DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20204087

Study of efficacy and adverse effect of fluticasone and formoterol combination in bronchial asthma

Sharad Chaddha, Tajinder Kaur

Abstract


Background: Bronchial asthma is a chronic inflammatory disorder of the airways associated with airway hyperresponsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing particularly at night or in the early morning.

Methods: This study has recruited 25 newly (male/female) cases of Bronchial Asthma diagnosed on the basis of spirometry in the Department of Pulmonary Medicine, Era’s Lucknow Medical College & Hospital (ELMC&H). Patients were received Fluticasone/Formoterol (200/10 μg OD). The drugs were administered through metered-dose inhaler (MDI).

Results: The mean forced expiratory volume recorded before treatment 54.92±4.47 in a group who were treated with formoterol/fluticasone combination changed to 75.48±5.03 after the treatment. No significant adverse effect of this regimens was observed.

Conclusions: The results of this study revealed this regimen showed a significant improvement in lung functions without any significant adverse event.


Keywords


Fluticasone/Formoterol, Forced expiratory volume in the first second, Bronchial asthma

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