Awareness of over the counter antibiotics to combat antimicrobial resistance
DOI:
https://doi.org/10.18203/2319-2003.ijbcp20195281Keywords:
Awareness, OTC, Misuse, AMRAbstract
Background: In India there is wide use of over the counter (OTC) antibiotics and unawareness of its harmful effects. In India dispensing antibiotics without prescription is a major contribution factor in development of antimicrobial resistance (AMR). The objectives of the present study were to evaluate awareness and proper use of OTC antibiotics in the community.
Methods: Responses to a questionnaire covering various aspects on awareness and usage of OTC antibiotics were obtained from 100 families and 100 pharmacy shops in the community by second year MBBS students after permission from institutional ethical committee. The study period was from January 2019 to June 2019.
Results: Among 100 responders 78% used OTC antibiotics for frequently reported illness like common cold (58%), body- ache (19%), fever (13%) and cough (10%). Most common reason for using OTC antibiotic is to avoid high consultation fees (64%).76% pharmacy dispense antibiotics without prescription. 60% pharmacy unaware of increase chance of developing resistance due to OTC antibiotics. 80% pharmacy maintain register book and were aware of laws and regulations of OTC prescription but still 70% dispense drugs due to fear of losing sales and profit. 50% pharmacy said they encourage patients to consult the physician and get the prescription. Most common antibiotic sold without prescription is amoxicillin (51%) and azithromycin (38%).
Conclusions: We have identified unawareness among people about use and harmful effects of using OTC antibiotics. Also pharmacies are not following rules and regulations for OTC drugs. So our aim is to increase public knowledge of proper use and harmful effects of OTC antibiotics and help our global program to reduce AMR.
References
Antibiotic resistance-Fact sheet. World Health Organization, 2016. Available at: http://www.who. int/mediacentre/factsheets/antibiotic-resistance/en/. Accessed on 19 September 2019.
Rezal RS, Hassali MA, Alrasheedy AA, Saleem F, Yusof FA, Godman B. Physicians’ knowledge, perceptions and behaviour towards antibiotic prescribing: a systematic review of the literature. Expert Rev Anti Infect Ther. 2015;13:665–80.
Hawkey PM. Action against antibiotic resistance: no time to lose. Lancet. 1998;351:1298–9.
Goossens H, Ferech M, Stichele RV, Elseviers M. ESAC Project Group. Outpatient antibiotic use in Europe and association with resistance: a cross national database study. Lancet. 2005;365:579–87.
Barker A, Verhoeven K, Ahsan M, Alam S, Sharma P, Sengupta S, et al. Social determinants of patient antibiotic misuse in Haryana, India. J Invest Med. 2016;64(4):935.
Bennadi D. Self-medication: a current challenge. J Basic Clin Pharm. 2014;5:19.
National Strategy against Antibiotic Resistance, 2015-2020. Norwegian Ministry of Health and Care Services; 2015.
Antibiotic resistance. Fact sheet-2017. Accessed on 16 June 2019. Available at: http://www.who.int/ mediacentre/factsheets/antibiotic-resistance/en/. Accessed on 19 September 2019.
Shroti R, Nayak N, Singh RM. A study on over the counter drugs in retail pharmacies in Indore city. Der Pharmacies Lettre. 2011;3(3):133–8.
Chioro A, Coll-Seck AM, Høie B, Moeloek N, Motsoaledi A, Rajatanavin R, et al. Antimicrobial resistance: a priority for global health action. Bull World Health Organ. 2015;93:439.
Parikh D, Sattigeri BM, Kumar A, Brahmbhatt S. A survey study on use of over the counter (OTC) drugs among medical students, nursing and clerical staff of a tertiary care teaching rural hospital Int J Res Med Sci. 2013;1(2):83-86.
Bertoldi AD, Camargo AC, Silveira MP, Menezes MP, Asscencao MC, Goncalves H. Self-medication among adolescents aged 18 years: the 1993 pelotas (Brazil) Birth cohort study. J Adolesc Health. 2014;55(2):175–81.
Togoobaatar G, Ikeda N, Ali M, Sonomjamts M, Dashdemberel S, Mori R, et al. Survey of non-prescribed use of antibiotics for children in an urban community in Mongolia. Bull World Health Organ. 2010;88:930–6.
Abasaeed AE, Vlcek J, Abuelkhair MA, Andrajati R, Elnour AA. A comparative study between prescribed and over-the-counter antibiotics. Saudi Med J. 2013;34:1048–54.
Al-Mohamadi A, Badr A, Mahfouz LB, Samargandi D, Ahdal AA. Dispensing medications without prescription at Saudi community pharmacy: extent and perception. Saudi Pharm J. 2011;21:13–8.
