Published: 2019-04-23

Drug utilization patterns of antibiotics in outpatient department of educare dental hospital at Malappuram, Kerala, India

Fayisa K., Anas P. P., Sudhakar A.


Background: Drug utilization studies aims to evaluate factors related to the prescribing, dispensing, administering and taking of medication, and its associated events. Antibiotic prescription by dental practitioners has an important impact on the rate of general antibiotic prescription use, and an attempt has been made to establish a surveillance system for the monitoring and control of the use of these drugs.

Methods: Retrospective record-based study was conducted at outpatient department at Educare Dental College and Hospital, Chattipparamba, Malappuram, Kerala. About 2802 prescriptions were screened, drugs prescribed were noted, tabulated and analysed.

Results: Total no. of prescriptions 2802, total no. of antibiotics prescribed 2916, average no of antibiotics per prescription 1.04. Out of antibiotics prescribed 72% were monotherapy and 28% were fixed dose combination. Among antibiotics beta lactam antibiotics were commonly prescribed followed by nitroimidazoles and macrolides.

Conclusions: The study was conducted to analyze the drug utilization pattern in outpatient department at dental hospital. Most of prescription were rational, both monotherapy and polypharmacy were practiced. Safer drug with less adverse effect profile were considered. Among the antibiotic amoxicillin was the commonest.


Antibiotics, Drug utilization, Dentistry, Outpatient department, Penicillins, Prescription

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Shalini S, Ravichandran V, Mohanty BK, Dhanaraj SK, Saraswathi K. Drug Utelization Studies-An Overview. Int J Pharmaceut Sci Nanotechnol. 2010;3(1):803-10.

Wettermark B, Elseviers M, Almarsdottir AB. Drug Utilization Research: Methods and Applications, John Wiley & Sons, Ltd.2016;1:3-12.

Pratiti, Pratyay PD. Drug utilization Pattern in oral medicine Department of Saveetha Dental college, Tamilnadu, India. National J Med Res. 2015;5(1):271-4.

Jayanthi MK, Naidu SV. Drug utilization Pattern and pharmacoeconomic study in paediatric Dentistry at a tertiary hospital. Int J Pharma Pharmaceut Sci. 2013;6(2):70-2.

Shrikala B, Kranthi K. A prospective study on evaluation of antibiotic prescription practices in an intensive care unit of a tertiary care hospital. J Clin Diagn Res. 2010;4(6):3387-91.

van Houten MA, Luinge K, Laseur M, Kimpen JL. Antibiotic utilisation for hospitalised paediatric patients. Int J Antimicrob Agents. 1998;10(2):161-4.

Stallworth LE, Fick DM, Ownby DR, Waller JL. Antibiotic use in children who have asthma: results of retrospective database analysis. J Managed Care Pharma. 2005;11(8):657-62.

Bithi SS, Khan MM, Khan AU. Drug utilization study in orthopaedic units: Antibiotics prescribed in hospital out-patients in Dhaka, Bangladesh. Int Curr Pharmaceut J. 2014;3(9):318-21.

Takhar P, Yadav S, Dua S, Mahant S. Investigation of antibiotic usage pattern: A prospective drug utilization review. Der. Pharmacia. Lettre. 2011;3:301-6.

Ahmed MM, Harsoor A, Nizami S. A prospective study of drug utilization in patients attending ophthalmology outpatient department at KBN teaching and general hospital of Gulbarga, India. Int J Basic Clin Pharmacol. 2018;7(8):1-5.

Paudel KR, Sah NK, Jaiswal AK. Prevalence of pharmacotherapy in department of paediatric dentistry. Kathmandu Uni Med J. 2009;8(30):190-4.

Kaul R, Angrish P, Jain P, Saha S, Sengupta AV, Mukherjee S. A Survey on the Use of Antibiotics among the Dentists of Kolkata, West Bengal, India. Int J Clin Pediatr Dentistr. 2018 Mar;11(2):122-7.

Sharma D, Reeta KH, Badyal DK, Garg SK, Bhargava VK. Antimicrobial prescribing pattern in an Indian tertiary hospital. Indian J Physiol Pharmacol. 1998;42 (4):533-7.

Roda RP, Bagan JV, Bielsa JS, Pastor EC. Antibiotic use in dental practice. A review. Med Oral Patol Oral Cir Bucal. 2007;12(3):186-92.

Stanulović M, Jakovljević V, Rončević N. Drug utilization in paediatrics: non-medical factors affecting decision making by prescribers. Eur J Clin Pharmacol. 1984;27(2):237-41.