Drug utilization study of bronchial asthma in adults at rural hospital


  • Ameya Puranik Department of Pharmacology, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India
  • Sangita Totade Department of Pharmacology, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India




Brochial asthma, Drug utilization, Prescription pattern, Rural hospital


Background: Asthma is rather a clinical syndrome than a disease with availability wide range of medications. Drug utilization studies are necessary to improve prescribing pattern among physicians.

Methods: The 250 study subjects were interviewed, and prescription data was recorded in a pre-designed case record form. The data was compiled using Microsoft excel and presented in a tabulated and graphical presentation.

Results: Out of 250 study subjects most of the study subjects are between 61-70 years of age. Majority of subjects are males (58%). Out of 250, (49%) are found out to be smokers. Dust, smoke and pollen are found out to be most common allergen. Most common type of asthma was mild intermittent (134) study subjects. Socio-economic status of was found out to be lower middle class in majority (158 out of 250). Large number of study population is suffering from co-morbid conditions such as URTI and COPD. Salbutamol was most common single drug used for nebulization therapy and most common combination is salbutamol + ipatropium bromide + budesonide. Most common oral drug used are methylxanthines and most frequently used intravenous drugs are deriphylline and hydrocortisone. Various antibiotics are prescribed to majority of subjects, most common was amoxicillin + clavulanic acid combination. Most commonly suffered adverse drug reaction between study subjects were gastrointestinal disturbances.

Conclusions: It is concluded that prescribing pattern for asthma at A.V.B.R.H. is not according to standard guidelines, hence it is need of the hour to encourage physicians to follow guidelines.


Global Initiative for Asthma. Global strategy for the diagnosis and prevention. Global Initiative for Asthma. 2017. Available at: https://ginasthma.org/wp-content/uploads/2017/02/wmsGINA-2017-main-report-final_V2.pdfAccessed October 2018.

Kay AB. Pathology of mild, severe, and fatal asthma. Am J Respiratory Critical Care Med. 1996 Aug 1;154(2):S66.

Bethesda (MD). Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. National Heart, Lung, and Blood Institute (US); 2007. Available at: https://www.ncbi.nlm.nih.gov/books/NBK7232/.

Horwitz RJ, Busse WW. Inflammation and asthma. Clin Chest Med. 1995 Dec;16(4):583-602.

Djukanović R, Wilson JW, Britten KM, Wilson SJ, Walls AF, Roche WR, et al. Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. Am Rev Respir Dis. 1992 Mar;145(3):669-74.

Lai CKW, Beasley R, Crane J, Foliaki S, Shah J, Weiland S, et al. Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2009 Jun;64(6):476-83.

To T, Stanojevic S, Moores G, Gershon AS, Bateman ED, Cruz AA, et al. Global asthma prevalence in adults: findings from the cross-sectional world health survey. BMC Public Health. 2012 Dec;12(1):204.

Cavkaytar O, Sekerel BE. Baseline management of asthma control. Allergol Immunopathol (Madr). 2014 Apr;42(2):162-8.

Jindal SK, Aggarwal AN, Gupta D, Agarwal R, Kumar R, Kaur T, et al. Indian study on epidemiology of asthma, respiratory symptoms and chronic bronchitis in adults (INSEARCH). Int J Tuberc Lung Dis Off J Int Union Tuberc Lung Dis. 2012 Sep;16(9):1270-7.

A view from the drug utilization review management organization sector - Jones - 1991 - Clinical Pharmacology & Therapeutics - Wiley Online Library. Available at: https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1038/clpt.1991.195. Accesses 31 July 2018.

Jagadeesan M. A study on concurrent drug utilization evaluation of antiasthmatic drugs in the tertiary care hospital. Int J Nov Trends Pharm Sci. 2016 Feb;6(1):14-9.

Arumugam V, Kothiyal P, Juyal V, Pandey A, Tripathi P. Drug utilization assessment in asthma therapy through prescription monitoring at Dehradun hospitals. Indian J Allergy Asthma Immunol. 2008;22(1):15-8.

Zahran HS, Bailey CM, Qin X, Moorman JE. Assessing asthma severity among children and adults with current asthma. J Asthma Off J Assoc Care Asthma. 2014 Aug;51(6):610-7.

B JD, Kulkarni GP. A retrospective study on drug utilization in patients with acute exacerbation of bronchial asthma in adults at tertiary teaching hospital in Bidar. Int J Basic Clin Pharmacol. 2017 Jan 28;6(2):389-92.

Pandey A, Tripathi P, Pandey RD. Prescription pattern in asthma therapy at Gorakhpur hospitals. Lung India. 2010 Jan 1;27(1):8.

Mahemuti G, Zhang H, Li J, Tieliwaerdi N, Ren L. Efficacy and side effects of intravenous theophylline in acute asthma: a systematic review and meta-analysis. Drug Design Develop Therapy. 2018;12:99-120.

Nair P, Milan SJ, Rowe BH. Addition of intravenous aminophylline to inhaled beta (2)-agonists in adults with acute asthma. Cochrane Database Syst Rev. 2012 Dec 12;12:CD002742.

Atmar RL, Guy E, Guntupalli KK, Zimmerman JL, Bandi VD, Baxter BD, et al. Respiratory Tract Viral Infections in Inner-City Asthmatic Adults. Arch Intern Med. 1998 Dec 7;158(22):2453-9.

Barrecheguren M, Esquinas C, Miravitlles M. The asthma-COPD overlap syndrome: a new entity? COPD Res Pract. 2015 Oct 22;1(1):8.

Jie Y, Isa ZM, Jie X, Ju ZL, Ismail NH. Urban vs. rural factors that affect adult asthma. Rev Environ Contam Toxicol. 2013;226:33-63.

Agarwal R, Dhooria S, Aggarwal AN, Maturu VN, Sehgal IS, Muthu V, et al. Guidelines for diagnosis and management of bronchial asthma: Joint ICS/NCCP (I) recommendations. Lung India. 2015 Apr 1;32(7):3.

Piipari R, Jaakkola JJK, Jaakkola N, Jaakkola MS. Smoking and asthma in adults. Eur Respir J. 2004 Nov 1;24(5):734-9.

Maiti S, Samajdar SS, Panda P, Prasad A, Pattanayak C, Das KL. Pharmacovigilance study in cases of bronchial asthma in tertiary care hospitals of eastern India. Indian J Pharm Pharmacol. 2016 Jul 28;2(2):85-9.




How to Cite

Puranik, A., & Totade, S. (2018). Drug utilization study of bronchial asthma in adults at rural hospital. International Journal of Basic & Clinical Pharmacology, 8(1), 120–127. https://doi.org/10.18203/2319-2003.ijbcp20185169



Original Research Articles