A study on the knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among post graduate residents in Gandhi Medical College, Bhopal


  • Mukesh Hindoliya Department of Pharmacology, Gandhi Medical College, Bhopal, Madhya Pradesh, India
  • Faizan Chitapure Department of Pharmacology, Gandhi Medical College, Bhopal, Madhya Pradesh, India




Pharmacovigilance, Adverse drug reaction reporting, Postgraduate students, KAP study


Background: Resident doctors should consider adverse drug reaction (ADR) reporting as their professional obligation and should be aware of the existing pharmacovigilance mechanisms in their countries. In India, pharmacovigilance implementation is essential due to the absence of a vibrant ADR monitoring system. The present study primary objective was to evaluate the knowledge, attitude and practices (KAP) of the postgraduate students towards pharmacovigilance and ADR reporting in GMC, Bhopal as they observe and attend to the patients round the clock while the patient is admitted in the hospital.

Methods: A cross-sectional-observational study was carried out using a pretested questionnaire having 17 questions in all. Data was compiled, entered in Microsoft Excel sheet and analysed by descriptive statistics.

Results: A total of 127 duly filled responses were analysed. Study shows ADR is necessary and Pharmacovigilance should be taught in detail to postgraduate students is an important finding from our study. In this study there was also a wide gap between the ADR experienced in professional practice (71%) and ADR reported (23%).

Conclusions: In our present study, the average knowledge score was 64% in contrast to 32% residents who didn’t answered correctly. Though majority (87%) of the residents had a positive attitude towards awareness about Pharmacovigilance and ADR reporting, however in clinical scenario even as ADR reporting was considered to be important by a large majority of the participants, the actual practices of ADR reporting was very low.


Adverse Drug Events, Adverse Drug Reactions and Medication Errors (FAQs); VA Center for Medication Safety And VHA Pharmacy Benefits Management Strategic Healthcare Group and the Medical Advisory Panel: 2006.

Brown SD Jr, Landry FJ. Recognizing, reporting, and reducing adverse drug reactions. South Med J. 2001;94:370-3.

Ramesh M, Pandit J, Parthasarathi G. Adverse drug reactions in a south Indian hospital – Their severity and cost involved. Pharmacoepidemiol Drug Saf. 2003;12:687–92.

Available at: https://www.who.int/medicines/areas/ quality_safety/safety_efficacy/pharmvigi/en/. Accessed on 3 June 2019.

Adithan C. National pharmacovigilance programme. Indian J Pharmacol. 2005;37:34.

Pharmacovigilance Programme in India (PvPI)-Indian scenario. Available at: http://www.ipc.gov.in/ PvPI/Pv_home.html. Accessed on 7 December 2017.

Feely J, Moriarty S, O'Connor P. Stimulating reporting of adverse drug reactions by using a fee. BMJ. 1990;300:22–3.

Ahmad SR. Adverse drug event monitoring at the Food and Drug Administration. J Gen Intern Med. 2003;18:57–60.

Wysowski DK, Swartz L. Adverse drug event surveillance and drug withdrawals in the United States, 1969-2002: The importance of reporting suspected reactions. Arch Intern Med. 2005;165:1363–9.

Shirodkar SN. India become seventh largest contributor to WHO-UMC's drug safety data base. Available at: http://www.pharmabiz.com. Accessed on 22 April 2019.

Upadhyaya P, Seth V, Moghe VV, Sharma M, Ahmed M. Knowledge of adverse drug reaction reporting in first year postgraduate doctors in a medical college. Ther Clin Risk Manage. 2012;8:307–12.

Remesh A. Identifying the reasons for under reporting of ADR: A cross sectional survey. Res J Pharm Biol Chem Sci. 2012;3:1379–86.

Khan SA, Goyal C, Chandel N, Rafi M. Knowledge, attitude and practice of doctors to adverse drug reaction reporting in a teaching hospital in India: An observational study. J Nat Sci Biol Med. 2013;4:191–6.

Muraraiah S, Rajarathna K, Sreedhar D, Basavalingu D, Jayanthi CR. A questionnaire study to assess the knowledge, attitude and practice of Pharmacovigilance in a paediatric tertiary care centre. J Chem Pharm Res. 2011;3:416–22.

Hardeep, Bajaj JK, Kumar R. A survey on the knowledge, attitude and the practice of pharmacovigilance among the health care professionals in a teaching hospital in northern India. J Clin Diagn Res. 2013;7:97–9.

Gupta P, Udupa A. Adverse drug reaction reporting and pharmacovigilance: Knowledge, attitudes and perceptions among resident doctors. J Pharm Sci Res. 2011;3:1064–9.

Ghosh S, Ali S, Chhabra L, Prasad C, Gupta A. Investigation of attitudes and perception of medical practitioners on adverse drug reaction reporting - A pilot study. Pharma Res. 2010;3:1–9.

Chatterjee S, Lyle N, Ghosh S. A survey of the knowledge, attitude and practice of adverse drug reaction reporting by clinicians in eastern India. Drug Saf. 2006;29:641–2.

Vallano A, Cereza G, Pedròs C, Agustí A, Danés I, Aguilera C, et al. Obstacles and solutions for spontaneous reporting of adverse drug reactions in the hospital. Br J Clin Pharmacol. 2005;60:653–8.




How to Cite

Hindoliya, M., & Chitapure, F. (2019). A study on the knowledge, attitude and practice on adverse drug reactions and pharmacovigilance among post graduate residents in Gandhi Medical College, Bhopal. International Journal of Basic & Clinical Pharmacology, 8(9), 2108–2112. https://doi.org/10.18203/2319-2003.ijbcp20194123



Original Research Articles