Dapsone induced hypersensitivity syndrome: a case report
DOI:
https://doi.org/10.18203/2319-2003.ijbcp20204106Keywords:
Dapsone, Hypersensitivity syndrome, HepatitisAbstract
Dapsone is an anti-leprotic drug. It may cause a severe adverse effect known as dapsone hypersensitivity syndrome which involves fever, chills, rash, and internal organ involvement. We report a case of a patient who is 30 years old male presented with fever, skin desquamation, and hepatitis. The case is being reported to emphasize the need to diagnose and manage dapsone hypersensitivity syndrome.
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References
Vinod KV, Arun K, Dutta TK. Dapsone hypersensitivity syndrome: A rare life
threatening complication of dapsone therapy. J Pharmacol Pharmacother. 2013;4(2):158-60.
Gavilanes MC, Palacio AL, Chellini PR, Nery JA, Rego JG. Dapsone hypersensitivity syndrome in a lepromatous leprosy patient- A case report. Lepr Rev. 2015;86:186-90.
Alungal J, Abdulla MC, Kunnummal NK, Sivadasan A. Dapsone- induced hypersensitivity syndrome, haemolytic anemia, and severe agranulocytosis. Int J Nutr Pharmacol Neurol Dis. 2015;5:113-6.
Grace M. An unusual case of dapsone syndrome. Indian Dermatol Online J. 2011;2:88-90.
Hamm RL. Drug-hypersensitivity syndrome: diagnosis and treatment. J Am Coll Clin Wound Spec. 2012;3(4):7781.
Watanabe H. Recent Advances in Drug-Induced Hypersensitivity Syndrome/DrugReaction with Eosinophilia and Systemic Symptoms. J Immunol Res. 2018;5163129.
Rademaker M, Maling T. Drug Hypersensivity syndrome. Medsafe. 2003;24(2):22-3.