Antimicrobial prescribing patterns in surgical inpatient of tertiary care hospital in Eastern India


  • Sumit Kumar Gupta Department of Surgery, IQ City Medical College and hospital, Durgapur, West Bengal, India
  • Siddhartha Ghosh Department of Pharmacology, IQ City Medical College and hospital, Durgapur, West Bengal, India



Antimicrobial, Cholelithiasis, Piperacillin, Prescription, Polypharmacy, Standard treatment guideline


Background: Antimicrobials form the cornerstone of prescriptions for treating infection. Surgical management cannot be possible without the use of antibiotics. Severity of infection, suspected spectrum of organisms and their sensitivity, co-morbidities of the patient, route of antibiotic administration are the important parameter to consider before selecting antibiotic.

Methods: Cross-sectional, hospital based, descriptive study was conducted in the ward of Surgery Department of IQ City Medical college, Durgapur over a period of 1 year. The relevant information was entered into the pretested preformats (containing name, age, sex, diagnosis, ongoing treatment as recorded from patients’ prescription slips or CRFs) and analyzed. Necessary permission was granted by the Institutional Ethical Committee and written informed consent was obtained from the patients prior to collecting their prescription slips/CRF.

Results: Commonest cause of hospitalization was cholelithiasis (318 (32.7%)). Antimicrobials were the most commonly prescribed drugs (1626 (31.6%)). Single antibiotic prescribing frequency are similar to two antibiotic prescribing (both 44%). Piperacillin+Tazobactum combination most commonly prescribe antibiotic.

Conclusions: Beta lactam antibiotic specifically Piperacillin (ATC class: J01D) were the most commonly prescribed antibiotic agents both before and after surgical procedures.


Tünger O, Dinç G, Ozbakkaloglu B, Atman UC, Algün U. Evaluation of rational antibiotic use. Int J Antimicrob Agents. 2000;15(2):131‑5.

Kanakambal S, Murugesh N, Shanthi M. Drug prescribing pattern in a tertiary care teaching hospital in Madurai (Tamilnadu). Ind J Pharmacol. 2001 May 1;33(3):223.

Awad AI, Himad HA. Drug-use practices in teaching hospitals of Khartoum State, Sudan. Eur J Clin Pharmacol. 2006 Dec 1;62(12):1087-93.

Patel V, Vaidya R, Naik D, Borker P. Irrational drug use in India: a prescription survey from Goa. J Postgrad Med. 2005 Jan 1;51(1):9-12.

Mohanty BK, Aswini M, Hasamnis AA, Patil SS, Murty KS, Jena SK. Prescription pattern in the department of medicine in a tertiary care hospital in south India. J clin diagn res. 2010 Feb;3:2047-51.

Tripathi KD. Essentials of medical pharmacology. 7th ed. Jaypee Brothers Publishers; 2013:71.

Laporte JR, Porta M, Capella DO. Drug utilization studies: a tool for determining the effectiveness of drug use. Br J Clin Pharmacol. 1983 Sep;16(3):301-4.

Umadevi S, Kumar S, Joseph NM, Easow JM, Kandhakumari G, Srirangaraj S, Raj S, Stephen S. Microbiological study of diabetic foot infections. Ind J Med Specialit. 2011 Jan 1;2(1):12-7.

Leekha S, Terrell CL, Edson RS. General principles of antimicrobial therapy. Mayo Clin Proceedings. 2011 Feb 1;86(2):156-67.

Laporte JR. Towards a healthy use of pharmaceuticals. Dev Dialogue. 1985;2:48-55.

Alanis AJ. Resistance to antibiotics: are we in the post-antibiotic era?. Arch Med Res. 2005 Nov 1;36(6):697-705.

Khade A, Bashir MS, Sheethal A. Prescription pattern in the department of surgery in a tribal district hospital of Andhra Pradesh, India. Ann Med Health Sci Res. 2013;3(3):438-41.

Harmeet SR, Nagarani MA, Moushumi R. A study on the drug prescribing pattern and use of antimicrobial agents at a tertiary care teaching hospital in eastern Nepal. Ind J pharmacol. 1998 May 1;30(3):175-78.

Tomson G. Drug utilization studies in Sri Lanka-Towards an understanding of medicine in society. Kongl Carolinska Medico Chirurgiska Institutet. 1990; I:1-5.

Tabish A, Jha RK, Rathod AM, Rathod RM, Gupta KK. Prescribing trend of analgesics in a tertiary health care setup of rural Vidarbha. Res J Pharm Biol Chem Sci. 2012;3(3):566-71.

Rahman MS, Begum ZA, Samad MK. Prescribing pattern of non-steroidal anti-inflammatory drugs at outpatient departments of teaching hospitals. Bangl J Pharmacol. 2007;2(1):1-6.

Desalegn AA. Assessment of drug use pattern using WHO prescribing indicators at Hawassa University teaching and referral hospital, south Ethiopia: a cross-sectional study. BMC Health Services Res. 2013 Dec;13(1):170.




How to Cite

Gupta, S. K., & Ghosh, S. (2019). Antimicrobial prescribing patterns in surgical inpatient of tertiary care hospital in Eastern India. International Journal of Basic & Clinical Pharmacology, 8(8), 1902–1905.



Original Research Articles