Pharmacological role of atorvastatin in myocardium and smooth muscle progenitor cells


  • Suresh Kanna Department of Chemistry, Bharathiyar College of Engineering and Technology, Karaikal, Puducherry, Tamil Nadu, India
  • Jai Prabu Department of Biochemistry, Vinayaka Mission’s Medical College and Hospital, Karikal, Tamil Nadu, India
  • Vignesh Marimuthu Department of Human Genetics and Molecular Biology, Bharatiar University, Coimbatore, Tamil Nadu, India
  • Vijaya Anand Department of Human Genetics and Molecular Biology, Bharatiar University, Coimbatore, Tamil Nadu, India



Atorvastatin, Smooth muscle cells, Angiotensin, Myocardium


Atorvastatin is a synthetic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor with a great potency in the reduction of lipids and it has been well documented in both primary and secondary prevention studies. It exhibits pleiotropic properties in both in-vitro and in vivo conditions. Conversely, atorvastatin remain under-utilized in several situations. The main objective of this review is to focuses the pharmacological benefits, pleiotropic properties of the atorvastatin related to smooth muscle proliferation and myocardium.


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How to Cite

Kanna, S., Prabu, J., Marimuthu, V., & Anand, V. (2016). Pharmacological role of atorvastatin in myocardium and smooth muscle progenitor cells. International Journal of Basic & Clinical Pharmacology, 5(3), 605–608.



Review Articles