Amoxicillin induced toxic epidermal necrolysis

Authors

  • Lakshmi Narasimha G. Department of Pharmacy Practice, Annamacharya College of Pharmacy, Rajampeta, Kadapa, Andhra Pradesh
  • Kalpana P. Department of Pharmacy Practice, Annamacharya College of Pharmacy, Rajampeta, Kadapa, Andhra Pradesh

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20200731

Keywords:

Amoxicillin, Adverse drug reactions, Life threatening, Mucocutaneous eruptions, Skin sloughing, Toxic epidermal necrolysis

Abstract

Toxic epidermal necrolysis (TEN) is a rare life-threatening adverse drug reaction associated with mucocutaneous eruptions and peeling of skin (sloughing) mostly caused by drugs like sulphonamides, beta lactams, carbamazepine and non-steroidal anti-inflammatory drugs (NSAIDs). Amoxicillin is a broad spectrum, bactericidal, Beta-lactam antibiotic used in treatment of various infections. Here by we have reported the case of amoxicillin induced severe toxic epidermal necrolysis. A Patient admitted in the hospital with the symptoms of epidermal sloughing that resulted in bare dermis as he received Amoxicillin drug for his diagnosis of fever. After clear examination TEN was confirmed and suspected with the cause due to Amoxicillin. The drug was stopped and patient was treated with other drugs for symptomatic cure. The patient was recovered from his condition and improved significantly.

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Author Biographies

Lakshmi Narasimha G., Department of Pharmacy Practice, Annamacharya College of Pharmacy, Rajampeta, Kadapa, Andhra Pradesh

Departement of Pharmacy Practice 

Student, Pharm.D

Kalpana P., Department of Pharmacy Practice, Annamacharya College of Pharmacy, Rajampeta, Kadapa, Andhra Pradesh

Departement of Pharmacy Practice 

Student, Pharm.D

References

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Published

2020-02-25

How to Cite

Narasimha G., L., & P., K. (2020). Amoxicillin induced toxic epidermal necrolysis. International Journal of Basic & Clinical Pharmacology, 9(3), 510–512. https://doi.org/10.18203/2319-2003.ijbcp20200731

Issue

Section

Case Reports