Antibiotic sensitivity pattern of bacterial isolates from sputum samples of admitted patients with acute lower respiratory tract infections in a tertiary care teaching hospital of Tripura: a hospital record-based study

Shubhaleena Debnath; Debasree Bhaumik; Maitrayee Chakraborty; Ranjib Ghosh; Lakshman Das; Prithul Bhattacharjee

doi:10.18203/2319-2003.ijbcp20200172

Authors

Shubhaleena Debnath Department of Pharmacology, Tripura Medical College and Dr. B. R. Ambedkar Memorial Teaching Hospital, Agartala, Tripura, India
Debasree Bhaumik Department of Pharmacology, Tripura Medical College and Dr. B. R. Ambedkar Memorial Teaching Hospital, Agartala, Tripura, India
Maitrayee Chakraborty Department of Pharmacology, Tripura Medical College and Dr. B. R. Ambedkar Memorial Teaching Hospital, Agartala, Tripura, India
Ranjib Ghosh Department of Pharmacology, Tripura Medical College and Dr. B. R. Ambedkar Memorial Teaching Hospital, Agartala, Tripura, India
Lakshman Das Department of Pharmacology, Tripura Medical College and Dr. B. R. Ambedkar Memorial Teaching Hospital, Agartala, Tripura, India
Prithul Bhattacharjee Department of Pharmacology, Tripura Medical College and Dr. B. R. Ambedkar Memorial Teaching Hospital, Agartala, Tripura, India

DOI:

https://doi.org/10.18203/2319-2003.ijbcp20200172

Keywords:

Antibiotic resistance, Klebsiella, Acinetobacter, Lower respiratory tract infection

Abstract

Background: Antibiotics are frequently used for various infectious diseases e.g., acute lower respiratory tract infection (ALRTI). But, injudicious use of antibiotics often leads to antibiotic resistance which is an emerging problem. The objective of this study was taken up to analyse the antimicrobial sensitivity pattern of pathogens isolated from the sputum samples of admitted patients suffering from ALRTI in a tertiary care teaching hospital.

Methods: It is a hospital record-based study with a sample size of 393.

Results: Klebsiella (52.16%) was the most common organism followed by Acinetobacter (13.49%) and Pseudomonas (13.23%) isolated from the sputum sample. Imipenem, piperacillin/tazobactam combination and gentamicin was sensitive against Klebsiella and Pseudomonas and the association were statistically significant. Acinetobacter was resistant to ceftriaxone.

Conclusions: The commonest pathogens isolated from the sputum samples were Klebsiella followed by Acinetobacter and Pseudomonas. Imipenem, piperacillin/tazobactam combination and gentamicin was sensitive against Klebsiella and Pseudomonas.

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