A prospective study on antibiotic prescribing pattern among in-patients of medicine department of a tertiary care hospital


  • Anulakshmi S. Department of Pharmacology, Government Medical College, Kozhikode, Kerala
  • Annapurna Yadavalli Department of Pharmacology, Government Medical College, Kozhikode, Kerala




Antimicrobial resistance, Hospital antibiotic policy, National list of essential medicines


Background: Irrational prescription is a major contributor to the antimicrobial resistance. Tertiary care centres in a state are the centres of excellence where policies are framed. So, they have an important role in promoting rational antibiotic prescription.

Methods: The study was conducted on in-patients of medicine ward in government medical college, Calicut, for a period of 2 months (January to February 2018), The data was collected from IP case records of patients. The parameters checked includes appropriateness of the antibiotic as, to whether it is according to our hospital antibiotic policy, whether de-escalation and change to oral drug was done, whether it is prescribed by generic name, is it given as fixed drug combination (FDC), is it from national list of essential medicine.

Results: Among the 135-prescription analyzed, total 225 antibiotics were used. Cephalosporins (32%) were the most commonly used. Of this only 40% was given by generic prescription. 27% was FDCs. 55% was from national list of essential medicines and 69% of them were ‘WATCH’ drug according to WHO Antibiotic Policy. Regarding appropriateness of prescriptions around 56% included right drug, 93% had right dose and frequency, and 70% had right duration and 100% were given through right route.

Conclusions: Strict adherence to hospital antibiotic policy and plan for effective teaching programs regarding antibiotic resistance and importance of rational prescription of antibiotics can improve the quality of antibiotic prescription and minimize antibiotic resistance.


Huttner A, Harbarth S, Carlet J. Antimicrobial resistance: a global view from the 2013 World Healthcare-Associated Infections Forum. Antimicrob Resist Infect Control. 2013;2(1):31.

Ghafur A. The Chennai declaration Recommendations of a road map - to tackle the challenge of antimicrobial resistance - a joint meeting of medical societies of India. Indian J Cancer. 2012;49(4):84-95.

Gerding DN. The search for good antimicrobial stewardship. Jt Comm J Qual Improv. 2001;27:403-4.

Baidya S, Hazra A. A study of antimicrobial use in children admitted to pediatric medicine ward of a tertiary care hospital. Indian J Pharma. 2017:26;1:9-14.

Sengupta S. Variations in antibiotic use across India: multi-centre study through Global Point Prevalence survey. J Hospital Infection. 2019;103(13):11-4.

Remesh A, Salim S. Antibiotics prescribing pattern in the in-patient departments of a tertiary care hospital. Arch Pharm Pract. 2013;4(2):71-6.

Ahmed A, Revankar M. Study the Prescription Pattern of Antibiotics in the Medicine Department in a Teaching Hospital: A Descriptive Study. Int J Toxicol Pharmacol Res. 2014;6;2:43-6.

Abhijit K, Jain P. A study monitoring prescription pattern of antibiotics in a tertiary care hospital in North India. Int J Basic Clin Pharmacol. 2014;3(6):1006-11.

Rajalingam B, Alex AS. Assessment of Rational Use of Antibiotics in a Private Tertiary Care Teaching Hospital. Indian J Pharm Pract. 2016;9(1):14-6.




How to Cite

S., A., & Yadavalli, A. (2020). A prospective study on antibiotic prescribing pattern among in-patients of medicine department of a tertiary care hospital. International Journal of Basic & Clinical Pharmacology, 9(6), 902–905. https://doi.org/10.18203/2319-2003.ijbcp20202179



Original Research Articles