Pharmacological role of atorvastatin in myocardium and smooth muscle progenitor cells
DOI:
https://doi.org/10.18203/2319-2003.ijbcp20161498Keywords:
Atorvastatin, Smooth muscle cells, Angiotensin, MyocardiumAbstract
Atorvastatin is a synthetic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor with a great potency in the reduction of lipids and it has been well documented in both primary and secondary prevention studies. It exhibits pleiotropic properties in both in-vitro and in vivo conditions. Conversely, atorvastatin remain under-utilized in several situations. The main objective of this review is to focuses the pharmacological benefits, pleiotropic properties of the atorvastatin related to smooth muscle proliferation and myocardium.
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