DOI: http://dx.doi.org/10.18203/2319-2003.ijbcp20191100

An evaluation of pattern of adverse drug reactions reporting by undergraduate medical students in a tertiary care hospital

Zorawar Singh Bali, Mohammad Younis Bhat, Samina Farhat, Urfan Nabi

Abstract


Background: Adverse drug reactions (ADRs) are an important cause of mortality and morbidity worldwide and reporting ADRs voluntarily is fundamental to medical drug safety surveillance but gross underreporting of ADRs is a cause for a concern. Being key health care professional, physicians, pharmacists and nurses have immense responsibility in reporting of ADRs. Therefore, the sensitization and involvement of undergraduate medical students can reduce underreporting. This study is aimed at evaluating knowledge, attitude and reporting of quality of ADRs by undergraduate medical students.

Methods: The study was conducted after sensitizing the second professional year undergraduate students about Pharmacovigilance as part of their internal assessment and asked them to submit reports of ADR observed during their clinical posting.

Results: A total of 82 ADR’s were reported after sensitization with majority of them i.e. 30 related to skin and appendages disorder followed by gastrointestinal tract with antibiotics i.e. 28 and analgesics being most common probable/possible culprits.

Conclusions: The response percentage of reporting ADRs was 54.66%. Medical students being future healthcare professionals should be exposed to ADR reporting during their clinical teaching posting as a part of sensitization and make them actively involved in reporting to improve detection rate and make Pharmacovigilance a success.


Keywords


Adverse drug reaction, Pharmacovigilance, Sensitization, Undergraduate medical student

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References


A report of WHO meeting, WHO technical report, International Drug Monotoring; The role of National centres, Ser. 1972;498;1-25.

Desai C, Iyer G, Panchal J, Shah S, Dikshit R. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspectives Clin Res. 2011;2(4):129-36.

Medicine Io. To Err Is Human: Building a Safer Health System. Washington, DC: The National Academies Press; 2000.

Carrasco-Garrido P, de Andrés LA, Barrera VH, de Miguel GÁ, Jiménez-García R. Trends of adverse drug reactions related-hospitalizations in Spain (2001-2006). BMC Health Services Res. 2010;10(1):287.

Herdeiro MT, Figueiras A, Polónia J, Gestal-Otero JJ. Physicians’ Attitudes and Adverse Drug Reaction Reporting. Drug Saf. 2005;28(9):825-33.

Eland, Belton, Grootheest V, et al. Attitudinal survey of voluntary reporting of adverse drug reactions. Br J Clin Pharmacol. 1999;48(4):623-7.

Gupta SK, Nayak RP, Shivaranjani R, Vidyarthi SK. A questionnaire study on the knowledge, attitude, and the practice of pharmacovigilance among the healthcare professionals in a teaching hospital in South India. Perspectives Clin Res. 2015; 6(1):45-52.

Rehan HS, Vasudev K, Tripathi CD. Adverse drug reaction monitoring: knowledge, attitude and practices of medical students and prescribers. Natl Med J India. 2002;15(1): 24-6.

Gaikwad NR, Yadav SS, Patil AB, Manjrekar PV, Jha RK. Awareness about adverse drug reactions monitoring among prescribers of rural teaching hospital of central India. JDMIMSU. 2009;4(3):173-6.

Muraraiah S, Rajarathna K, Sreedhar D, Basavalingu D, Jayanthi CR. A questionnaire study to assess the knowledge, attitude and practice of Pharmacovigilance in a paediatric tertiary care centre. J Chem Pharm Res. 2011;3(6):416-22.

Ramesh M, Pandit J, Parthasarathi G. Adverse drug reactions in a south Indian hospital-their severity and cost involved. Pharmacoepidemiol Drug Saf. 2003 Dec;12(8):687-92.

Rao PG, Archana B, Jose J. Implementation and results of an adverse drug reaction reporting programme at an Indian teaching hospital. Indian J Pharmacol. 2006 Jul 1;38(4):293-4.

Arulmani R, Rajendran SD, Suresh B. Adverse drug reaction monitoring in a secondary care hospital in South India. Br J Clin Pharmacol. 2008 Feb 1;65(2):210-6.

Jose J, Rao PGM. Pattern of adverse drug reactions notified by spontaneous reporting in an Indian tertiary care teaching hospital. Pharmacol Res. 2006;54(3):226-33.

Uppal R, Jhaj R, Malhotra S, India NM. Adverse drug reactions among inpatients in a north Indian referral hospital. Nat Med J f India. 2000 Jan 1;13(1):16-8.

Murphy BM, Frigo LC. Development, implementation, and results of a successful multidisciplinary adverse drug reaction reporting program in a university teaching hospital. Hospital Pharmacy. 1993 Dec; 28(12):1199-204.