Comparative study and assessment of the knowledge, attitude and practice of pharmacovigilance among first, second and third professional medical students of PMCH, Dhanbad
Keywords:ADR, Attitude, KAP, Knowledge, Medical students, Pharmacovigilance, Practices
Background: Pharmacovigilance awareness among medical students is very important for preventing ADR underreporting. Present study was conducted to know extent of Pharmacovigilance awareness among students and impact of Pharmacovigilance teaching.
Methods: Questionnaire based study about KAP towards ADR and Pharmacovigilance was carried out at Patliputra Medical College, Dhanbad. Of 150 questionnaires distributed to first, second and third professional students, 106 were returned.
Results: Pharmacovigilance Awareness was 20% in 1st, 91% in 2nd and 94% in 3rd Professional students. Only 10% of 1st, 82% of 2nd and 88% of 3rd Professional students knew about Pharmacovigilance and its purpose. Regarding International and National ADR monitoring body, only 7% of 1st, 50% of 2nd and 63% of 3rd professional students knew. Only 13% of 1st, 45% of 2nd and 56% of 3rd Professional students knew about local AMC. 40% of 1st, 86% of 2nd and 88% of 3rd professional students wanted detailed curricular teaching of Pharmacovigilance. 17% of 1st professional students had seen ADR, none (0%) had seen /reported ADR form. Of 2nd and 3rd professional students, 45% and 75% had seen ADR but only 34% and 56% had seen ADR form and 19% and 38% had reported ADR/seen ADR reporting.
Conclusions: 2nd and 3rd professional students had better knowledge and attitude towards pharmacovigilance. As 1st professional students underwent pharmacovigilance teaching, their KAP improved significantly. There existed huge gap between ADR experienced and ADR reporting by all medical students.
The safety of medicines in public health programmes: pharmacovigilance an essential tool- World Health Organization. 2006. Available at: https://www.who. int/medicines/areas/qualitysafety/safetyefficacy/Pharmacovigilance B.pdf. Accessed on 24 June 2020.
McBride WG. Thalidomide and congenital abnormalities. Lancet. 1961;2(1358):90927-8.
Making medicines safer- Published by Uppsala Monitoring Centre. Available at: https://view. publitas.com/uppsala-monitoring-centre/making-medicines-safer. Accessed on 24 June 2020.
Mahajan MM, Thatte UM, Gogtay NJ, Deshpande S. An analysis of completeness and quality of adverse drug reaction reports at an adverse drug reaction monitoring centre in Western India. Perspect Clin Res. 2018;9:123-6.
Gupta M, Kharb P, Kalaiselvan V, Shridhar M, Singh GN, Kshirsagar N, et al. World Health Organization. Safety of medicines: pharmacovigilance programme of India. WHO Drug Information. 2018;32(1):10-7.
Nimesh S, Chaudhary A, Sharma A, Negi KD. Pharmacovigilance Programme of India: A Review. Acta Scient Pharm Sci. 2019;3(9):12-7.
Pharmacovigilance Programme of India (PvPI). Performance Report 2015-16. Available at: http://www.ipc.gov.in/PvPI/pub/Pharmacovigilance%20Programme%20of%20India%20Annual%20performance%20Report%202015-2016.pdf. Accessed on 24 June 2020.
Meher BR, Joshua N, Asha B, Mukherji D. Awareness of pharmacovigilance among undergraduate medical students. Perspect Clin Res. 2015;6(4):217-21.
Inácio P, Cavaco A, Airaksinen M. The value of patient reporting to the pharmacovigilance system: a systematic Review: Br J Clin Pharmacol. 2017;83(2):227-46.
Parthiban G, Nileshraj G, Mangaiarkkarasi A, Ali MR. A survey on knowledge, attitude and awareness of pharmacovigilance among medical students in a teaching hospital, Puducherry. Indian J Basic Appl Med Res. 2015;5(1):198-203.
Gaude OS, Sa SD. Assessment of knowledge, attitude, and practices of pharmacovigilance and adverse drug reaction reporting among final year medical students- a questionnaire-based study in a tertiary care hospital in Goa. Nat J Physiol Pharm Pharmacol. 2018;8(12):1657-61.
Vakade KP, Sangisetti VM, Binayke MV, Abhavathi VN, Nayak BB. An evaluation of knowledge, attitude and practice of pharmacovigilance among interns in a tertiary care teaching hospital of North Maharashtra. Int J Basic Clin Pharmacol. 2016;5(6):2321-5.
Chhabra KG, Sharma A, Chhabra C, Reddy JJ, Deolia SG, Mittal Y. Knowledge, attitude, and practices regarding pharmacovigilance and adverse drug reaction reporting among dental students in a teaching hospital, Jodhpur, India: a cross-sectional study. J Contemp Dent Pract. 2017;18(10):964-9.
Ganesan S, Sandhiya S, Reddy KC, Subrahmanyam DK, Adithan C. The impact of the educational intervention on knowledge, attitude, and practice of pharmacovigilance toward adverse drug reactions reporting among health-care professionals in a Tertiary Care Hospital in South India. J Nat Sc Biol Med. 2017;8:203-9.
Upadhyaya HB, Vora MB, Nagar JG, Patel PB. Knowledge, attitude and practices toward pharmacovigilance and adverse drug reactions in postgraduate students of tertiary care hospital in Gujarat. J Adv Pharm Technol Res. 2015;6:29-34.
Reumerman M, Tichelaar J, Piersma B, Richir MC, van Agtmael MA. Urgent need to modernize pharmacovigilance education in healthcare curricula: review of the literature. Eur J Clin Pharmacol. 2018;74:1235-48.
Schutte T, Tichelaar J, Reumerman MO, van Puijenbroek EP, Richir MC, van Agtmael MA. Learning by doing in the student-run pharmacovigilance programme. Clin Therap. 2017;39(8):e2.