How effective is intra-cuff lignocaine in reducing post-operative sore throat and emergence cough: a comparative study


  • Jithin Mathew Abraham Department of Anaesthesiology, Believers Church Medical College, Thiruvalla, ‎Kerala, India
  • Saramma Abraham Department of Anaesthesiology, Pushpagiri Medical College, Thiruvalla, Kerala, India
  • Sangeetha Merrin Varghese Department of Community Medicine, Believers Church Medical College, Thiruvalla, Kerala, India



Intra-cuff, Lignocaine, Sore throat, Intubation, Emergence cough


Background: Sore throat and cough during emergence are common side effects of general anaesthesia and its incidence is reported by 30-70% of patients after tracheal intubation. Also, not to forget the hemodynamic fluctuations associated with it, adds on to the magnitude of the problem. Thinking of a simple and cost-effective way to tackle this problem, this study was undertaken to determine the benefits of using intra-cuff lignocaine to prevent post intubation sore throat and emergence cough. The objective of this study to assess the efficacy of intra-cuff 2% lignocaine solution, in reducing emergence cough and post-operative sore throat after extubation in general surgery patients intubated for 2-4 hours.

Methods: A prospective observational study where 100 ASA I and II status patients divided into 2 groups of 50 each was compared. In one group ETT cuff was filled with air, while in the other group, 2% plain lignocaine solution was used. Side effects like sore throat, coughing and blood pressure changes were assessed. Chi square and t-tests were used to compare the findings.

Results: Among those patients where intra-cuff lignocaine was used, only 27.5% complained of sore throat and 12.5% had emergence cough, whereas among those patients where intra-cuff air was used, 72.5% had post-operative sore throat and 87.5% of patients had cough on emergence.

Conclusions: This study proves that 2% intra-cuff lignocaine is an effective method in reducing post-operative sore throat and emergence cough and thereby beneficial in controlling the hemodynamic changes associated with emergence.


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How to Cite

Abraham, J. M., Abraham, S., & Varghese, S. M. (2020). How effective is intra-cuff lignocaine in reducing post-operative sore throat and emergence cough: a comparative study. International Journal of Basic & Clinical Pharmacology, 9(8), 1226–1231.



Original Research Articles