Therapeutics for Pharmacist: A basis for clinical pharmacy practice, 3rd ed. 2008;903.

British National Formulary, BHJ group. 2012;18.

Nseir W, Farah R, Mahamid M, Ahmad HS, Mograbi J, Taha M, Artul S. Obesity and recurrent urinary tract infections in premenopausal women: a retrospective study. Int J Infect Dis. 2015;41:32-5.

Polewski MA, Krueger CG, Reed JD, Leyer G. Ability of cranberry proanthocyanidins in combination with a probiotic formulation to inhibit in vitro invasion of gut epithelial cells by extra-intestinal pathogenic E. coli. J Functional Foods. 2016;25:123-34.

Dune T, Hilt E, Price T, Brincat C, Fitzgerald C, Brubaker L et al. Specific urinary tract infection symptoms in women relate to uropathogens while false negatives of standard urine cultures may delay patient treatment. Obstet Gynecol. 2017;130(4):718-25.

Raz R, Chazan B, Dan M. Cranberry Juice and Urinary Tract Infection Review article. Clin Infect Dis. 2004;38(10):1413-9.

Price TK, Dune T, Hilt EE. The Clinical Urine Culture: Enhanced Techniques Improve Detection of Clinically Relevant Microorganisms. J clinical microbiology. 2019;54(5):1216-22.

Chang SJ. Reliability and Validity of a Chinese Version of Urinary Tract Infection Symptom Assessment Questionnaire. 2015;41(4):729-38.

Makwana SP, Solanki MN. Comparative analysis of safety and efficacy of cefotaxime/sulbactam verses piperacillin/tazobactam combinations in the treatment of complicated urinary tract infections. Int J Basic Clin Pharmacol. 2019.

Howella A, Souzab D, Rollerc M, Fromentinb E. Comparison of the Anti-Adhesion Activity of Three Different Cranberry Extracts on Uropathogenic P-fimbriated Escherichia coli: A Randomized, Double-blind, Placebo Controlled, Ex Vivo Acute Study: Natural Product Communications. 2015;10(7):1215-8.

Wing DA, Rumney PJ, Preslicka C, Chung JH. Daily cranberry juice for the prevention of asymptomatic bacteriuria in pregnancy: A randomized controlled pilot study. J Urol. 2008;180(4):1367-72.

Liska DJ, Kern HJ, Maki KC. Cranberries and Urinary Tract Infections: How Can the Same Evidence Lead To Conflicting Advice? Am Society Nutri. 2016;7(3):498-506.

Remis RS, Gurwith M. Risk factors for urinary tract infection. Am J epidemiol. 1987;12(4):85-94.

Gupta K, Scholes D, Stamm WE. Increase in prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis. J Am Med Assoc. 199;2081:73-8.

Puvadae RC, Muthukumar VA. Impact of patient counselling on the knowledge, aptitude, practice and quality of life in patients with hypertension with diabetes mellitus. IJPER. 2018;52(2):305-10.

Clayson D, Wild D, Doll H, Keating K, Gondek K. Validation of A Patient-Administered Questionnaire to Measure The Severity And Bother sameness Of Lower Urinary Tract Symptoms In Uncomplicated Urinary Tract Infection (UTI): The UTI Symptom Assessment Questionnaire. 2005;96(3):350-9.

Schaeffer AJ, Stuppy BA. Efficacy and safety of self-start therapy in women with recurrent urinary tract infection. J Urol. 1999;161:207-11.